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International Journal of Biological Sciences (2012)
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Gain-of-function Nav1.8 mutations in painful neuropathy
Catharina G. Faber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Prenatal expression of purinergic receptor P2X3 in human dorsal root ganglion
Aihua Pan et al.
PURINERGIC SIGNALLING (2012)
Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
Michael S. Minett et al.
NATURE COMMUNICATIONS (2012)
Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel
Yang Yang et al.
NATURE COMMUNICATIONS (2012)
Nav1.8 channelopathy in mutant mice deficient for myelin protein zero is detrimental to motor axons
Mihai Moldovan et al.
BRAIN (2011)
The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Lishi Li et al.
CELL (2011)
NaV1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas
Anna-Karin Persson et al.
EXPERIMENTAL NEUROLOGY (2011)
Localisation of SCN10A Gene Product Nav1.8 and Novel Pain-Related Ion Channels in Human Heart
Paul Facer et al.
INTERNATIONAL HEART JOURNAL (2011)
Genetic Tracing of Nav1.8-Expressing Vagal Afferents in the Mouse
Laurent Gautron et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2011)
Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits
Juan Zhao et al.
JOURNAL OF NEUROPHYSIOLOGY (2011)
Physiological interactions between Nav1.7 and Nav1.8 sodium channels: a computer simulation study
Jin-Sung Choi et al.
JOURNAL OF NEUROPHYSIOLOGY (2011)
Selective silencing of NaV1.7 decreases excitability and conduction in vagal sensory neurons
Yukiko Muroi et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navβ4 peptide-mediated resurgent sodium currents
Jonathan W. Theile et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Single-cell analysis of sodium channel expression in dorsal root ganglion neurons
Cojen Ho et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons
Hye-Sook Ahn et al.
MOLECULAR PAIN (2011)
Highly localized interactions between sensory neurons and sprouting sympathetic fibers observed in a transgenic tyrosine hydroxylase reporter mouse
Wenrui Xie et al.
MOLECULAR PAIN (2011)
Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
Jan Weiss et al.
NATURE (2011)
The crystal structure of a voltage-gated sodium channel
Jian Payandeh et al.
NATURE (2011)
Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion
Tetsuo Fukuoka et al.
NEUROSCIENCE RESEARCH (2011)
Nav1.9 Channel Contributes to Mechanical and Heat Pain Hypersensitivity Induced by Subacute and Chronic Inflammation
Stephane Lolignier et al.
PLOS ONE (2011)
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
Amanda L. Blasius et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat
Ewan St. John Smith et al.
SCIENCE (2011)
Composition, assembly, and maintenance of excitable membrane domains in myelinated axons
Matthew N. Rasband
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2011)
Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes
Jonathan W. Theile et al.
FRONTIERS IN PHARMACOLOGY (2011)
Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice
Sandra Leo et al.
BEHAVIOURAL BRAIN RESEARCH (2010)
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Nav1.8 sodium channel with efficacy in a model of neuropathic pain
Marc J. C. Scanio et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Subtype-selective Nav1.8 sodium channel blockers: Identification of potent, orally active nicotinamide derivatives
Michael E. Kort et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia
Jin-Sung Choi et al.
BRAIN (2010)
Neuroma Removal for Neuropathic Pain Efficacy and Predictive Value of Lidocaine Infusion
Lone Nikolajsen et al.
CLINICAL JOURNAL OF PAIN (2010)
Corneal confocal microscopy: A novel means to detect nerve fibre damage in idiopathic small fibre neuropathy
Mitra Tavakoli et al.
EXPERIMENTAL NEUROLOGY (2010)
Congenital Insensitivity to Pain: Novel SCN9A Missense and In-frame Deletion Mutations
James J. Cox et al.
HUMAN MUTATION (2010)
Transmembrane Segments Prevent Surface Expression of Sodium Channel Nav1.8 and Promote Calnexin-dependent Channel Degradation
Qian Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents
Brian W. Jarecki et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Nociceptors: the sensors of the pain pathway
Adrienne E. Dubin et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
Anna-Karin Persson et al.
MOLECULAR PAIN (2010)
The Tarantula Toxins ProTx-II and Huwentoxin-IV Differentially Interact with Human Nav1.7 Voltage Sensors to Inhibit Channel Activation and Inactivation
Yucheng Xiao et al.
MOLECULAR PHARMACOLOGY (2010)
Several common variants modulate heart rate, PR interval and QRS duration
Hilma Holm et al.
NATURE GENETICS (2010)
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
Nona Sotoodehnia et al.
NATURE GENETICS (2010)
Genome-wide association study of PR interval
Arne Pfeufer et al.
NATURE GENETICS (2010)
Genetic variation in SCN10A influences cardiac conduction
John C. Chambers et al.
NATURE GENETICS (2010)
DIFFERENTIAL EXPRESSION OF EXON 5 SPLICE VARIANTS OF SODIUM CHANNEL α SUBUNIT mRNAs IN THE DEVELOPING MOUSE BRAIN
E. V. Gazina et al.
NEUROSCIENCE (2010)
Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation
Thomas Bishop et al.
PAIN (2010)
Pain perception is altered by a nucleotide polymorphism in SCN9A
Frank Reimann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A Sodium Channel Gene SCN9A Polymorphism That Increases Nociceptor Excitability
Mark Estacion et al.
ANNALS OF NEUROLOGY (2009)
A Novel Nav1.7 Mutation Producing Carbamazepine-Responsive Erythromelalgia
Tanya Z. Fischer et al.
ANNALS OF NEUROLOGY (2009)
Early- and late-onset inherited erythromelalgia: genotypephenotype correlation
Chongyang Han et al.
BRAIN (2009)
Subtype-selective targeting of voltage-gated sodium channels
Steve England et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Cellular and Molecular Mechanisms of Pain
Allan I. Basbaum et al.
CELL (2009)
Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia
Uwe Ernsberger
CELL AND TISSUE RESEARCH (2009)
Mexiletine-responsive erythromelalgia due to a new Nav1.7 mutation showing use-dependent current fall-off
Jin-Sung Choi et al.
EXPERIMENTAL NEUROLOGY (2009)
Nociceptors: a phylogenetic view
Ewan St. John Smith et al.
JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY (2009)
Activation of neurokinin 3 receptor increases Nav1.9 current in enteric neurons
Carine Copel et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel NaV1.8
Dongmin Shao et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
Coding of pleasant touch by unmyelinated afferents in humans
Line S. Loken et al.
NATURE NEUROSCIENCE (2009)
Functional and pharmacological properties of human and rat NaV1.8 channels
Liam E. Browne et al.
NEUROPHARMACOLOGY (2009)
The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction
Amy M. Ritter et al.
NEUROSCIENCE LETTERS (2009)
Two novel SCN9A mutations causing insensitivity to pain
K. B. Nilsen et al.
PAIN (2009)
Multiple Sodium Channel Isoforms and Mitogen-Activated Protein Kinases Are Present in Painful Human Neuromas
Joel A. Black et al.
ANNALS OF NEUROLOGY (2008)
The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology
Grazia Devigili et al.
BRAIN (2008)
Lack of colonic inflammation-induced acute visceral hypersensitivity to colorectal distension in Nav1.9 knockout mice
V. Martinez et al.
EUROPEAN JOURNAL OF PAIN (2008)
Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed configuration
Yucheng Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The voltage-gated Na+ channel Nav1.8 contains an ER-retention/retrieval signal antagonized by the β3 subunit
Zhen-Ning Zhang et al.
JOURNAL OF CELL SCIENCE (2008)
Tetrodotoxin-resistant voltage-gated sodium channels Nav1.8 and Nav1.9 are expressed in the retina
Brendan J. O'Brien et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2008)
Comparative study of the distribution of the α-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
Tetsuo Fukuoka et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2008)
Inflammatory mediators increase Nav1.9 current and excitability in Nociceptors through a coincident detection mechanism
Francois Maingret et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Biophysical properties of human Nav1.7 splice variants and their regulation by protein kinase A
Aurelien Chatelier et al.
JOURNAL OF NEUROPHYSIOLOGY (2008)
NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders
M. Estacion et al.
JOURNAL OF NEUROSCIENCE (2008)
Phosphorylation of sodium channel Nav1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons
Andy Hudmon et al.
JOURNAL OF NEUROSCIENCE (2008)
Nociceptors Are Interleukin-1β Sensors
Alexander M. Binshtok et al.
JOURNAL OF NEUROSCIENCE (2008)
Voltage-gated sodium channels in nociceptive versus non-nociceptive nodose vagal sensory neurons innervating guinea pig lungs
Kevin Kwong et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9
Johan A. R. Ostman et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable
Sulayman D. Dib-Hajj et al.
MOLECULAR PAIN (2008)
Mutation I136V alters electrophysiological properties of the NaV1.7 channel in a family with onset of erythromelalgia in the second decade
Xiaoyang Cheng et al.
MOLECULAR PAIN (2008)
ProTx-II, a Selective Inhibitor of Nav1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors
William A. Schmalhofer et al.
MOLECULAR PHARMACOLOGY (2008)
Deconstructing voltage sensor function and pharmacology in sodium channels
Frank Bosmans et al.
NATURE (2008)
Phospholipase Cβ3 in mouse and human dorsal root ganglia and spinal cord is a possible target for treatment of neuropathic pain
Tie-Jun Sten Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The cell and molecular basis of mechanical, cold, and inflammatory pain
Bjarke Abrahamsen et al.
SCIENCE (2008)
Physiological resistance of grasshopper mice (Onychomys spp.) to Arizona bark scorpion (Centruroides exilicauda) venom
Ashlee H. Rowe et al.
TOXICON (2008)
Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II
Stanislav Sokolov et al.
MOLECULAR PHARMACOLOGY (2008)
Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
Joost P. H. Drenth et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Portability of paddle motif function and pharmacology in voltage sensors
AbdulRasheed A. Alabi et al.
NATURE (2007)
The neuropathic pain triad: Neurons, immune cells and glia
Joachim Scholz et al.
NATURE NEUROSCIENCE (2007)
Expression of Nav1.9 channels in human dental pulp and trigeminal ganglion
Jason E. Wells et al.
JOURNAL OF ENDODONTICS (2007)
A stop codon mutation in SCN9A causes lack of pain sensation
Sultan Ahmad et al.
HUMAN MOLECULAR GENETICS (2007)
Paroxysmal extreme pain disorder (previously familial rectal pain syndrome)
C. R. Fertleman et al.
NEUROLOGY (2007)
Signaling pathways in sensitization: Toward a nociceptor cell biology
Tim Hucho et al.
NEURON (2007)
The cerebral signature and its modulation for pain perception
Irene Tracey et al.
NEURON (2007)
Sodium channel Nav 1.6 accumulates at the site of infraorbital nerve injury
Michael A. Henry et al.
BMC NEUROSCIENCE (2007)
Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures
Katharina Zimmermann et al.
NATURE (2007)
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
Michael F. Jarvis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Expression and localization of the Nav1.9 sodium channel in enteric neurons and in trigeminal sensory endings: Implication for intestinal reflex function and orofacial pain
Francoise Padilla et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Molecular interactions of the gating modifier toxin ProTx-II with Nav1.5 - Implied existence of a novel toxin binding site coupled to activation
Jaime J. Smith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations
Y. P. Goldberg et al.
CLINICAL GENETICS (2007)
A cation-π interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block
Vincent P. Santarelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
Anthony M. Rush et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Specification and connectivity of neuronal subtypes in the sensory lineage
Frederic Marmigere et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons
Jin-Sung Choi et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Prostaglandin E-2 has no effect on two components of tetrodotoxin-resistant Na+ current in mouse dorsal root ganglion
Taixing Zheng et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2007)
Pharmacological dissection and distribution of NaN/Nav1.9, T-type Ca2+ currents, and mechanically activated cation currents in different populations of DRG neurons
Bertrand Coste et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
Analysis of the variation in use-dependent inactivation of high-threshold tetrodotoxin-resistant sodium currents recorded from rat sensory neurons
P. K. Tripathi et al.
NEUROSCIENCE (2006)
An SCN9A channelopathy causes congenital inability to experience pain
James J. Cox et al.
NATURE (2006)
The voltage-gated sodium channel Nav1.9 is an effector of peripheral inflammatory pain hypersensitivity
Fumimasa Amaya et al.
JOURNAL OF NEUROSCIENCE (2006)
SCN9A mutations in paroxysmal extreme pain disorder:: Allelic variants underlie distinct channel defects and phenotypes
Caroline R. Fertleman et al.
NEURON (2006)
Nav1.7 mutant A863P in erythromelalgia:: Effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons
T. Patrick Harty et al.
JOURNAL OF NEUROSCIENCE (2006)
Na channel inactivation from open and closed states
Clay M. Armstrong
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
μO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits
J. Ekberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
What's in a name - familial rectal pain syndrome becomes paroxysmal extreme pain disorder
C. R. Fertleman et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2006)
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice
Mohammed A. Nassar et al.
MOLECULAR PAIN (2006)
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior
Thomas Foulkes et al.
JOURNAL OF NEUROSCIENCE (2006)
Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice
Kirk Hillsley et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Sodium channel β2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain
Luis F. Lopez-Santiago et al.
JOURNAL OF NEUROSCIENCE (2006)
Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes C-fiber nociceptors with broad action potentials and high Nav1.9 expression
Xin Fang et al.
JOURNAL OF NEUROSCIENCE (2006)
Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states
SK Joshi et al.
PAIN (2006)
Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons
Jin-Sung Choi et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice
Shuying Wang et al.
NEUROBIOLOGY OF AGING (2006)
Developmental changes in electrophysiological properties and synaptic transmission in rat intracardiac ganglion neurons
Katrina Rimmer et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
A single sodium channel mutation produces hyperor hypoexcitability in different types of neurons
Anthony M. Rush et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Voltage sensor conformations in the open and closed states in ROSETTA structural models of K+ channels
Vladimir Yarov-Yarovoy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Differential modulation of sodium channel Nav1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily
Anthony M. Rush et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Sporadic onset of erythermalgia:: A gain-of-function mutation in Nav1.7
CY Han et al.
ANNALS OF NEUROLOGY (2006)
Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-α
XC Jin et al.
JOURNAL OF NEUROSCIENCE (2006)
Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve
Michael A. Henry et al.
PAIN (2006)
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
WA Catterall et al.
PHARMACOLOGICAL REVIEWS (2005)
Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury
BC Hains et al.
BRAIN (2005)
Protein kinase C mediates up-regulation of tetrodotoxin-resistant, persistent Na+ current in rat and mouse sensory neurones
MD Baker
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Relationship between sodium channel Nav1.3 expression and neuropathic pain behavior in rats
JA Lindia et al.
PAIN (2005)
Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons
SD Dib-Hajj et al.
BRAIN (2005)
Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons
AM Rush et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Contribution of the tetrodotoxin-resistant voltage-gated sodium channel Nav1.9 to sensory transmission and nociceptive behavior
BT Priest et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivo
X Fang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons
TR Cummins et al.
FEBS LETTERS (2005)
CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Nav1.8
CJ Liu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin
A Moqrich et al.
SCIENCE (2005)
Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA
JJ Devaux et al.
JOURNAL OF NEUROSCIENCE (2005)
Nociceptor-specific gene deletion using heterozygous Na(v)1.8-Cre recombinase mice
LC Stirling et al.
PAIN (2005)
Gating and modulation of presumptive NaV1.9 channels in enteric and spinal sensory neurons
B Coste et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception
E Einarsdottir et al.
HUMAN MOLECULAR GENETICS (2004)
Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C
K Vijayaragavan et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
Neurokinin NK1 and NK3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain
GJ Sanger
BRITISH JOURNAL OF PHARMACOLOGY (2004)
The extent of cytokine induction in peripheral nerve lesions depends on the mode of injury and NMDA receptor signaling
C Kleinschnitz et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia
Y Yang et al.
JOURNAL OF MEDICAL GENETICS (2004)
Heterologous expression and functional analysis of rat Nav1.8 (SNS) voltage-gated sodium channels in the dorsal root ganglion neuroblastoma cell line ND7-23
VH John et al.
NEUROPHARMACOLOGY (2004)
Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia
N Agarwal et al.
GENESIS (2004)
Differential expression of tetrodotoxin-resistant sodium channels NaV1.8 and NaV1.9 in normal and inflamed rats
RE Coggeshall et al.
NEUROSCIENCE LETTERS (2004)
Aβ-fiber nociceptive primary afferent neurons:: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals
L Djouhri et al.
BRAIN RESEARCH REVIEWS (2004)
Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy
TR Cummins et al.
JOURNAL OF NEUROSCIENCE (2004)
Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis
CY Saab et al.
EXPERIMENTAL BRAIN RESEARCH (2004)
Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain
MA Nassar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface
BS Shah et al.
JOURNAL OF NEUROSCIENCE (2004)
Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2
AB Fotia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat
SS Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats
K Obata et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Expression of alternatively spliced sodium channel α-subunit genes -: Unique splicing patterns are observed in dorsal root ganglia
CK Raymond et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteins
AM Rush et al.
BRAIN RESEARCH (2004)
Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury
XF Zhang et al.
BRAIN RESEARCH (2004)
Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury
BC Hains et al.
JOURNAL OF NEUROSCIENCE (2004)
Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability
MJ Beyak et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Electrophysiological characterization of the tetrodotoxin-resistant Na+ channel, Nav1.9, in mouse dorsal root ganglion neurons
H Maruyama et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Altered expression of ion channel isoforms at the node of Ranvier in P0-deficient myelin mutants
JC Ulzheimer et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
GTPγs increases Nav1.8 current in small-diameter dorsal root ganglia neurons
CY Saab et al.
EXPERIMENTAL BRAIN RESEARCH (2003)
Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons
RI Herzog et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice
C Roza et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
The TTX-resistant sodium channel Nav1.8(SNS/PN3):: expression and correlation with membrane properties in rat nociceptive primary afferent neurons
L Djouhri et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
The principle of gating charge movement in a voltage-dependent K+ channel
YX Jiang et al.
NATURE (2003)
GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones
MD Baker et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
GM Story et al.
CELL (2003)
Pathological C-fibres in patients with a chronic painful condition
K Orstavik et al.
BRAIN (2003)
Indifference rather than insensitivity to pain
CJ Klein et al.
ANNALS OF NEUROLOGY (2003)
Sensory neuron proteins interact with the intracellular domains of sodium channel Nav1.8
M Malik-Hall et al.
MOLECULAR BRAIN RESEARCH (2003)
Sensory and electrophysiological properties of guinea-pig sensory neurones expressing Nav1.7 (PN1) Na+ channel α subunit protein
L Djouhri et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Expression of Nav 1.8 sodium channels perturbs the firing patterns of cerebellar purkinje cells
M Renganathan et al.
BRAIN RESEARCH (2003)
Two tarantula peptides inhibit activation of multiple sodium channels
RE Middleton et al.
BIOCHEMISTRY (2002)
Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena
K Peng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Changes of sodium channel expression in experimental painful diabetic neuropathy
MJ Craner et al.
ANNALS OF NEUROLOGY (2002)
Changes in Na+ channel currents of rat dorsal root ganglion neurons following axotomy and axotomy-induced autotomy
FA Abdulla et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury.
Michael Costigan et al.
BMC NEUROSCIENCE (2002)
Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na+ current and delayed rectifier K+ current in rat sensory neurons
YH Zhang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Nav 1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons
M Renganathan et al.
MOLECULAR BRAIN RESEARCH (2002)
Sodium channel Nav 1.6 is expressed along nonmyelinated axons and it contributes to conduction
JA Black et al.
MOLECULAR BRAIN RESEARCH (2002)
Prostaglandin E2 modulates TTX-R INa in rat colonic sensory neurons
MS Gold et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Role of outer ring carboxylates of the rat skeletal muscle sodium channel pore in proton block
A Khan et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Molecular identities of two tetrodotoxin-resistant sodium channels in corneal axons
JA Black et al.
EXPERIMENTAL EYE RESEARCH (2002)
GDNF and NGF reverse changes in repriming of TTX-sensitive Na+ currents following axotomy of dorsal root ganglion neurons
A Leffler et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Annexin II light chain regulates sensory neuron-specific sodium channel expression
K Okuse et al.
NATURE (2002)
NaN/Nav1.9:: a sodium channel with unique properties
S Dib-Hajj et al.
TRENDS IN NEUROSCIENCES (2002)
The pattern of expression of the voltage-gated sodium channels Nav1.8 and Nav1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models
I Decosterd et al.
PAIN (2002)
A TRP channel that senses cold stimuli and menthol
AM Peier et al.
CELL (2002)
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
DD McKemy et al.
NATURE (2002)
Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons
K Bielefeldt et al.
GASTROENTEROLOGY (2002)
Accumulation of PN1 and PN3 sodium channels in painful human neuroma-evidence from immunocytochemistry
T Kretschmer et al.
ACTA NEUROCHIRURGICA (2002)
Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
J Lai et al.
PAIN (2002)
Differential sensitivity to tetrodotoxin and lack of effect of prostaglandin E-2 on the pharmacology and physiology of propagated action potentials
KJ Farrag et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats
K Bielefeldt et al.
GASTROENTEROLOGY (2002)
Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated
L Tyrrell et al.
JOURNAL OF NEUROSCIENCE (2001)
Direct interaction with contactin targets voltage-gated sodium channel Nav1.9/NaN to the cell membrane.
CJ Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The involvement of the tetrodotoxin-resistant sodium channel Nav1.8 (PN3/SNS) in a rat model of visceral pain
N Yoshimura et al.
JOURNAL OF NEUROSCIENCE (2001)
The changes in expression of three subtypes of TTX sensitive sodium channels in sensory neurons after spinal nerve ligation
CH Kim et al.
MOLECULAR BRAIN RESEARCH (2001)
How the olfactory system makes sense of scents
S Firestein
NATURE (2001)
Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons
RI Herzog et al.
JOURNAL OF NEUROPHYSIOLOGY (2001)
Developmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons
SC Benn et al.
JOURNAL OF NEUROSCIENCE (2001)
Nav1.3 sodium channels: Rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons
TR Cummins et al.
JOURNAL OF NEUROSCIENCE (2001)
Contribution of Nav1.8 sodium channels to action potential electrogenesis in DRG neurons
M Renganathan et al.
JOURNAL OF NEUROPHYSIOLOGY (2001)
Mobilization of the cell adhesion glycoprotein F3/contactin to axonal surfaces is activity dependent
K Pierre et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN)
CJ Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics
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MOLECULAR PHARMACOLOGY (2001)
Hyperalgesia induced by peripheral inflammation is mediated by protein kinase C beta II isozyme in the rat spinal cord
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NEUROSCIENCE (2001)
Sodium currents of large (A beta-type) adult cutaneous afferent dorsal root ganglion neurons display rapid recovery from inactivation before and after axotomy
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NEUROSCIENCE (2001)
Role of protein kinase C epsilon and protein kinase A in a model of paclitaxel-induced painful peripheral neuropathy in the rat
OA Dina et al.
NEUROSCIENCE (2001)
Slow inactivation in voltage-gated sodium channels - Molecular substrates and contributions to channelopathies
YY Vilin et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2001)
Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat
OA Dina et al.
JOURNAL OF NEUROSCIENCE (2000)
β3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain
BS Shah et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis
JA Black et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Potent analgesic effects of GDNF in neuropathic pain states
TJ Boucher et al.
SCIENCE (2000)
α-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons
M Renganathan et al.
JOURNAL OF NEUROPHYSIOLOGY (2000)
Wind-up of spinal cord neurones and pain sensation: much ado about something?
JF Herrero et al.
PROGRESS IN NEUROBIOLOGY (2000)
Sodium channel Nav1.6 is localized at nodes of Ranvier, dendrites, and synapses
JH Caldwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury
CN Liu et al.
PAIN (2000)
Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
K Coward et al.
PAIN (2000)
Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2
F Amaya et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
SNS/PN3 and SNS2/NaN sodium channel-like immunoreactivity in human adult and neonate injured sensory nerves
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FEBS LETTERS (2000)
From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
WA Catterall
NEURON (2000)
Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats
XG Liu et al.
PAIN (2000)
Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors
J Fjell et al.
NEUROREPORT (2000)
Identification of a novel human voltage-gated sodium channel α subunit gene, SCN12A
SY Jeong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
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