4.7 Article

Outbreak of OXA-48-Producing Klebsiella pneumoniae Involving a Sequence Type 101 Clone in Batna University Hospital, Algeria

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 60, Issue 12, Pages 7494-7497

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00525-16

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Funding

  1. Centre National de la Recherche Scientifique [CNRS7278]
  2. IHU Mediterranee Infection

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Seven nonredundant ertapenem-resistant Klebsiella pneumoniae isolates were collected between May 2014 and 19 January 2015 in the nephrology and hematology units of Batna University Hospital in Algeria. All strains coproduced the bla(OXA-48), bla(CTX-M-15), bla(SHV-1), and bla(TEM-1D) genes. Six of these isolates belonged to the pandemic clone sequence type 101 (ST101). The bla(OXA-48) gene was located on a conjugative IncL/M-type plasmid. This is the first known outbreak of OXA-48-producing K. pneumoniae isolates involving an ST101 clone in Batna University Hospital.

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