Journal
ABDOMINAL RADIOLOGY
Volume 44, Issue 6, Pages 1960-1984Publisher
SPRINGER
DOI: 10.1007/s00261-019-02028-w
Keywords
Radiomics; Quantitative imaging; Radiogenomics; Genomics; Brain neoplasms; Lung neoplasms; Breast neoplasms; Kidney neoplasms; Liver neoplasms; Colorectal neoplasms; Prostate neoplasms
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From diagnostics to prognosis to response prediction, new applications for radiomics are rapidly being developed. One of the fastest evolving branches involves linking imaging phenotypes to the tumor genetic profile, a field commonly referred to as radiogenomics. In this review, a general outline of radiogenomic literature concerning prominent mutations across different tumor sites will be provided. The field of radiogenomics originates from image processing techniques developed decades ago; however, many technical and clinical challenges still need to be addressed. Nevertheless, increasingly accurate and robust radiogenomic models are being presented and the future appears to be bright.
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