4.8 Article

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression

Xiangming Ji et al.

ONCOGENE (2018)

Article Cell Biology

BAP1 links metabolic regulation of ferroptosis to tumour suppression

Yilei Zhang et al.

NATURE CELL BIOLOGY (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

18F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models

Hua Yang et al.

JOURNAL OF NUCLEAR MEDICINE (2017)

Article Neurosciences

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

Joeri Van Liefferinge et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2016)

Article Biochemistry & Molecular Biology

Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules

Elda Grabocka et al.

Article Cell Biology

NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis

Hui Wang et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Biochemistry & Molecular Biology

Differential Requirements for eIF4E Dose in Normal Development and Cancer

Morgan L. Truitt et al.

Article Multidisciplinary Sciences

Oxidative stress inhibits distant metastasis by human melanoma cells

Elena Piskounova et al.

NATURE (2015)

Article Multidisciplinary Sciences

Ferroptosis as a p53-mediated activity during tumour suppression

Le Jiang et al.

NATURE (2015)

Article Cell Biology

Antioxidants can increase melanoma metastasis in mice

Kristell Le Gal et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Oncology

Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2

Shasha Tao et al.

CANCER RESEARCH (2014)

Article Biochemistry & Molecular Biology

Novel signaling axis for ROS generation during K-Ras-induced cellular transformation

M-T Park et al.

CELL DEATH AND DIFFERENTIATION (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, 18F-5-Fluoro-L- Aminosuberic Acid

Jack M. Webster et al.

JOURNAL OF NUCLEAR MEDICINE (2014)

Article Multidisciplinary Sciences

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son et al.

NATURE (2013)

Review Oncology

A Comprehensive Survey of Ras Mutations in Cancer

Ian A. Prior et al.

CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis

T. L. Ng et al.

CELL DEATH AND DIFFERENTIATION (2012)

Article Cell Biology

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Jessie Yanxiang Guo et al.

GENES & DEVELOPMENT (2011)

Article Multidisciplinary Sciences

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. De Nicola et al.

NATURE (2011)

Review Oncology

RAS oncogenes: weaving a tumorigenic web

Yuliya Pylayeva-Gupta et al.

NATURE REVIEWS CANCER (2011)

Article Biochemistry & Molecular Biology

Phosphorylation of the Transcription Factor Ets-1 by ERK2: Rapid Dissociation of ADP and Phospho-Ets-1

Kari Callaway et al.

BIOCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

Matthias Drosten et al.

EMBO JOURNAL (2010)

Article Multidisciplinary Sciences

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Association of reactive oxygen species levels and radioresistance in cancer stem cells

Maximilian Diehn et al.

NATURE (2009)

Review Biotechnology & Applied Microbiology

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Dunyaporn Trachootham et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Multidisciplinary Sciences

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

AH Bild et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Redox imbalance in cystine/glutamate transporter-deficient mice

H Sato et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

ets-1 is transcriptionally up-regulated by H2O2 via an antioxidant response element

LA Wilson et al.

FASEB JOURNAL (2005)

Article Biochemistry & Molecular Biology

Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation

H Sato et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Review Oncology

Targeting ras signalling pathways in cancer therapy

J Downward

NATURE REVIEWS CANCER (2003)

Article Biochemistry & Molecular Biology

Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

H Sasaki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Biochemistry & Molecular Biology

AP-1 in cell proliferation and survival

E Shaulian et al.

ONCOGENE (2001)