4.7 Review

Melatonin Synthesis and Function: Evolutionary History in Animals and Plants

Related references

Note: Only part of the references are listed.
Article Food Science & Technology

Anti-inflammatory effects of Melatonin: A mechanistic review

Seyed Mohammad Nabavi et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2019)

Review Cell Biology

Melatonin, a toll-like receptor inhibitor: Current status and future perspectives

Omid Reza Tamtaji et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Pharmacology & Pharmacy

Is There Sufficient Evidence that the Melatonin Binding Site MT3 Is Quinone Reductase 2?

Jean A. Boutin et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2019)

Review Pharmacology & Pharmacy

Docking studies for melatonin receptors

Hanan Awad Alkozi et al.

EXPERT OPINION ON DRUG DISCOVERY (2018)

Article Biochemistry & Molecular Biology

Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism

Jason R. Treberg et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Oxidative stress and neurodegeneration: The possible contribution of quinone reductase 2

Laure-Estelle Cassagnes et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Article Endocrinology & Metabolism

Phytomelatonin receptor PMTR1-mediated signaling regulates stomatal closure in Arabidopsis thaliana

Jian Wei et al.

JOURNAL OF PINEAL RESEARCH (2018)

Review Endocrinology & Metabolism

Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

Annia Galano et al.

JOURNAL OF PINEAL RESEARCH (2018)

Article Endocrinology & Metabolism

LIM homeobox transcription factor Isl1 is required for melatonin synthesis in the pig pineal gland

Jinglin Zhang et al.

JOURNAL OF PINEAL RESEARCH (2018)

Review Endocrinology & Metabolism

Melatonin and cardioprotection against ischaemia/reperfusion injury: What's new? A review

Amanda Lochner et al.

JOURNAL OF PINEAL RESEARCH (2018)

Review Biochemistry & Molecular Biology

Melatonin: A Molecule for Reducing Breast Cancer Risk

Alicia Gonzalez-Gonzalez et al.

MOLECULES (2018)

Review Biochemistry & Molecular Biology

Melatonin: A Versatile Protector against Oxidative DNA Damage

Annia Galano et al.

MOLECULES (2018)

Review Cell Biology

The role of melatonin, a multitasking molecule, in retarding the processes of ageing

Maryam Majidinia et al.

AGEING RESEARCH REVIEWS (2018)

Review Biochemistry & Molecular Biology

Mechanisms Underlying Tumor Suppressive Properties of Melatonin

Stephen C. Bondy et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

Russel J. Reiter et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

The Role of Phyto-Melatonin and Related Metabolites in Response to Stress

Yang Yu et al.

MOLECULES (2018)

Review Endocrinology & Metabolism

Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers

Javier Menendez-Menendez et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2018)

Review Endocrinology & Metabolism

Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin's roles in prophylaxis and management

Adejoke Y. Onaolapo et al.

WORLD JOURNAL OF DIABETES (2018)

Article Pharmacology & Pharmacy

Immune-pineal axis - acute inflammatory responses coordinate melatonin synthesis by pinealocytes and phagocytes

Regina P. Markus et al.

BRITISH JOURNAL OF PHARMACOLOGY (2018)

Review Endocrinology & Metabolism

Cancer metastasis: Mechanisms of inhibition by melatonin

Shih-Chi Su et al.

JOURNAL OF PINEAL RESEARCH (2017)

Article Endocrinology & Metabolism

Melatonin is required for H2O2- and NO-mediated defense signaling through MAPKKK3 and OXI1 in Arabidopsis thaliana

Hyoung Yool Lee et al.

JOURNAL OF PINEAL RESEARCH (2017)

Article Agriculture, Multidisciplinary

Natural Variation in Banana Varieties Highlights the Role of Melatonin in Postharvest Ripening and Quality

Wei Hu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Article Chemistry, Medicinal

Role of Reactive Oxygen Species (ROS) in Therapeutics and Drug Resistance in Cancer and Bacteria

Allimuthu T. Dharmaraja

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Chemistry, Physical

Low-Energy Electron Interaction with Melatonin and Related Compounds

Stanislav A. Pshenichnyuk et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2017)

Article Endocrinology & Metabolism

HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants

Shu-Yu Cai et al.

JOURNAL OF PINEAL RESEARCH (2017)

Article Endocrinology & Metabolism

Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress

Lin Wang et al.

JOURNAL OF PINEAL RESEARCH (2017)

Article Endocrinology & Metabolism

Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function

Miguel Mendivil-Perez et al.

JOURNAL OF PINEAL RESEARCH (2017)

Review Endocrinology & Metabolism

Melatonin and sirtuins: A not-so unexpected relationship

Juan C. Mayo et al.

JOURNAL OF PINEAL RESEARCH (2017)

Review Biochemistry & Molecular Biology

Taxon- and Site-Specific Melatonin Catabolism

Ruediger Hardeland

MOLECULES (2017)

Article Multidisciplinary Sciences

Biological regulation of atmospheric chemistry en route to planetary oxygenation

Gareth Izon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

Yalikun Suofu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Daily corticosterone rhythm modulates pineal function through NFκB-related gene transcriptional program

Sanseray da Silveira Cruz-Machado et al.

SCIENTIFIC REPORTS (2017)

Article Plant Sciences

Melatonin Regulates Root Architecture by Modulating Auxin Response in Rice

Chengzhen Liang et al.

FRONTIERS IN PLANT SCIENCE (2017)

Review Immunology

Melatonin as an anti-inflammatory agent in radiotherapy

M. Najafi et al.

INFLAMMOPHARMACOLOGY (2017)

Article Multidisciplinary Sciences

Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress

Xiaodong Zheng et al.

SCIENTIFIC REPORTS (2017)

Article Endocrinology & Metabolism

The hormone melatonin: Animal studies

P. Pevet et al.

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2017)

Review Biochemistry & Molecular Biology

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

Russel J. Reiter et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Review Immunology

Mitochondrial control of immunity: beyond ATP

Manan M. Mehta et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Review Pharmacology & Pharmacy

Quinone reductase 2 as a promising target of melatonin therapeutic actions

Jean A. Boutin

EXPERT OPINION ON THERAPEUTIC TARGETS (2016)

Article Endocrinology & Metabolism

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons

Abla Benleulmi-Chaachoua et al.

JOURNAL OF PINEAL RESEARCH (2016)

Review Pharmacology & Pharmacy

MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective

Jiabei Liu et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)

Review Pharmacology & Pharmacy

Update on melatonin receptors: IUPHAR Review 20

Ralf Jockers et al.

BRITISH JOURNAL OF PHARMACOLOGY (2016)

Article Endocrinology & Metabolism

Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells

Carlos Quintana et al.

JOURNAL OF PINEAL RESEARCH (2016)

Article Endocrinology & Metabolism

Melatonin mediates selenium-induced tolerance to cadmium stress in tomato plants

Meng-Qi Li et al.

JOURNAL OF PINEAL RESEARCH (2016)

Review Endocrinology & Metabolism

Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts

Kyoungwhan Back et al.

JOURNAL OF PINEAL RESEARCH (2016)

Article Endocrinology & Metabolism

Molecular cloning of melatonin 3-hydroxylase and its production of cyclic 3-hydroxymelatonin in rice (Oryza sativa)

Kyungjin Lee et al.

JOURNAL OF PINEAL RESEARCH (2016)

Review Endocrinology & Metabolism

Melatonin as an antioxidant: under promises but over delivers

Russel J. Reiter et al.

JOURNAL OF PINEAL RESEARCH (2016)

Review Plant Sciences

Fundamental Issues of Melatonin-Mediated Stress Signaling in Plants

Haitao Shi et al.

FRONTIERS IN PLANT SCIENCE (2016)

Review Plant Sciences

Melatonin in Plants - Diversity of Levels and Multiplicity of Functions

Ruediger Hardeland

FRONTIERS IN PLANT SCIENCE (2016)

Article Multidisciplinary Sciences

Rapid oxygenation of Earth's atmosphere 2.33 billion years ago

Genming Luo et al.

SCIENCE ADVANCES (2016)

Editorial Material Biochemistry & Molecular Biology

Circadian Clocks: Unexpected Biochemical Cogs

Tetsuya Mori et al.

CURRENT BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Endosymbiosis and Eukaryotic Cell Evolution

John M. Archibald

CURRENT BIOLOGY (2015)

Article Cell Biology

Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

Lei Shi et al.

CURRENT OPINION IN CELL BIOLOGY (2015)

Review Oncology

Melatonin: an inhibitor of breast cancer

Steven M. Hill et al.

ENDOCRINE-RELATED CANCER (2015)

Review Endocrinology & Metabolism

Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals

Lance J. Kriegsfeld et al.

FRONTIERS IN NEUROENDOCRINOLOGY (2015)

Review Endocrinology & Metabolism

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

Lucien C. Manchester et al.

JOURNAL OF PINEAL RESEARCH (2015)

Review Endocrinology & Metabolism

Functions of melatonin in plants: a review

Marino B. Arnao et al.

JOURNAL OF PINEAL RESEARCH (2015)

Review Biochemistry & Molecular Biology

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

Dun-Xian Tan et al.

MOLECULES (2015)

Review Biochemistry & Molecular Biology

Phytomelatonin: Assisting Plants to Survive and Thrive

Russel J. Reiter et al.

MOLECULES (2015)

Article Clinical Neurology

Melatonin: Physiological effects in humans

B. Claustrat et al.

NEUROCHIRURGIE (2015)

Review Plant Sciences

Melatonin in plants and other phototrophs: advances and gaps concerning the diversity of functions

Ruediger Hardeland

JOURNAL OF EXPERIMENTAL BOTANY (2015)

Review Plant Sciences

Roles of melatonin in abiotic stress resistance in plants

Na Zhang et al.

JOURNAL OF EXPERIMENTAL BOTANY (2015)

Article Biochemistry & Molecular Biology

Melatonin Signaling Controls Circadian Swimming Behavior in Marine Zooplankton

Maria Antonietta Tosches et al.

Review Biochemistry & Molecular Biology

Fundamental Issues Related to the Origin of Melatonin and Melatonin Isomers during Evolution: Relation to Their Biological Functions

Dun-Xian Tan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

Melatonin as a Signaling Molecule for Metabolism Regulation in Response to Hypoxia in the Crab Neohelice granulata

Fabio Everton Maciel et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Endocrinology & Metabolism

Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT

Yeong Byeon et al.

JOURNAL OF PINEAL RESEARCH (2014)

Article Endocrinology & Metabolism

Elevated production of melatonin in transgenic rice seeds expressing rice tryptophan decarboxylase

Yeong Byeon et al.

JOURNAL OF PINEAL RESEARCH (2014)

Review Physiology

Melatonin: Exceeding Expectations

Russel J. Reiter et al.

PHYSIOLOGY (2014)

Article Multidisciplinary Sciences

Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya

Jack Falcon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Pharmacology & Pharmacy

Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review

Mariano Bizzarri et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2013)

Article Chemistry, Applied

Growth conditions influence the melatonin content of tomato plants

Marino Banon Arnao et al.

FOOD CHEMISTRY (2013)

Review Biochemistry & Molecular Biology

Immune-Pineal Axis: Nuclear Factor κB (NF-κB) Mediates the Shift in the Melatonin Source from Pinealocytes to Immune Competent Cells

Regina P. Markus et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Clinical Neurology

Alterations of melatonin receptors MT1 and MT2 in the hypothalamic suprachiasmatic nucleus during depression

Ying-Hui Wu et al.

JOURNAL OF AFFECTIVE DISORDERS (2013)

Article Endocrinology & Metabolism

Molecular cloning of rice serotonin N-acetyltransferase, the penultimate gene in plant melatonin biosynthesis

Kiyoon Kang et al.

JOURNAL OF PINEAL RESEARCH (2013)

Article Endocrinology & Metabolism

Melatonin-rich transgenic rice plants exhibit resistance to herbicide-induced oxidative stress

Sangkyu Park et al.

JOURNAL OF PINEAL RESEARCH (2013)

Review Endocrinology & Metabolism

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

Annia Galano et al.

JOURNAL OF PINEAL RESEARCH (2013)

Article Endocrinology & Metabolism

Growth conditions determine different melatonin levels in Lupinus albus L.

Marino B. Arnao et al.

JOURNAL OF PINEAL RESEARCH (2013)

Article Chemistry, Medicinal

The Universal Nature, Unequal Distribution and Antioxidant Functions of Melatonin and Its Derivatives

Russel J. Reiter et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2013)

Review Biochemistry & Molecular Biology

Molecular mechanisms of photodamage in the Photosystem II complex

Imre Vass

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)

Review Plant Sciences

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science

Dun-Xian Tan et al.

JOURNAL OF EXPERIMENTAL BOTANY (2012)

Article Endocrinology & Metabolism

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

Carmen Venegas et al.

JOURNAL OF PINEAL RESEARCH (2012)

Review Cell Biology

Melatonin membrane receptors in peripheral tissues: Distribution and functions

Radomir M. Slominski et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)

Editorial Material Endocrinology & Metabolism

Naughty Melatonin: How Mothers Tick Off their Fetus

Valerie Simonneaux

ENDOCRINOLOGY (2011)

Article Biochemistry & Molecular Biology

Insights into the redox cycle of human quinone reductase 2

Karine Reybier et al.

FREE RADICAL RESEARCH (2011)

Article Endocrinology & Metabolism

Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice

Kiyoon Kang et al.

JOURNAL OF PINEAL RESEARCH (2011)

Article Endocrinology & Metabolism

Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)

Anna Leja-Szpak et al.

JOURNAL OF PINEAL RESEARCH (2010)

Article Nutrition & Dietetics

Melatonin in Plants

Russel J. Reiter et al.

NUTRITION REVIEWS (2010)

Article Biochemistry & Molecular Biology

Melatonin: Signaling mechanisms of a pleiotropic agent

Ruediger Hardeland

BIOFACTORS (2009)

Article Biochemistry & Molecular Biology

MT2-like melatonin receptor modulates amplitude receptor potential in visual cells of crayfish during a 24-hour cycle

Leonor Mendoza-Vargas et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2009)

Article Oncology

Molecular Mechanisms of Melatonin Anticancer Effects

Steven M. Hill et al.

INTEGRATIVE CANCER THERAPIES (2009)

Review Endocrinology & Metabolism

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

Ruediger Hardeland et al.

JOURNAL OF PINEAL RESEARCH (2009)

Review Biochemistry & Molecular Biology

Melatonin: An Established Antioxidant Worthy of Use in Clinical Trials

Ahmet Korkmaz et al.

MOLECULAR MEDICINE (2009)

Review Microbiology

Oxidative stress in cyanobacteria

Amel Latifi et al.

FEMS MICROBIOLOGY REVIEWS (2009)

Article Biochemistry & Molecular Biology

Studies of the melatonin binding site location onto quinone reductase 2 by directed mutagenesis

Jean A. Boutin et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)

Article Biochemistry & Molecular Biology

Conversion of 5-hydroxytryptophan into serotonin by tryptophan decarboxylase in plants, Escherichia coli, and yeast

Munyoung Park et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)

Review Pharmacology & Pharmacy

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

R. Jockers et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Review Biochemistry & Molecular Biology

Melatonin, hormone of darkness and more - occurrence, control mechanisms, actions and bioactive metabolites

R. Hardeland

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Cell Biology

Rhythmic control of AANAT translation by hnRNP Q in circadian melatonin production

Tae-Don Kim et al.

GENES & DEVELOPMENT (2007)

Review Biochemistry & Molecular Biology

Arylalkylamine N-acetyltransferase:: the timezyme

David C. Klein

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Cell Biology

Evolution of arylalkylamine N-acetyltransferase:: Emergence and divergence

Steven L. Coon et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2006)

Article Biology

Evolution of the vertebrate pineal gland: The AANAT hypothesis

DC Klein

CHRONOBIOLOGY INTERNATIONAL (2006)

Review Endocrinology & Metabolism

Melatonin in higher plants:: occurrence and possible functions

J Kolár et al.

JOURNAL OF PINEAL RESEARCH (2005)

Article Endocrinology & Metabolism

N-acetyltransferase is not the rate-limiting enzyme of melatonin synthesis at night

TC Liu et al.

JOURNAL OF PINEAL RESEARCH (2005)

Review Clinical Neurology

The basic physiology and pathophysiology of melatonin

B Claustrat et al.

SLEEP MEDICINE REVIEWS (2005)

Article Multidisciplinary Sciences

Melatonin synthesis:: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205

S Ganguly et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Endocrinology & Metabolism

Melatonin mitigates mitochondrial malfunction

J Leon et al.

JOURNAL OF PINEAL RESEARCH (2005)

Review Endocrinology & Metabolism

Relationship between stress, inflammation and metabolism

G Seematter et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2004)

Article Biochemistry & Molecular Biology

A genome phylogeny for mitochondria among α-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes

C Esser et al.

MOLECULAR BIOLOGY AND EVOLUTION (2004)

Article Endocrinology & Metabolism

Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin

DX Tan et al.

JOURNAL OF PINEAL RESEARCH (2003)

Review Biochemistry & Molecular Biology

Mitochondrial ROS metabolism:: Modulation by uncoupling proteins

L Casteilla et al.

IUBMB LIFE (2001)

Review Endocrinology & Metabolism

Melatonin, mitochondria, and cellular bioenergetics

D Acuña-Castroviejo et al.

JOURNAL OF PINEAL RESEARCH (2001)

Review Microbiology

Origin and evolution of the mitochondrial proteome

CG Kurland et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2000)

Article Medicine, Research & Experimental

High levels of melatonin in the seeds of edible plants - Possible function in germ tissue protection

LC Manchester et al.

LIFE SCIENCES (2000)

Article Biochemistry & Molecular Biology

Characterization of the chicken serotonin N-acetyltransferase gene -: Activation via clock gene heterodimer/e box interaction

NW Chong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)