Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 60, Issue 9, Pages 5589-5591Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00935-16
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Here, we present the full sequences of three mcr-1-carrying plasmids isolated from extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli. The plasmids belong to three different replicon types and are 34,640 bp, 209,401 bp, and 247,885 bp in size. We describe for the first time a composite transposon containing mcr-1 localized on a multidrug-resistant (MDR) IncHI2 plasmid harboring additional determinants of resistance to six different classes of antibiotics, including the ESBL gene bla(CTX-M-1), and heavy metal resistance.
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