Journal
PHYTOCHEMISTRY LETTERS
Volume 30, Issue -, Pages 69-73Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2018.12.013
Keywords
Chisocheton erythrocarpus Hiern; Meliaceae; Limonoid; Erythrocarpines F-H; Mosquito larvicidal activity
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Funding
- University of Malaya Postgraduate Research Fund [PV040-2011B, PV085/2011A]
- University of Malaya High Impact Research Grant [UM. C/625/1/HIR/MOHE/SC/37]
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A phytochemical investigation on the fruits of Chisocheton erythrocarpus Hiern (Meliaceae) afforded four new limonoids, erythrocarpines F-H (1-3) and 14-deoxy-Delta 1415-xyloccensin K (4), along with seven known compounds (5-11). Erythrocarpines 1-3 are phragmalin-type limonoids with an 1,29-oxymethylene bridge, while 4 is a mexicanolide-type limonoid possessing a rare 3 beta,8 beta-ether linkage. Mosquito larvicidal activity of the limonoids revealed that 4 and 5 were toxic to larvae of Aedes aegypti, Aedes albopictus and Culex Quinquefasciatus.
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