4.2 Review

Current Advances in Protein Import into Peroxisomes

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Isoform-specific domain organization determines conformation and function of the peroxisomal biogenesis factor PEX26

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The deubiquitination of the PTS1-import receptor Pex5p is required for peroxisomal matrix protein import

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Membrane topologies of PEX13 and PEX14 provide new insights on the mechanism of protein import into peroxisomes

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FEBS JOURNAL (2019)

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Hansenula polymorpha Aat2p is targeted to peroxisomes via a novel Pex20p-dependent pathway

Ann S. Thomas et al.

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Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol

Ana G. Pedrosa et al.

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Insights into the Role of the Peroxisomal Ubiquitination Machinery in Pex13p Degradation in the Yeast Hansenula polymorpha

Xin Chen et al.

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The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading

Brooke M. Gardner et al.

NATURE COMMUNICATIONS (2018)

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The Pex4p-Pex22p complex from Hansenula polymorpha: biophysical analysis, crystallization and X-ray diffraction characterization

Ameena M. Ali et al.

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The peroxisome: an update on mysteries 2.0

Markus Islinger et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2018)

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Receptor recognition by the peroxisomal AAA complex depends on the presence of the ubiquitin moiety and is mediated by Pex1p

Daniel Schwerter et al.

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Pnc1 piggy-back import into peroxisomes relies on Gpd1 homodimerisation

Nadal A. Al Saryi et al.

SCIENTIFIC REPORTS (2017)

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A role for mRNA trafficking and localized translation in peroxisome biogenesis and function?

Gal Haimovich et al.

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Stress exposure results in increased peroxisomal levels of yeast Pnc1 and Gpd1, which are imported via a piggy-backing mechanism

Sanjeev Kumar et al.

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Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery

Anna Chan et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2016)

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Nucleotide-dependent assembly of the peroxisomal receptor export complex

Immanuel Grimm et al.

SCIENTIFIC REPORTS (2016)

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Stefanie Hagen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

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Role of Pex21p for Piggyback Import of Gpd1p and Pnc1p into Peroxisomes of Saccharomyces cerevisiae

Daniel Effelsberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

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ATM functions at the peroxisome to induce pexophagy in response to ROS

Jiangwei Zhang et al.

NATURE CELL BIOLOGY (2015)

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Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy

Neil B. Blok et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

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Molecular snapshots of the Pex1/6 AAA + complex in action

Susanne Ciniawsky et al.

NATURE COMMUNICATIONS (2015)

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Distinct Pores for Peroxisomal Import of PTS1 and PTS2 Proteins

Malayko Montilla-Martinez et al.

CELL REPORTS (2015)

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The peroxisomal protein import machinery displays a preference for monomeric substrates

Marta O. Freitas et al.

OPEN BIOLOGY (2015)

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Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin-proteasome system

Chris Williams et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

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The exportomer: the peroxisomal receptor export machinery

Harald W. Platta et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2013)

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Unique Requirements for Mono- and Polyubiquitination of the Peroxisomal Targeting Signal Co-receptor, Pex20

Xueqian Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

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Redox-regulated Cargo Binding and Release by the Peroxisomal Targeting Signal Receptor, Pex5

Changle Ma et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

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A Cargo-centered Perspective on the PEX5 Receptor-mediated Peroxisomal Protein Import Pathway

Tania Francisco et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

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Arabidopsis RING Peroxins are E3 Ubiquitin Ligases that Interact with Two Homologous Ubiquitin Receptor Proteins

Navneet Kaur et al.

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Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p

Dongqing Pan et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

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Primary Role for Endoplasmic Reticulum-bound Ribosomes in Cellular Translation Identified by Ribosome Profiling

David W. Reid et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

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Identification of Ubiquitin-specific Protease 9X (USP9X) as a Deubiquitinase Acting on Ubiquitin-Peroxin 5 (PEX5) Thioester Conjugate

Claudia P. Grou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Cysteine-dependent Ubiquitination of Pex18p Is Linked to Cargo Translocation across the Peroxisomal Membrane

Astrid Hensel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

PEX5 Protein Binds Monomeric Catalase Blocking Its Tetrarnerization and Releases It upon Binding the N-terminal Domain of PEX14

Marta O. Freitas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Ubp15p, a Ubiquitin Hydrolase Associated with the Peroxisomal Export Machinery

Mykhaylo O. Debelyy et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Be different-The diversity of peroxisomes in the animal kingdom

M. Islinger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)

Article Biochemistry & Molecular Biology

Dynamic Changes in the Subcellular Distribution of Gpd1p in Response to Cell Stress

Sunhee Jung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

The peroxisomal importomer constitutes a large and highly dynamic pore

Michael Meinecke et al.

NATURE CELL BIOLOGY (2010)

Review Cell Biology

Peroxisomal protein import and ERAD: variations on a common theme

Wolfgang Schliebs et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19

Christian Neufeld et al.

EMBO JOURNAL (2009)

Article Biochemistry & Molecular Biology

Pex2 and Pex12 Function as Protein-Ubiquitin Ligases in Peroxisomal Protein Import

Harald W. Platta et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Cell Biology

The Peroxisomal Matrix Import of Pex8p Requires Only PTS Receptors and Pex14p

Changle Ma et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Review Cell Biology

Breaking the chains: structure and function of the deubiquitinases

David Komander et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Localization of mRNAs coding for peroxisomal proteins in the yeast, Saccharomyces cerevisiae

Gadi Zipor et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p

Chris Williams et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Biochemistry & Molecular Biology

Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor

Claudia P. Grou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Review Biochemistry & Molecular Biology

Shuttles and cycles: transport of proteins into the peroxisome matrix

Laura-Anne Brown et al.

MOLECULAR MEMBRANE BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Ubiquitination of mammalian pex5p, the peroxisomal import receptor

Andreia F. Carvalho et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p

Chris Williams et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Cell Biology

Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling

Harald W. Platta et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

A conserved cysteine residue of Pichia pastoris Pex20p is essential for its recycling from the peroxisome to the cytosol

Sebastien Leon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei

Nathalie Galland et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)

Article Biochemistry & Molecular Biology

Recognition of a functional peroxisome type 1 target by the dynamic import receptor Pex5p

Will A. Stanley et al.

MOLECULAR CELL (2006)

Review Biochemistry & Molecular Biology

Peroxisomal disorders: The single peroxisomal enzyme deficiencies

Ronald J. A. Wanders et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)

Review Biochemistry & Molecular Biology

X-linked adrenoleukodystrophy:: Clinical, biochemical and pathogenetic aspects

Johannes Berger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)

Review Biochemistry & Molecular Biology

The importomer - A peroxisomal membrane complex involved in protein translocation into the peroxisome matrix

Naganand Rayapuram et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)

Review Biochemistry & Molecular Biology

Peroxisome targeting signal 1: Is it really a simple tripeptide?

Cecile Brocard et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)

Article Biochemistry & Molecular Biology

Membrane association of the cycling peroxisome import receptor Pex5p

Daniela Kerssen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery

Wolfgang Girzalsky et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export

N Miyata et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Review Plant Sciences

Peroxisome protein import: some answers, more questions

A Baker et al.

CURRENT OPINION IN PLANT BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites

K Niederhoff et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Genetics & Heredity

Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis

S Weller et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2005)

Article Biochemistry & Molecular Biology

The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells

A Kragt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Cell Biology

Peroxisomal matrix protein import: The transient pore model

R Erdmann et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

A new definition for the consensus sequence of the peroxisome targeting signal type 2

OI Petriv et al.

JOURNAL OF MOLECULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Ubiquitination of the peroxisomal import receptor Pex5p

H Platta et al.

BIOCHEMICAL JOURNAL (2004)

Article Biochemistry & Molecular Biology

Physical interactions of the peroxisomal targeting signal 1 receptor Pex5p, studied by fluorescence correlation spectroscopy

DY Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Motif refinement of the peroxisomal targeting signal 1 and evaluation of taxon-specific differences

G Neuberger et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p

JR Pires et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Pex8p:: An intraperioxisomal organizer of the peroxisomal import machinery

B Agne et al.

MOLECULAR CELL (2003)

Article Biochemistry & Molecular Biology

Topography for independent binding of α-helical and PPII-helical ligands to a peroxisomal SH3 domain

A Douangamath et al.

MOLECULAR CELL (2002)

Article Biochemistry & Molecular Biology

Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p

ATJ Klein et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p

G Dodt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Interaction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p

AJ Urquhart et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)