Journal
RUSSIAN CHEMICAL REVIEWS
Volume 88, Issue 6, Pages 644-676Publisher
TURPION LTD
DOI: 10.1070/RCR4864
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Funding
- Russian Science Foundation [17-13-01124]
- Russian Science Foundation [17-13-01124] Funding Source: Russian Science Foundation
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The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review summarizes data on the use of tetrazoles in biomedicine published in the last 10 - 15 years and also views on the nature of their biological effects. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophore are analyzed.
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