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Chemistry, pharmacology and analysis of Pseudostellaria heterophylla: a mini-review

Journal

CHINESE MEDICINE
Volume 14, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s13020-019-0243-z

Keywords

Pseudostellaria heterophylla; Chemistry; Pharmacology; Analysis

Funding

  1. National Natural Science Foundation of China [81673389, 81603069]
  2. Science and Technology Development Fund of Macau [074/2016/A2, 075/2018/A2, 034/2017/A1, 040/2016/A]
  3. University of Macau [MYRG2018-00083, CPG2019-00027]

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Pseudostellaria heterophylla is one of the well-known traditional Chinese medicines and has been used in clinics for 100years in China. The chemistry and pharmacology of P. heterophylla were reviewed to understand its active compounds. Then analysis of these compounds related to quality control of this herb was discussed. For the analysis of chemicals, three aspects have been discussed in this review. The first two aspects focused on the methodologies for analysis of cyclic peptides and carbohydrates in P. heterophylla, respectively. The last one dealt with the other methods used for identification of P. heterophylla. Some rich chemicals such as oligosaccharides in this plant were rarely evaluated. Many analyses were performed on this plant, however, few of them were accepted as quality control method.

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