4.6 Editorial Material

Oxysterol Binding Protein: Tether, Transporter ... and Flux Capacitor?

Journal

TRENDS IN CELL BIOLOGY
Volume 29, Issue 7, Pages 531-533

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2019.04.004

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Funding

  1. NIGMS NIH HHS [R35 GM119412] Funding Source: Medline

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The oxysterol binding protein (OSBP) is a storied protein in organelle biology. Its early roles include acting as a membrane contact site (MCS) tether as well as a lipid antiporter. A surprising new function for OSBP in MCS dynamics has now been uncovered in a recent study by Jamecna et al. (Dev. Cell 2019; 49: 220-234).

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