Journal
SLEEP
Volume 42, Issue 8, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/sleep/zsz113
Keywords
individual differences; sleep restriction; circadian misalignment; performance; Maintenance of Wakefulness Test; sex differences
Categories
Funding
- Office of Naval Research MURI grant [N00014-15-1-2809]
- NIH/NCATS Colorado CTSA Grant [UL1TR002535]
- University of Colorado Boulder
Ask authors/readers for more resources
Study Objectives: Determine stability of individual differences in executive function, cognitive processing speed, selective visual attention, and maintenance of wakefulness during simulated sustained operations with combined sleep restriction and circadian misalignment. Methods: Twenty healthy adults (eight female), aged 25.7 (+/- 4.2 SD), body mass index (BMI) 22.3 (+/- 2.1) kg/m(2) completed an 18-day protocol twice. Participants maintained habitual self-selected 8-hour sleep schedules for 2 weeks at home prior to a 4-day laboratory visit that included one sleep opportunity per day: 8 hours on night 1, 3 hours on night 2, and 3 hours on mornings 3 and 4. After 3 days of unscheduled sleep at home, participants repeated the entire protocol. Stability and task dependency of individual differences in performance were quantified by intra-class correlation coefficients (ICC) and Kendall's Tau, respectively. Results: Performance on Stroop, Visual Search, and the Maintenance of Wakefulness Test were highly consistent within individuals during combined sleep restriction and circadian misalignment. Individual differences were trait-like as indicated by ICCs (0.54-0.96) classified according to standard criteria as moderate to almost perfect. Individual differences on other performance tasks commonly reported in sleep studies showed fair to almost perfect ICCs (0.22-0.94). Kendall's rank correlations showed that individual vulnerability to sleep restriction and circadian misalignment varied by task and by metric within a task. Conclusions: Consistent vulnerability of higher-order cognition and maintenance of wakefulness to combined sleep restriction and circadian misalignment has implications for the development of precision countermeasure strategies for workers performing safety-critical tasks, e.g. military, police, health care workers and emergency responders.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available