Related references
Note: Only part of the references are listed.Mks6 mutations reveal tissue- and cell type-specific roles for the cilia transition zone
Wesley R. Lewis et al.
FASEB JOURNAL (2019)
Single-particle tracking localization microscopy reveals nonaxonemal dynamics of intraflagellar transport proteins at the base of mammalian primary cilia
T. Tony Yang et al.
MOLECULAR BIOLOGY OF THE CELL (2019)
A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia
Tyler Picariello et al.
JOURNAL OF CELL SCIENCE (2019)
When trafficking and signaling mix: How subcellular location shapes G protein-coupled receptor activation of heterotrimeric G proteins
Braden T. Lobingier et al.
TRAFFIC (2019)
Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors
Kazuhisa Nakayama et al.
JOURNAL OF BIOCHEMISTRY (2018)
Structural Basis of Smoothened Activation in Hedgehog Signaling
Pengxiang Huang et al.
CELL (2018)
How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In
Galo Garcia et al.
CURRENT BIOLOGY (2018)
The molecular machines that traffic signaling receptors into and out of cilia
Maxence V. Nachury
CURRENT OPINION IN CELL BIOLOGY (2018)
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog
Ganesh V. Pusapati et al.
DEVELOPMENTAL CELL (2018)
Cell type-specific regulation of ciliary transition zone assembly in vertebrates
Antonia Wiegering et al.
EMBO JOURNAL (2018)
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney
Amandine Viau et al.
EMBO JOURNAL (2018)
Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins
Stine Kjaer Morthorst et al.
FEBS JOURNAL (2018)
SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium
Rachayata Dharmat et al.
JOURNAL OF CELL BIOLOGY (2018)
Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis
Teruki Funabashi et al.
JOURNAL OF CELL BIOLOGY (2018)
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
Fan Ye et al.
JOURNAL OF CELL BIOLOGY (2018)
The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane
Ekaterina Revenkova et al.
JOURNAL OF CELL SCIENCE (2018)
Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease
Qian Wang et al.
KIDNEY INTERNATIONAL (2018)
The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length
Emily L. Hunter et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
Intraflagellar transport is deeply integrated in hedgehog signaling
Thibaut Eguether et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
Differential regulation of transition zone and centriole proteins contributes to ciliary base diversity
Swadhin Chandra Jana et al.
NATURE CELL BIOLOGY (2018)
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow et al.
NATURE GENETICS (2018)
Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity
Jacqueline E. Siljee et al.
NATURE GENETICS (2018)
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Niels Grarup et al.
NATURE GENETICS (2018)
Loss-of-function mutations in ADCY3 cause monogenic severe obesity
Sadia Saeed et al.
NATURE GENETICS (2018)
Shedding light on the cell biology of extracellular vesicles
Guillaume van Niel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
The Bardet-Biedl syndrome protein complex is an adapter expanding the cargo range of intraflagellar transport trains for ciliary export
Peiwei Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Structural basis for the recognition of Sonic Hedgehog by human Patchedl
Xin Gong et al.
SCIENCE (2018)
Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components
T. Tony Yang et al.
NATURE COMMUNICATIONS (2018)
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium
Xiaowen Liu et al.
ELIFE (2018)
Structures of human Patched and its complex with native palmitoylated sonic hedgehog
Xiaofeng Qi et al.
NATURE (2018)
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex
Xiaofeng Qi et al.
SCIENCE (2018)
Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched
Yunxiao Zhang et al.
CELL (2018)
Intraflagellar Transport Complex A Genes Differentially Regulate Cilium Formation and Transition Zone Gating
Noemie Scheidel et al.
CURRENT BIOLOGY (2018)
Role for intraflagellar transport in building a functional transition zone
Victor L. Jensen et al.
EMBO REPORTS (2018)
Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery
Jenna L. Wingfield et al.
MICROTUBULES AND CENTROSOMES (2018)
Cilia-Associated Oxysterols Activate Smoothened
David R. Raleigh et al.
MOLECULAR CELL (2018)
The cryo-EM structure of intraflagellar transport trains reveals how dynein is inactivated to ensure unidirectional anterograde movement in cilia
Mareike A. Jordan et al.
NATURE CELL BIOLOGY (2018)
Interplay between Ciliary Ultrastructure and IFT-Train Dynamics Revealed by Single-Molecule Super-resolution Imaging
Felix Oswald et al.
CELL REPORTS (2018)
Single-Molecule Turnarounds of Intraflagellar Transport at the C-elegans Ciliary Tip
Jona Mijalkovic et al.
CELL REPORTS (2018)
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function
Laura Vuolo et al.
ELIFE (2018)
Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E
Shohei Nozaki et al.
JOURNAL OF CELL SCIENCE (2017)
Progress in ciliary ion channel physiology
Juan Lorenzo Pablo et al.
JOURNAL OF GENERAL PHYSIOLOGY (2017)
Primary Cilia and Mammalian Hedgehog Signaling
Fiona Bangs et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Ciliopathies
Daniela A. Braun et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition
Francesc R. Garcia-Gonzalo et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF)
Anna A. Ivanova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation
Kasturi Roy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46
Michael Taschner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release
Raquel Y. Salinas et al.
JOURNAL OF CELL BIOLOGY (2017)
Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins
Hemant B. Badgandi et al.
JOURNAL OF CELL BIOLOGY (2017)
BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia
William J. Monis et al.
JOURNAL OF CELL BIOLOGY (2017)
Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans
Daniel Serwas et al.
JOURNAL OF CELL BIOLOGY (2017)
The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16
Yuqing Hou et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly
Yuya Nishijima et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors
Tomoaki Hirano et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
The Ciliary Transition Zone: Finding the Pieces and Assembling the Gate
Joao Goncalves et al.
MOLECULES AND CELLS (2017)
Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome
Xiaoyu Shi et al.
NATURE CELL BIOLOGY (2017)
Genes and molecular pathways underpinning ciliopathies
Jeremy F. Reiter et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Sperm Sensory Signaling
Dagmar Wachten et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease
Ming Ma et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling
Kenneth B. Schou et al.
NATURE COMMUNICATIONS (2017)
Dynamics of the IFT machinery at the ciliary tip
Alexander Chien et al.
ELIFE (2017)
A recombinant BBSome core complex and how it interacts with ciliary cargo
Bjoern Udo Klink et al.
ELIFE (2017)
Centriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans
Inna V. Nechipurenko et al.
ELIFE (2017)
IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium
Jenna L. Wingfield et al.
ELIFE (2017)
Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons
Wenjing Li et al.
EMBO JOURNAL (2017)
Gates for soluble and membrane proteins, and two trafficking systems (IFT and LIFT), establish a dynamic ciliary signaling compartment
Victor L. Jensen et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Protein Interaction Analysis Provides a Map of the Spatial and Temporal Organization of the Ciliary Gating Zone
Daisuke Takao et al.
CURRENT BIOLOGY (2017)
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base
Tomoharu Kanie et al.
DEVELOPMENTAL CELL (2017)
The native TRPP2-dependent channel of murine renal primary cilia
Steven J. Kleene et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling
Andrew R. Nager et al.
CELL (2017)
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
Siew Cheng Phua et al.
CELL (2017)
TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome
Nils J. Lambacher et al.
NATURE CELL BIOLOGY (2016)
Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei
Gerasimos Langousis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Shuttling and sorting lipid-modified cargo into the cilia
Louise A. Stephen et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling
Pengxiang Huang et al.
CELL (2016)
Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia
Anthony J. Szempruch et al.
CELL (2016)
Comparative Analysis of Ciliary Membranes and Ectosomes
Huan Long et al.
CURRENT BIOLOGY (2016)
The primary cilium as a cellular receiver: organizing ciliary GPCR signaling
Keren I. Hilgendorf et al.
CURRENT OPINION IN CELL BIOLOGY (2016)
Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium
Kasturi Pal et al.
JOURNAL OF CELL BIOLOGY (2016)
Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin
Tomohiro Kubo et al.
JOURNAL OF CELL SCIENCE (2016)
Single-particle imaging reveals intraflagellar transport-independent transport and accumulation of EB1 in Chlamydomonas flagella
J. Aaron Harris et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
Primary cilia are not calcium-responsive mechanosensors
M. Delling et al.
NATURE (2016)
Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics
Bryn S. Moore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Microtubule doublets are double-track railways for intraflagellar transport trains
Ludek Stepanek et al.
SCIENCE (2016)
Endocytic Control of Cellular Signaling at the Primary Cilium
Lotte B. Pedersen et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
H. Broder Schmidt et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate
Qing Wei et al.
NATURE COMMUNICATIONS (2016)
PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity
Eyad Kalawy Fansa et al.
NATURE COMMUNICATIONS (2016)
GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119
Qing Zhang et al.
SCIENTIFIC REPORTS (2016)
Role for the IFT-A Complex in Selective Transport to the Primary Cilium
Wenxiang Fu et al.
CELL REPORTS (2016)
Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling
Giovanni Luchetti et al.
eLife (2016)
A novel biosensor to study cAMP dynamics in cilia and flagella
Shatanik Mukherjee et al.
ELIFE (2016)
Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation
Nicolas Chiaruttini et al.
CELL (2015)
Proteomic Analysis of Isolated Ciliary Transition Zones Reveals the Presence of ESCRT Proteins
Dennis R. Diener et al.
CURRENT BIOLOGY (2015)
Assembly of IFT Trains at the Ciliary Base Depends on IFT74
Jason M. Brown et al.
CURRENT BIOLOGY (2015)
Proteomics of Primary Cilia by Proximity Labeling
David U. Mick et al.
DEVELOPMENTAL CELL (2015)
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
Marcelo Chavez et al.
DEVELOPMENTAL CELL (2015)
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Francesc R. Garcia-Gonzalo et al.
DEVELOPMENTAL CELL (2015)
Formation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP2 ciliary abundance
Victor Jensen et al.
EMBO JOURNAL (2015)
Ins and outs of GPCR signaling in primary cilia
Kenneth Bodtker Schou et al.
EMBO REPORTS (2015)
TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone
Elle C. Roberson et al.
JOURNAL OF CELL BIOLOGY (2015)
Barriers to the free diffusion of proteins and lipids in the plasma membrane
William S. Trimble et al.
JOURNAL OF CELL BIOLOGY (2015)
Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism
Julie M. Craft et al.
JOURNAL OF CELL BIOLOGY (2015)
Ciliary adenylyl cyclases control the Hedgehog pathway
Laura Vuolo et al.
JOURNAL OF CELL SCIENCE (2015)
Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1
Ljiljana Milenkovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome
Poppy Datta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
IFT-Cargo Interactions and Protein Transport in Cilia
Karl F. Lechtreck
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Ciliary ectosomes: transmissions from the cell's antenna
Christopher R. Wood et al.
TRENDS IN CELL BIOLOGY (2015)
Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells
Laura Fiorini et al.
ONCOTARGET (2015)
Ciliary Phosphoinositide Regulates Ciliary Protein Trafficking in Drosophila
Jina Park et al.
CELL REPORTS (2015)
Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling
Laura E. Yee et al.
PLOS GENETICS (2015)
Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding
Muqing Cao et al.
ELIFE (2015)
A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins
Katja Gotthardt et al.
ELIFE (2015)
Flagellar membranes are rich in raft-forming phospholipids
Mauro Serricchio et al.
BIOLOGY OPEN (2015)
C-elegans Ciliated Sensory Neurons Release Extracellular Vesicles that Function in Animal Communication
Juan Wang et al.
CURRENT BIOLOGY (2014)
Cytokinetic Abscission: Molecular Mechanisms and Temporal Control
Beata Mierzwa et al.
DEVELOPMENTAL CELL (2014)
The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from Cilia through the GTPase ARL6/BBS3
Gerald M. Liew et al.
DEVELOPMENTAL CELL (2014)
IFT27 Links the BBSome to IFT for Maintenance of the Ciliary Signaling Compartment
Thibaut Eguether et al.
DEVELOPMENTAL CELL (2014)
Diverse Cell Type-Specific Mechanisms Localize G Protein-Coupled Receptors to Caenorhabditis elegans Sensory Cilia
Andrea G. Brear et al.
GENETICS (2014)
NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone
Junya Awata et al.
JOURNAL OF CELL SCIENCE (2014)
Ciliopathy proteins establish a bipartite signaling compartment in a C-elegans thermosensory neuron
Phuong Anh T. Nguyen et al.
JOURNAL OF CELL SCIENCE (2014)
Adenylyl Cyclase 6 Deficiency Ameliorates Polycystic Kidney Disease
Sara Rees et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment
Mu He et al.
NATURE CELL BIOLOGY (2014)
Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis
Raman M. Das et al.
SCIENCE (2014)
The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling
Yulu C. Liu et al.
SCIENCE SIGNALING (2014)
Regulated Membrane Protein Entry into Flagella Is Facilitated by Cytoplasmic Microtubules and Does Not Require IFT
Olivier Belzile et al.
CURRENT BIOLOGY (2013)
The Cilium Secretes Bioactive Ectosomes
Christopher R. Wood et al.
CURRENT BIOLOGY (2013)
IGF-1 Activates a Cilium-Localized Noncanonical Gβγ Signaling Pathway that Regulates Cell-Cycle Progression
Celine Yeh et al.
DEVELOPMENTAL CELL (2013)
Centriole distal appendages promote membrane docking, leading to cilia initiation
Barbara E. Tanos et al.
GENES & DEVELOPMENT (2013)
Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase
Karl F. Lechtreck et al.
JOURNAL OF CELL BIOLOGY (2013)
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier
David K. Breslow et al.
JOURNAL OF CELL BIOLOGY (2013)
Direct recording and molecular identification of the calcium channel of primary cilia
Paul G. DeCaen et al.
NATURE (2013)
Primary cilia are specialized calcium signalling organelles
Markus Delling et al.
NATURE (2013)
Chemically inducible diffusion trap at cilia reveals molecular sieve-like barrier
Yu-Chun Lin et al.
NATURE CHEMICAL BIOLOGY (2013)
Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
Ming Ma et al.
NATURE GENETICS (2013)
A Role for the Membrane in Regulating Chlamydomonas Flagellar Length
William Dentler
PLOS ONE (2013)
Evolution of modular intraflagellar transport from a coatomer-like progenitor
Teunis J. P. van Dam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81
Sagar Bhogaraju et al.
SCIENCE (2013)
Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia
Alexander V. Loktev et al.
CELL REPORTS (2013)
TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium
Christian Alexandro Clement et al.
CELL REPORTS (2013)
dTULP, the Drosophila melanogaster Homolog of Tubby, Regulates Transient Receptor Potential Channel Localization in Cilia
Jina Park et al.
PLOS GENETICS (2013)
Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain
Sebiha Cevik et al.
PLOS GENETICS (2013)
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors
Fan Ye et al.
ELIFE (2013)
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119
Shehab A. Ismail et al.
EMBO JOURNAL (2012)
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
Karel F. Liem et al.
JOURNAL OF CELL BIOLOGY (2012)
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
Ben Chih et al.
NATURE CELL BIOLOGY (2012)
A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia
Hooi Lynn Kee et al.
NATURE CELL BIOLOGY (2012)
Steric volume exclusion sets soluble protein concentrations in photoreceptor sensory cilia
Mehdi Najafi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
Melissa C. Humbert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Ultrastructure of cilia and flagella - back to the future!
Cathy Fisch et al.
BIOLOGY OF THE CELL (2011)
A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development
Ellen J. Ezratty et al.
CELL (2011)
Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways
Liyun Sang et al.
CELL (2011)
An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium
Kevin J. Wright et al.
GENES & DEVELOPMENT (2011)
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
Corey L. Williams et al.
JOURNAL OF CELL BIOLOGY (2011)
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo
Shehab A. Ismail et al.
NATURE CHEMICAL BIOLOGY (2011)
Complex interactions between genes controlling trafficking in primary cilia
Polloneal Jymmiel R. Ocbina et al.
NATURE GENETICS (2011)
UNC119 is required for G protein trafficking in sensory neurons
Houbin Zhang et al.
NATURE NEUROSCIENCE (2011)
The Retrograde IFT Machinery of C. elegans Cilia: Two IFT Dynein Complexes?
Limin Hao et al.
PLOS ONE (2011)
The Hedgehog Receptor Patched Is Involved in Cholesterol Transport
Michel Bidet et al.
PLOS ONE (2011)
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes
Qihong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
Christopher S. Von Bartheld et al.
PROGRESS IN NEUROBIOLOGY (2011)
Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?
Maxence V. Nachury et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)
The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia
Hua Jin et al.
CELL (2010)
Actin Dynamics Drive Membrane Reorganization and Scission in Clathrin-Independent Endocytosis
Winfried Roemer et al.
CELL (2010)
Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells
Ronald Y. Kwon et al.
FASEB JOURNAL (2010)
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
Saikat Mukhopadhyay et al.
GENES & DEVELOPMENT (2010)
The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development
Toby Hurd et al.
HUMAN MOLECULAR GENETICS (2010)
The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium
R. Jane Evans et al.
HUMAN MOLECULAR GENETICS (2010)
The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis
Yujie Li et al.
JOURNAL OF CELL BIOLOGY (2010)
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
Sebiha Cevik et al.
JOURNAL OF CELL BIOLOGY (2010)
CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content
Branch Craige et al.
JOURNAL OF CELL BIOLOGY (2010)
The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence
John A. Follit et al.
JOURNAL OF CELL BIOLOGY (2010)
Sensory reception is an attribute of both primary cilia and motile cilia
Robert A. Bloodgood
JOURNAL OF CELL SCIENCE (2010)
Molecular mechanisms of protein and lipid targeting to ciliary membranes
Brian T. Emmer et al.
JOURNAL OF CELL SCIENCE (2010)
Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium
Peter D. Calvert et al.
JOURNAL OF GENERAL PHYSIOLOGY (2010)
Lipidomic Analysis of Porcine Olfactory Epithelial Membranes and Cilia
Simona Lobasso et al.
LIPIDS (2010)
Signaling by olfactory receptor neurons near threshold
Vikas Bhandawat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The major α-tubulin K40 acetyltransferase αTAT1 promotes rapid ciliogenesis and efficient mechanosensation
Toshinobu Shida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution
Qicong Hu et al.
SCIENCE (2010)
cAMP and cGMP signaling: sensory systems with prokaryotic roots adopted by eukaryotic cilia
Jacque-Lynne F. Johnson et al.
TRENDS IN CELL BIOLOGY (2010)
The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development
Setsu Endoh-Yamagami et al.
CURRENT BIOLOGY (2009)
Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6
Marion Delous et al.
HUMAN MOLECULAR GENETICS (2009)
The ubiquitin conjugation system is involved in the disassembly of cilia and flagella
Kaiyao Huang et al.
JOURNAL OF CELL BIOLOGY (2009)
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella
Karl-Ferdinand Lechtreck et al.
JOURNAL OF CELL BIOLOGY (2009)
Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane
Brian T. Emmer et al.
JOURNAL OF CELL SCIENCE (2009)
Flagellar membrane localization via association with lipid rafts
Kevin M. Tyler et al.
JOURNAL OF CELL SCIENCE (2009)
Dynein-2 Affects the Regulation of Ciliary Length but Is Not Required for Ciliogenesis in Tetrahymena thermophila
Vidyalakshmi Rajagopalan et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Membrane scission by the ESCRT-III complex
Thomas Wollert et al.
NATURE (2009)
Physiological Roles for G Protein-Regulated Adenylyl Cyclase Isoforms: Insights from Knockout and Overexpression Studies
Rachna Sadana et al.
NEUROSIGNALS (2009)
The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling
Helen Oi-Lam Cheung et al.
SCIENCE SIGNALING (2009)
Intraflagellar Transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts
Polloneal Jymmiel R. Ocbina et al.
DEVELOPMENTAL DYNAMICS (2008)
The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors
Sheila A. Baker et al.
JOURNAL OF CELL BIOLOGY (2008)
The keratin-binding protein Albatross regulates polarization of epithelial cells
Masahiko Sugimoto et al.
JOURNAL OF CELL BIOLOGY (2008)
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella
Kaiyao Huang et al.
JOURNAL OF CELL BIOLOGY (2007)
Disruption of the basal body comprises proteasomal function and perturbs intracellular Wnt response
Jantje M. Gerdes et al.
NATURE GENETICS (2007)
An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport
Angela Stephan et al.
TRAFFIC (2007)
Patched1 regulates Hedgehog signaling at the primary cilium
Rajat Rohatgi et al.
SCIENCE (2007)
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
Maxence V. Nachury et al.
CELL (2007)
Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans
Jan Burghoorn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Actin polymerization serves as a membrane domain switch in model lipid bilayers
Allen P. Liu et al.
BIOPHYSICAL JOURNAL (2006)
General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia
Young-Kyung Bae et al.
DEVELOPMENT (2006)
A β-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors
S Marion et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
SR May et al.
DEVELOPMENTAL BIOLOGY (2005)
PDGFRαα signaling is regulated through the primary cilium in fibroblasts
L Schneider et al.
CURRENT BIOLOGY (2005)
Vertebrate Smoothened functions at the primary cilium
KC Corbit et al.
NATURE (2005)
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
AJ Ross et al.
NATURE GENETICS (2005)
Gli2 and Gli3 localize to cilia and require the intra-flagellar transport protein polaris for processing and function
CJ Haycraft et al.
PLOS GENETICS (2005)
Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway
JS Goodwin et al.
JOURNAL OF CELL BIOLOGY (2005)
Functional genomics of the cilium, a sensory organelle
OE Blacque et al.
CURRENT BIOLOGY (2005)
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
O Rocks et al.
SCIENCE (2005)
LmxMPK9, a mitogen-activated protein kinase homologue affects flagellar length in Leishmania mexicana
F Bengs et al.
MOLECULAR MICROBIOLOGY (2005)
Fission of a multiphase membrane tube
JM Allain et al.
PHYSICAL REVIEW LETTERS (2004)
The microtubule plus end-tracking protein EB1 is localized to the flagellar tip and basal bodies in Chlamydomonas reinhardtii
LB Pedersen et al.
CURRENT BIOLOGY (2003)
Hedgehog signalling in the mouse requires intraflagellar transport proteins
DW Huangfu et al.
NATURE (2003)
A novel MAP kinase regulates flagellar length in Chlamydomonas
SA Berman et al.
CURRENT BIOLOGY (2003)
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
SM Nauli et al.
NATURE GENETICS (2003)
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
BK Yoder et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
GJ Pazour et al.
CURRENT BIOLOGY (2002)
Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles
JA Deane et al.
CURRENT BIOLOGY (2001)
Polarized dendritic transport and the AP-1 μ1 clathrin adaptor UNC-101 localize odorant receptors to olfactory cilia
ND Dwyer et al.
NEURON (2001)
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene Tg737, are required for assembly of cilia and flagella
GJ Pazour et al.
JOURNAL OF CELL BIOLOGY (2000)
Share Paper
