Journal
ORGANIC LETTERS
Volume 21, Issue 9, Pages 3346-3351Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01097
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Funding
- NSF [CHE-1664818]
- NIGMS [R01 GM 113878]
- National Natural Science Foundation of China [21602017]
- Natural Science Foundation of Jiangsu Province [BK20160405]
- University Science Research Project of Jiangsu Province [16KJB150001]
- China Scholarship Council [201708320115]
- Ministerio de Educacion, Cultura y Deporte, Subprograma Estatal de Movilidad
- Fulbright grant visiting scholar program
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Described is a cross-electrophilic, deaminative coupling strategy harnessing Katritzky salts as a new species of electrophile in Ni/photoredox dual catalytic reductive cross-coupling reactions. Distinguishing features of this arylation protocol include its mild reaction conditions, high chemo-selectivity, and adaptability to a variety of complex substrates [i.e., pyridinium salts derived from amines and partners derived from (hetero)aryl bromides].
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