4.4 Article

Recent advances in indoline synthesis

Journal

TETRAHEDRON
Volume 75, Issue 14, Pages 2063-2097

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.02.006

Keywords

Indolines; Heterocycles; Transition metals; Organocatalysis; Cyclizations

Funding

  1. Sao Paulo Foundation for Science (FAPESP) [2018/02611-0, 2013/07600-3]
  2. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brasil (CAPES) [001]
  3. Brazilian National Council for Science and Development (CNPq) [307840/2014-0]
  4. FAPESP [2016/23005-6, 2015/09205-0]
  5. CAPES
  6. CNPq
  7. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [13/07600-3] Funding Source: FAPESP

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Indoline is an important structural motif present in several biologically active compounds from both natural and synthetic origins. The occurrence of this heterocyclic unity in these compounds is closely related to the biological activities they exhibit. This fact stimulated efforts that have been made worldwide to develop new synthetic approaches to prepare indolines. In this paper we reviewed critically the methods for indoline synthesis developed in the last years (from 2010 to 2018). (C) 2019 Elsevier Ltd. All rights reserved.

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