Related references
Note: Only part of the references are listed.Cancer-associated fibroblast (CAF)-derived IL32 promotes breast cancer cell invasion and metastasis via integrin β3-p38 MAPK signalling
Siyang Wen et al.
CANCER LETTERS (2019)
Cancer-associated fibroblasts: how do they contribute to metastasis?
Mei Qi Kwa et al.
CLINICAL & EXPERIMENTAL METASTASIS (2019)
Integrin 11 in pancreatic stellate cells regulates tumor stroma interaction in pancreatic cancer
Jonas Schnittert et al.
FASEB JOURNAL (2019)
Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration
Brunella Costanza et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Integrin α-3 ß-1's central role in breast cancer, melanoma and glioblastoma cell aggregation revealed by antibodies with blocking activity
Daniel F. Lusche et al.
MABS (2019)
Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function
Asma Begum et al.
PANCREAS (2019)
Blockade of integrin α3 attenuates human pancreatic cancer via inhibition of EGFR signalling
Jungwhoi Lee et al.
SCIENTIFIC REPORTS (2019)
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Eva A. Ebbing et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix
Kaoru Miyazaki et al.
SCIENTIFIC REPORTS (2019)
The Interaction between Laminin-332 and alpha 3 beta 1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells
Ana C. Martins Cavaco et al.
CANCERS (2019)
The two faces of enhanced stroma: Stroma acts as a tumor promoter and a steric obstacle
Claudia Tanja Mierke et al.
NMR IN BIOMEDICINE (2018)
Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration
Maria Kalli et al.
ANNALS OF BIOMEDICAL ENGINEERING (2018)
Integrin diversity brings specificity in mechanotransduction
Shailaja Seetharaman et al.
BIOLOGY OF THE CELL (2018)
Fibroblasts in the Tumor Microenvironment: Shield or Spear?
Twana Alkasalias et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Single-molecule measurements of the effect of force on Thy-1/αvβ3-integrin interaction using nonpurified proteins
Francesca Burgos-Bravo et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
What about αvβ3 integrins in molecular imaging in oncology?
Frederic Debordeaux et al.
NUCLEAR MEDICINE AND BIOLOGY (2018)
Integrin Activation: Implications for Axon Regeneration
Menghon Cheah et al.
CELLS (2018)
Integrin αvβ6 plays a bi-directional regulation role between colon cancer cells and cancer-associated fibroblasts
Cheng Peng et al.
BIOSCIENCE REPORTS (2018)
Desmoplastic Tumor Microenvironment and Immunotherapy in Cholangiocarcinoma
Dan Hogdall et al.
TRENDS IN CANCER (2018)
Cancer-associated fibroblast-derived Lumican promotes gastric cancer progression via the integrin β1-FAK signaling pathway
Xiaofeng Wang et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin
Begum Erdogan et al.
JOURNAL OF CELL BIOLOGY (2017)
Cancer-associated fibroblasts lead tumor invasion through integrin-β3-dependent fibronectin assembly
Youmna Attieh et al.
JOURNAL OF CELL BIOLOGY (2017)
Transient mechanical strain promotes the maturation of invadopodia and enhances cancer cell invasion in vitro
Alexander N. Gasparski et al.
JOURNAL OF CELL SCIENCE (2017)
Force regulated conformational change of integrin αvβ3
Yunfeng Chen et al.
MATRIX BIOLOGY (2017)
The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma
Asma Begum et al.
PLOS ONE (2017)
Fibronectin-guided migration of carcinoma collectives
Sandeep Gopal et al.
NATURE COMMUNICATIONS (2017)
Tissue Force Programs Cell Fate and Tumor Aggression
Jason J. Northey et al.
CANCER DISCOVERY (2017)
Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma
Baoqing Tian et al.
ONCOTARGET (2017)
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Xiongyan Wu et al.
ONCOTARGET (2017)
Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence
Janusz Franco-Barraza et al.
ELIFE (2017)
Fibronectin: How Its Aberrant Expression in Tumors May Improve Therapeutic Targeting
Jennifer Peyling Wang et al.
JOURNAL OF CANCER (2017)
u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression
S. Ciavarella et al.
BMC CANCER (2017)
Podoplanin Expression in Cancer-associated Fibroblasts Predicts Poor Prognosis in Patients with Squamous Cell Carcinoma of the Lung
Yohei Yurugi et al.
ANTICANCER RESEARCH (2017)
Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer
R. Navab et al.
ONCOGENE (2016)
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Philippe Gascard et al.
GENES & DEVELOPMENT (2016)
Front-Rear Polarization by Mechanical Cues: From Sincle Cells to Tissues
Benoit Ladoux et al.
TRENDS IN CELL BIOLOGY (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Mechanoreception at the cell membrane: More than the integrins
Alexander N. Gasparski et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)
How actin/myosin crosstalks guide the adhesion, locomotion and polarization of cells
Erich Sackmann
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
Tumor mechanics and metabolic dysfunction
Jason C. Tung et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma
Timothy J. Underwood et al.
JOURNAL OF PATHOLOGY (2015)
Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer
Ruchi Malik et al.
TRENDS IN BIOTECHNOLOGY (2015)
Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance
Laetitia Seguin et al.
TRENDS IN CELL BIOLOGY (2015)
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
Jean Albrengues et al.
NATURE COMMUNICATIONS (2015)
Compressive Stress Inhibits Proliferation in Tumor Spheroids through a Volume Limitation
Morgan Delarue et al.
BIOPHYSICAL JOURNAL (2014)
Rigidity sensing and adaptation through regulation of integrin types
Alberto Elosegui-Artola et al.
NATURE MATERIALS (2014)
Extracellular matrix assembly: a multiscale deconstruction
Janna K. Mouw et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer
X Sun et al.
ONCOGENE (2014)
Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis
Young I. Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
TGF-beta in CAF-mediated tumor growth and metastasis
A. Calon et al.
SEMINARS IN CANCER BIOLOGY (2014)
Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials
Hua Fang et al.
CANCER RESEARCH (2013)
Mechanical cues in cellular signalling and communication
Nickolay V. Bukoreshtliev et al.
CELL AND TISSUE RESEARCH (2013)
Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus
Sebastian F. Schoppmann et al.
CLINICAL & EXPERIMENTAL METASTASIS (2013)
Significance of podoplanin expression in cancer-associated fibroblasts: A comprehensive review
Bartosz Pula et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells
Wei Chen et al.
JOURNAL OF CELL BIOLOGY (2012)
Inhibition of Integrin α2β1 Ameliorates Glomerular Injury
Corina M. Borza et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
Mechanical compression drives cancer cells toward invasive phenotype
Janet M. Tse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
RGD-Binding Integrins in Prostate Cancer: Expression Patterns and Therapeutic Prospects against Bone Metastasis
Mark Sutherland et al.
Cancers (2012)
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
Hyung-Ok Lee et al.
BMC CANCER (2011)
Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
Jacky G. Goetz et al.
CELL (2011)
Podoplanin expression by cancer-associated fibroblasts predicts poor outcome in invasive ductal breast carcinoma
Bartosz Pula et al.
HISTOPATHOLOGY (2011)
Cancer Cell Invasion Is Enhanced by Applied Mechanical Stimulation
Shalini Menon et al.
PLOS ONE (2011)
Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer
Roya Navab et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Integrin Structure, Activation, and Interactions
Iain D. Campbell et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
An in vitro correlation of mechanical forces and metastatic capacity
Indrajyoti Indra et al.
PHYSICAL BIOLOGY (2011)
Activation of fibroblasts in cancer stroma
Kati Rasanen et al.
EXPERIMENTAL CELL RESEARCH (2010)
Incorporation of Tenascin-C into the Extracellular Matrix by Periostin Underlies an Extracellular Meshwork Architecture
Isao Kii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Methylation determines fibroblast activation and fibrogenesis in the kidney
Wibke Bechtel et al.
NATURE MEDICINE (2010)
Identification of Vitronectin as an Extrinsic Inducer of Cancer Stem Cell Differentiation and Tumor Formation
Elaine M. Hurt et al.
STEM CELLS (2010)
Integrins in cancer: biological implications and therapeutic opportunities
Jay S. Desgrosellier et al.
NATURE REVIEWS CANCER (2010)
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Kandice R. Levental et al.
CELL (2009)
Cancer-associated fibroblasts and tumor growth - bystanders turning into key players
Arne Oestman et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
Kindlin-1 and-2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects
David S. Harburger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Integrin signalling at a glance
David S. Harburger et al.
JOURNAL OF CELL SCIENCE (2009)
Environmental sensing through focal adhesions
Benjamin Geiger et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Mechanotransduction gone awry
Diana E. Jaalouk et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Podoplanin Expression Identified in Stromal Fibroblasts as a Favorable Prognostic Marker in Patients with Colorectal Carcinoma
Takahiro Yamanashi et al.
ONCOLOGY (2009)
Micro-Environmental Mechanical Stress Controls Tumor Spheroid Size and Morphology by Suppressing Proliferation and Inducing Apoptosis in Cancer Cells
Gang Cheng et al.
PLOS ONE (2009)
The role of matrix stiffness in regulating cell behavior
Rebecca G. Wells
HEPATOLOGY (2008)
Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma
Akikazu Kawase et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration
Vishnu V. Undyala et al.
JOURNAL OF CELL SCIENCE (2008)
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Cedric Gaggioli et al.
NATURE CELL BIOLOGY (2007)
Prostate cancer specific integrin αvβ3 modulates bone metastatic growth and tissue remodeling
N. P. McCabe et al.
ONCOGENE (2007)
Integrin all regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
Chang-Qi Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Tumor microenvironment: The role of the tumor stroma in cancer
Hanchen Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samples
Abbas Samani et al.
PHYSICS IN MEDICINE AND BIOLOGY (2007)
The tumour microenvironment as a target for chemoprevention
Adriana Albini et al.
NATURE REVIEWS CANCER (2007)
The integrins
Yoshikazu Takada et al.
GENOME BIOLOGY (2007)
Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer
B. S. M. S. Siriwardena et al.
BRITISH JOURNAL OF CANCER (2006)
How the headpiece hinge angle is opened: new insights into the dynamics of integrin activation
Eileen Puklin-Faucher et al.
JOURNAL OF CELL BIOLOGY (2006)
Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation
Wei Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Periostin: A novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
Go Takayama et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Rigidity sensing at the leading edge through αvβ3 Integrins and RPTPα
GY Jiang et al.
BIOPHYSICAL JOURNAL (2006)
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts
MD Amatangelo et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Laminin-induced signaling in tumor cells
V Givant-Horwitz et al.
CANCER LETTERS (2005)
Regulating cell migration: calpains make the cut
SJ Franco et al.
JOURNAL OF CELL SCIENCE (2005)
Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway
SD Bao et al.
CANCER CELL (2004)
Lack of integrin α1β1 leads to severe glomerulosclerosis after glomerular injury
XW Chen et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Stromal fibroblasts in cancer initiation and progression
NA Bhowmick et al.
NATURE (2004)
Molecular basis for the dynamic strength of the integrin α4β1/VCAM-1 interaction
XH Zhang et al.
BIOPHYSICAL JOURNAL (2004)
Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression
R Shao et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Talin binding to integrin β tails:: A final common step in integrin activation
S Tadokoro et al.
SCIENCE (2003)
Mechanisms of force generation and transmission by myofibroblasts
B Hinz et al.
CURRENT OPINION IN BIOTECHNOLOGY (2003)
Integrin αvβ3 as a therapeutic target for blocking tumor-induced angiogenesis
CC Kumar
CURRENT DRUG TARGETS (2003)
Novel candidate tumor marker genes for lung adenocarcinoma
K Wang et al.
ONCOGENE (2002)
Integrins: Bidirectional, allosteric signaling machines
RO Hynes
CELL (2002)
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
J Takagi et al.
CELL (2002)
Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand
JP Xiong et al.
SCIENCE (2002)
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
E Tzima et al.
EMBO JOURNAL (2001)
Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation
B Hinz et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Integrin activation controls metastasis in human breast cancer
B Felding-Habermann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Ligand binding to integrins
EF Plow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The collagen-binding A-domains of integrins α1β1 and α2β1 recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens
CG Knight et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)