Journal
SYNLETT
Volume 30, Issue 8, Pages 924-927Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1611805
Keywords
marine natural products; peptides; polyketides; beta-ketoamide; asymmetric aldol reaction
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Funding
- JSPS KAKENHI [17H01523, 18H04399]
- Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research
- BINDS) from the Japan Agency for Medical Research and Development (AMED) [JP18am0101099]
- Grants-in-Aid for Scientific Research [18H04399, 17H01523] Funding Source: KAKEN
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The synthesis of two marine lipodipeptides, majusculamides A and B, is described. The key feature of this synthesis is the stereoselective construction of an alpha- methyl-beta-keto-carboxamide moiety.
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