Journal
JOURNAL OF CLINICAL MEDICINE
Volume 8, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/jcm8020182
Keywords
phantom limb; somatotopy; brachial plexus; deafferentation rehabilitation; anesthetic block
Categories
Funding
- International Foundation for Research in Paraplegie [P133]
- EU Information and Communication Technologies Grant [VERE project] [FP7-ICT-2009-5, 257695]
- ANIA Foundation
- Sapienza University of Rome
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Many neuropsychological theories agree that the brain maintains a relatively persistent representation of one's own body, as indicated by vivid phantom experiences. It remains unclear how the loss of sensory and motor information contributes to the presence of this representation. Here, we focus on new empirical and theoretical evidence of phantom sensations following damage to or an anesthetic block of the brachial plexus. We suggest a crucial role of this structure in understanding the interaction between peripheral and central mechanisms in health and in pathology. Studies of brachial plexus function have shed new light on how neuroplasticity enables somatotopic interferences, including pain and body awareness. Understanding the relations among clinical disorders, their neural substrate, and behavioral outcomes may enhance methods of sensory rehabilitation for phantom limbs.
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