Journal
ORGANIC LETTERS
Volume 21, Issue 9, Pages 3407-3411Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01141
Keywords
-
Categories
Funding
- DFG [AN 1064/4-1]
- Boehringer Ingelheim Foundation
- International Max Planck Research School in Chemical and Molecular Biology (Dortmund, Germany)
Ask authors/readers for more resources
A metal-free, regioselective C-H functionalization of heteroaromatic N-oxides has been developed. The method enables the synthesis of various benzylated and alkynylated N-heterocycles in a transition-metal-free manner employing organosilanes as coupling partners. The unanticipated reactivity has been exploited for the synthesis of a number of symmetrical disubstituted acetylenes from ethynyltrimethylsilane via carbon-silicon bond metathesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available