4.4 Article

Electrochemical Deoxygenation of N-Heteroaromatic N-Oxides

Journal

SYNLETT
Volume 30, Issue 10, Pages 1219-1221

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1611541

Keywords

reduction; organic electrosynthesis; deoxygenation; electrolysis; heterocycles

Funding

  1. Ministry of Science and Technology of the People's Republic of China (MOST) [2016YFA0204100]
  2. the National Natural Science Foundation of China (NSFC) [21672178]
  3. Fundamental Research Funds for the Central Universities

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An electrochemical method for the deoxygenation of N-heteroaromatic N -oxide to give the corresponding N-heteroaromatics has been developed. Several classes of N-heterocycles such as pyridine, quinoline, isoquinoline, and phenanthridine are tolerated. The electrochemical reactions proceed efficiently in aqueous solution without the need for transition-metal catalysts and waste-generating reducing reagents.

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