4.4 Article

Lyapunov functions and global stability for a spatially diffusive SIR epidemic model

Journal

APPLICABLE ANALYSIS
Volume 96, Issue 11, Pages 1935-1960

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/00036811.2016.1199796

Keywords

SIR epidemic model; Lyapunov function; diffusion; basic reproduction number

Funding

  1. Japan Society for the Promotion of Science [15K17585]
  2. Japan Initiative for Global Research Network on Infectious Diseases (J-GRID)
  3. Japan Agency for Medical Research and Development, AMED
  4. National Natural Science Foundation of China [11401182, 11471089]
  5. Science and Technology Innovation Team in Higher Education Institutions of Heilongjiang Province [2014TD005]
  6. Youth Innovation Talents ofHeilongjiang Education Department
  7. Grants-in-Aid for Scientific Research [15K17585] Funding Source: KAKEN

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This paper deals with the problem of global asymptotic stability for equilibria of a spatially diffusive SIR epidemic model with homogeneous Neumann boundary condition. By discretizing the model with respect to the space variable, we first construct Lyapunov functions for the corresponding ODEs model, and then broaden the construction method into the PDEs model in which either susceptible or infective populations are diffusive. In both cases, we obtain the standard threshold dynamical behaviors, that is, if R-0 <= 1, then the disease-free equilibrium is globally asymptotically stable and if R-0 > 1, then the (strictly positive) endemic equilibrium is so. Numerical examples are given to illustrate the effectiveness of the theoretical results.

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