Journal
PSYCHIATRY-INTERPERSONAL AND BIOLOGICAL PROCESSES
Volume 82, Issue 3, Pages 272-282Publisher
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/00332747.2019.1600218
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Funding
- Ministry of Science and Technology of China
- National Key R&D Program of China [2016YFC1306803]
- National Natural Science Foundation of China [81671329, 81671332]
- Shanghai Key Laboratory of Psychotic Disorders [13dz2260500]
- Shanghai Shenkang Hospital Development Center, Clinical Research Plan of SHDC [16CR2015A, 16CR3016A]
- Shanghai Key Basic Research Project [16JC1420201]
- Suzhou Municipal Science and Technology Bureau, China [sys2018097]
- Shanghai Mental Health Center Foundation [2016-FX-01, 2017-TSXK-03]
- Program of Shanghai Academic Research Leader [16XD1402400]
- Ministry of Science and Technology of the People's Republic of China [2016YFC1306803]
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Objective: Multiple and overlapping diagnoses of personality disorders (PDs) have been a major obstacle in clinical practice and research. This study aims to investigate the comorbidity of PDs in a sample of a high-risk clinical population. We propose a diagnostic model to address this critical issue. Methods: The sample population included 982 PD patients. The PD diagnoses were concluded based on self-reported and face-to-face interviews. To address the issue of overlapping PD diagnoses, we defined the criteria for clinically distinguishing principal and subordinate PDs, and determined the frequency of each condition. Results: Diagnostic overlap among PDs was quite common across all categories. Of all 982 PD patients, 436 (44.4%) met the criteria for more than one PD. In terms of specific PD diagnoses, the comorbidity rate of each PD was nearly 47.1-74.7%. The principal and subordinate PDs were distinguished accordingly. Avoidant, obsessive-compulsive, and borderline PD remain the most prevalent types of principal PD in this clinical population. Conclusions: The principal/subordinate model may be one strategy of resolving the issue of PD comorbidity in Chinese clinical settings.
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