Journal
BIOMEDICAL OPTICS EXPRESS
Volume 10, Issue 5, Pages 2556-2579Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.10.002556
Keywords
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Funding
- European Commission Competitiveness for Innovation Program (An optical neuro-monitor of cerebral oxygen metabolism and blood flow for neonatology (BabyLux)) [620996]
- Fundacio CELLEX Barcelona
- Ministerio de Economia y Competitividad / FEDER (PHOTODEMENTIA) [DPI2015-64358-C2-1-R]
- Instituto de Salud CarlosIII / FEDER (MEDPHOTAGE) [DTS16/00087]
- Obra social la Caixa Foundation (LlumMedBcn)
- Institucio CERCA
- AGAUR-Generalitat [2017 SGR 1380]
- LASERLAB-EUROPE IV
- Severo Ochoa Programme for Centres of Excellence in RD [SEV-2015-0522]
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We have investigated the accuracy and precision of the BabyLux device, a hybrid time-resolved near-infrared (TRS) and diffuse correlation spectroscopy (DCS) neuro-monitor for the pre-term infant. Numerical data with realistic noise were simulated and analyzed using the BabyLux device as a reference system and different experimental and analysis parameters. The results describe the limits for the precision and the accuracy to be expected. The dependence of these limits on different experimental conditions and choices of the analysis method is also described. Experiments demonstrate comparable values for precision with respect to the simulation results. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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