Journal
OPTICS EXPRESS
Volume 27, Issue 11, Pages 16184-16194Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.27.016184
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Funding
- Natural Sciences and Engineering Research Council (NSERC) [RGPIN-2017-03830]
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Double-nanoholes fabricated by colloidal lithography were used for trapping single colloidal particles and single proteins. A gap separation of 60 nm between the cusps of the double-nanohole was achieved in a gold film of 70 nm thickness sputter coated on glass. The cusp separation was reduced steadily down to 10 nm by plasma etching the colloidal particles prior to sputter coating. Scanning electron microscopy was used to locate a particular double-nanohole and it was registered for later microscopy experiments. 30 nm polystyrene particles, the rubisco protein and bovine serum albumin were trapped using a laser focused through the aperture. Compared to other methods that require top-down nanofabrication, this approach is inexpensive and produces high-quality samples. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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