4.8 Article

SYNTHETIC BIOLOGY A compact synthetic pathway rewires cancer signaling to therapeutic effector release

Related references

Note: Only part of the references are listed.
Review Oncology

Emerging functions of the EGFR in cancer

Sara Sigismund et al.

MOLECULAR ONCOLOGY (2018)

Article Oncology

Targeting the Gatekeeper: Osimertinib in EGFR T790M Mutation-Positive Non-Small Cell Lung Cancer

Ferdinandos Skoulidis et al.

CLINICAL CANCER RESEARCH (2017)

Article Biochemistry & Molecular Biology

Rewiring human cellular input-output using modular extracellular sensors

Kelly A. Schwarz et al.

NATURE CHEMICAL BIOLOGY (2017)

Article Biotechnology & Applied Microbiology

A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

Wenjing Wang et al.

NATURE BIOTECHNOLOGY (2017)

Review Oncology

Review: Oncolytic virotherapy, updates and future directions

Christos Fountzilas et al.

ONCOTARGET (2017)

Article Biochemistry & Molecular Biology

Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy

Lior Nissim et al.

Review Biochemical Research Methods

Advancing therapeutic applications of synthetic gene circuits

Yasutomi Higashikuni et al.

CURRENT OPINION IN BIOTECHNOLOGY (2017)

Review Biochemistry & Molecular Biology

Mammalian synthetic biology in the age of genome editing and personalized medicine

Patrick Ho et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2017)

Review Oncology

Adeno-Associated Virus (AAV) as a Vector for Gene Therapy

Michael F. Naso et al.

BIODRUGS (2017)

Article Biochemistry & Molecular Biology

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Leonardo Morsut et al.

Article Biotechnology & Applied Microbiology

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench et al.

NATURE BIOTECHNOLOGY (2016)

Article Medicine, General & Internal

Weekly vs. Every-3-Week Paclitaxel for Ovarian Cancer

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Review Immunology

ErbB-targeted CAR T-cell immunotherapy of cancer

Lynsey M. Whilding et al.

IMMUNOTHERAPY (2015)

Article Multidisciplinary Sciences

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Silvana Konermann et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Tunable and reversible drug control of protein production via a self-excising degron

Hokyung K. Chung et al.

NATURE CHEMICAL BIOLOGY (2015)

Article Biochemical Research Methods

Highly efficient Cas9-mediated transcriptional programming

Alejandro Chavez et al.

NATURE METHODS (2015)

Review Biochemistry & Molecular Biology

Synthetic therapeutic gene circuits in mammalian cells

Haifeng Ye et al.

FEBS LETTERS (2014)

Review Microbiology

New viruses for cancer therapy: meeting clinical needs

Tanner S. Miest et al.

NATURE REVIEWS MICROBIOLOGY (2014)

Review Cell Biology

Synthetic biology in mammalian cells: next generation research tools and therapeutics

Florian Lienert et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Architecture and Membrane Interactions of the EGF Receptor

Anton Arkhipov et al.

Article Oncology

EGFR and HER2 inhibition in pancreatic cancer

Naomi Walsh et al.

INVESTIGATIONAL NEW DRUGS (2013)

Article Biotechnology & Applied Microbiology

DARPin-targeting of Measles Virus: Unique Bispecificity, Effective Oncolysis, and Enhanced Safety

Katrin Friedrich et al.

MOLECULAR THERAPY (2013)

Article Multidisciplinary Sciences

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

Yong Zheng et al.

NATURE (2013)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Article Multidisciplinary Sciences

Fast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane

Dongmyung Oh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Medicine, Research & Experimental

Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils

Davide Torti et al.

EMBO MOLECULAR MEDICINE (2011)

Article Biochemistry & Molecular Biology

High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector

Yumi Kanegae et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemistry & Molecular Biology

Evidence for extended YFP-EGFR dimers in the absence of ligand on the surface of living cells

Noga Kozer et al.

PHYSICAL BIOLOGY (2011)

Article Mathematical & Computational Biology

Spatio-temporal modeling of signaling protein recruitment to EGFR

Ming-yu Hsieh et al.

BMC SYSTEMS BIOLOGY (2010)

Review Pharmacology & Pharmacy

Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis

Dominik E. Dorer et al.

ADVANCED DRUG DELIVERY REVIEWS (2009)

Review Medicine, Research & Experimental

Understanding and circumventing resistance to anticancer monoclonal antibodies

Lina Reslan et al.

Review Immunology

Colony-stimulating factors in inflammation and autoimmunity

John A. Hamilton

NATURE REVIEWS IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

The genetic design of signaling cascades to record receptor activation

Gilad Barnea et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Medicine, Research & Experimental

ErbB receptors: from oncogenes to targeted cancer therapies

Hongtao Zhang et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Oncology

ERBB receptors and cancer: The complexity of targeted inhibitors

NE Hynes et al.

NATURE REVIEWS CANCER (2005)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

HER2/Neu: mechanisms of dimerization/oligomerization

PJ Brennan et al.

ONCOGENE (2000)

Article Biochemistry & Molecular Biology

Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer

D Fattori et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)