Journal
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Volume 16, Issue 10, Pages 1339-1352Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1871520616666160622090839
Keywords
Cancer; drug discovery; synthesis; quinoxaline; heterocyclic compounds; biological activity
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Heterocyclic compounds are a class of substances, which play a critical role in modern drug discovery being incorporated in the structure of a large variety of drugs used in many different types of diseases. Quinoxaline is an important heterocyclic nucleus with a wide spectrum of biological activities, and recently much attention has been found on anticancer drug discovery based on this class. Owing to the importance of this system, the aim of this review is to provide an update on the synthesis and anticancer activity of quinoxaline derivatives covering articles published between 2010 and 2015.
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