4.6 Article

A deep learning interpretable classifier for diabetic retinopathy disease grading

Journal

NEUROCOMPUTING
Volume 396, Issue -, Pages 465-476

Publisher

ELSEVIER
DOI: 10.1016/j.neucom.2018.07.102

Keywords

Deep learning; Classification; Explanations; Diabetic retinopathy; Model interpretation

Funding

  1. URV [2017PFR-URV-B2-60]
  2. Spanish research projects (Instituto de Salud Carlos III) [PI15/01150, PI12/01535]
  3. Fondos Feder from EU

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In this paper we present a diabetic retinopathy deep learning interpretable classifier. On one hand, it classifies retina images into different levels of severity with good performance. On the other hand, this classifier is able of explaining the classification results by assigning a score for each point in the hidden and input spaces. These scores indicate the pixel contribution to the final classification. To obtain these scores, we propose a new pixel-wise score propagation model that for every neuron, divides the observed output score into two components. With this method, the generated visual maps can be easily interpreted by an ophthalmologist in order to find the underlying statistical regularities that help to the diagnosis of this eye disease. (C) 2019 Elsevier B.V. All rights reserved.

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