Journal
FRONTIERS IN PHYSIOLOGY
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fphys.2019.00516
Keywords
chitosan; chito-oligosaccharides; biological activity; application; microbiota
Categories
Funding
- China Scholarship Council [201708430008]
- National Natural Science Foundation of China [31402092, 31772642, 31872991]
- Scientific Research Fund of Hunan Provincial Education Department [17K043, 16A096]
- Hunan Provincial Natural Science Foundation of China [2018JJ1012]
- Hunan Provincial Science and Technology Department [2017NK2322, 2018RS3086]
- National Key Research and Development Program of China [2016YFD0500504, 2016YFD0501201]
- International Partnership Program of the Chinese Academy of Sciences [161343KYSB20160008]
- Double first-class construction project of Hunan Agricultural University [SYL201802002]
- Science and Technology Department of Changsha [kq1706025]
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The numerous functional properties and biological effects of chitosan and chito-oligosaccharides (COS) have led to a significant level of interest, particularly with regard to their potential use in the agricultural, environmental, nutritional, and pharmaceutical fields. This review covers recent studies on the biological functions of COS and the impacts of dietary chitosan and COS on metabolism. The majority of results suggest that the use of chitosan as a feed additive has favorable biological effects, such as antimicrobial, anti-oxidative, cholesterol reducing, and immunomodulatory effects. The biological impacts reviewed herein may provide a new appreciation for the future use of COS.
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