Related references
Note: Only part of the references are listed.Fine-mapping of 98 obesity loci in Mexican children
Hsin Yen Liu et al.
INTERNATIONAL JOURNAL OF OBESITY (2019)
Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways
Philip R. Jansen et al.
NATURE GENETICS (2019)
Integrating behavioural health tracking in human genetics research
Nelson B. Freimer et al.
NATURE REVIEWS GENETICS (2019)
Established and emerging strategies to crack the genetic code of obesity
V. Tam et al.
OBESITY REVIEWS (2019)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Valerie Turcot et al.
NATURE GENETICS (2018)
Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry
Sandra Sanchez-Roige et al.
NATURE NEUROSCIENCE (2018)
Ethnic and population differences in the genetic predisposition to human obesity
C. Stryjecki et al.
OBESITY REVIEWS (2018)
The Post-GWAS Era: From Association to Function
Michael D. Gallagher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model
Naomi R. Wray et al.
CELL (2018)
The case of GWAS of obesity: does body weight control play by the rules?
Manfred J. Mueller et al.
INTERNATIONAL JOURNAL OF OBESITY (2018)
GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity
J. R. Speakman et al.
INTERNATIONAL JOURNAL OF OBESITY (2018)
Genotype Imputation from Large Reference Panels
Sayantan Das et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 19 (2018)
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways
Mats Nagel et al.
NATURE GENETICS (2018)
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Niels Grarup et al.
NATURE GENETICS (2018)
Loss-of-function mutations in ADCY3 cause monogenic severe obesity
Sadia Saeed et al.
NATURE GENETICS (2018)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Anubha Mahajan et al.
NATURE GENETICS (2018)
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
James J. Lee et al.
NATURE GENETICS (2018)
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency
Karine Clement et al.
NATURE MEDICINE (2018)
The personal and clinical utility of polygenic risk scores
Ali Torkamani et al.
NATURE REVIEWS GENETICS (2018)
From genome-wide associations to candidate causal variants by statistical fine-mapping
Daniel J. Schaid et al.
NATURE REVIEWS GENETICS (2018)
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Matthias Thurner et al.
ELIFE (2018)
Meta-analysis of genome-wide association studies for height and body mass index in ∼700 000 individuals of European ancestry
Loic Yengo et al.
HUMAN MOLECULAR GENETICS (2018)
Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits
Yan Zhang et al.
NATURE GENETICS (2018)
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
Amit V. Khera et al.
NATURE GENETICS (2018)
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Angli Xue et al.
NATURE COMMUNICATIONS (2018)
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors
Luca A. Lotta et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)
Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease
Sebastien Theriault et al.
CIRCULATION-GENOMIC AND PRECISION MEDICINE (2018)
A Decade of GWAS Results in Lung Cancer
Yohan Bosse et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2018)
Resetting the bar: Statistical significance in whole-genome sequencing-based association studies of global populations
Sara L. Pulit et al.
GENETIC EPIDEMIOLOGY (2017)
Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
Jacqueline M. Lane et al.
NATURE GENETICS (2017)
Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine
Kathleen M. Giacomini et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Dissecting the genetics of complex traits using summary association statistics
Bogdan Pasaniuc et al.
NATURE REVIEWS GENETICS (2017)
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
Jacqueline MacArthur et al.
NUCLEIC ACIDS RESEARCH (2017)
Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel
Mario Mitt et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2017)
Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives
Monica D. Ramstetter et al.
GENETICS (2017)
Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution
Reedik Magi et al.
HUMAN MOLECULAR GENETICS (2017)
Rare and low-frequency coding variants alter human adult height
Eirini Marouli et al.
NATURE (2017)
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
Zhiqiang Li et al.
NATURE GENETICS (2017)
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Roger L. Milne et al.
NATURE GENETICS (2017)
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Wei Zhao et al.
NATURE GENETICS (2017)
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de lange et al.
NATURE GENETICS (2017)
Reevaluation of SNP heritability in complex human traits
Doug Speed et al.
NATURE GENETICS (2017)
Detection and quantification of inbreeding depression for complex traits from SNP data
Loic Yengo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
Lorraine Southam et al.
NATURE COMMUNICATIONS (2017)
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
Audrey E. Hendricks et al.
SCIENTIFIC REPORTS (2017)
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
Maggie C. Y. Ng et al.
PLOS GENETICS (2017)
Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives
Monica D. Ramstetter et al.
GENETICS (2017)
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
Tinh-Hai Collet et al.
MOLECULAR METABOLISM (2017)
Data Descriptor: Whole genome characterization of sequence diversity of 15,220 Icelanders
Hakon Jonsson et al.
SCIENTIFIC DATA (2017)
Assessing the Heritability of Complex Traits in Humans: Methodological Challenges and Opportunities
Alexandra J. Mayhew et al.
CURRENT GENOMICS (2017)
Genome-wide association studies of cancer: current insights and future perspectives
Amit Sud et al.
NATURE REVIEWS CANCER (2017)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Robert A. Scott et al.
DIABETES (2017)
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Laramie Duncan et al.
AMERICAN JOURNAL OF PSYCHIATRY (2017)
10 Years of GWAS Discovery: Biology, Function, and Translation
Peter M. Visscher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Alisa Manning et al.
DIABETES (2017)
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
Victor Rusu et al.
CELL (2017)
An Expanded View of Complex Traits: From Polygenic to Omnigenic
Evan A. Boyle et al.
CELL (2017)
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Ioanna Tachmazidou et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting
Pradeep Natarajan et al.
CIRCULATION (2017)
Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity
Ruixin Liu et al.
DIABETES (2017)
Predicting Polygenic Obesity Using Genetic Information
Ruth J. F. Loos et al.
CELL METABOLISM (2017)
Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases
Chuanhua Xing et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2016)
Prenatal SNP array testing in 1000 fetuses with ultrasound anomalies: causative, unexpected and susceptibility CNVs
Malgorzata I. Srebniak et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2016)
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
Paul S. de Vries et al.
HUMAN MOLECULAR GENETICS (2016)
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Janine F. Felix et al.
HUMAN MOLECULAR GENETICS (2016)
HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease
Lucas D. Ward et al.
NUCLEIC ACIDS RESEARCH (2016)
Genome-Wide Association Study Suggested the PTPRD Polymorphisms Were Associated With Weight Gain Effects of Atypical Antipsychotic Medications
Hao Yu et al.
SCHIZOPHRENIA BULLETIN (2016)
Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data
Huwenbo Shi et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals
John D. Eicher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
The importance of gene-environment interactions in human obesity
Hudson Reddon et al.
CLINICAL SCIENCE (2016)
Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity
Marie Pigeyre et al.
CLINICAL SCIENCE (2016)
Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study
Amelie Bonnefond et al.
DIABETES CARE (2016)
Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively
Andrew R. Wood et al.
DIABETOLOGIA (2016)
The second decade of 3C technologies: detailed insights into nuclear organization
Annette Denker et al.
GENES & DEVELOPMENT (2016)
Testing the role of predicted gene knockouts in human anthropometric trait variation
Samuel Lessard et al.
HUMAN MOLECULAR GENETICS (2016)
Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer
Simon N. Stacey et al.
HUMAN MOLECULAR GENETICS (2016)
The genetic history of Ice Age Europe
Qiaomei Fu et al.
NATURE (2016)
The genetic architecture of type 2 diabetes
Christian Fuchsberger et al.
NATURE (2016)
Schizophrenia risk from complex variation of complement component 4
Aswin Sekar et al.
NATURE (2016)
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
NATURE (2016)
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
Nathan Pankratz et al.
NATURE GENETICS (2016)
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Praveen Surendran et al.
NATURE GENETICS (2016)
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
Craig L. Hyde et al.
NATURE GENETICS (2016)
A thrifty variant in CREBRF strongly influences body mass index in Samoans
Ryan L. Minster et al.
NATURE GENETICS (2016)
Detection and interpretation of shared genetic influences on 42 human traits
Joseph K. Pickrell et al.
NATURE GENETICS (2016)
A reference panel of 64,976 haplotypes for genotype imputation
Shane McCarthy et al.
NATURE GENETICS (2016)
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Zhihong Zhu et al.
NATURE GENETICS (2016)
Integrative approaches for large-scale transcriptome-wide association studies
Alexander Gusev et al.
NATURE GENETICS (2016)
Unravelling the human genome-phenome relationship using phenome-wide association studies
William S. Bush et al.
NATURE REVIEWS GENETICS (2016)
Type 2 diabetes: genetic data sharing to advance complex disease research
Jason Flannick et al.
NATURE REVIEWS GENETICS (2016)
Developing and evaluating polygenic risk prediction models for stratified disease prevention
Nilanjan Chatterjee et al.
NATURE REVIEWS GENETICS (2016)
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
Peter Kuehnen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Yingchang Lu et al.
NATURE COMMUNICATIONS (2016)
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Janina S. Ried et al.
NATURE COMMUNICATIONS (2016)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Tuomas O. Kilpelainen et al.
NATURE COMMUNICATIONS (2016)
Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States
Paige Maas et al.
JAMA ONCOLOGY (2016)
The real cost of sequencing: scaling computation to keep pace with data generation
Paul Muir et al.
GENOME BIOLOGY (2016)
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Bjarni J. Vilhjalmsson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies
Gleb Kichaev et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?
Amelie Bonnefond et al.
CELL METABOLISM (2015)
Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease
Stephanie Ross et al.
EUROPEAN HEART JOURNAL (2015)
Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study
Carolina Medina-Gomez et al.
EUROPEAN JOURNAL OF EPIDEMIOLOGY (2015)
Contrasting genetic architectures in different mouse reference populations used for studying complex traits
David A. Buchner et al.
GENOME RESEARCH (2015)
Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals
Kevin T. Nead et al.
HUMAN MOLECULAR GENETICS (2015)
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity
Sara Hagg et al.
HUMAN MOLECULAR GENETICS (2015)
A genome-wide association study of body mass index across early life and childhood
Nicole M. Warrington et al.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2015)
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials
Jessica L. Mega et al.
LANCET (2015)
Prostate cancer screening in men aged 50-69 years (STHLM3): a prospective population-based diagnostic study
Henrik Gronberg et al.
LANCET ONCOLOGY (2015)
New genetic loci link adipose and insulin biology to body fat distribution
Dmitry Shungin et al.
NATURE (2015)
Integrative analysis of 111 reference human epigenomes
Anshul Kundaje et al.
NATURE (2015)
A global reference for human genetic variation
David M. Altshuler et al.
NATURE (2015)
The UK10K project identifies rare variants in health and disease
Klaudia Walter et al.
NATURE (2015)
Genetic studies of body mass index yield new insights for obesity biology
Adam E. Locke et al.
NATURE (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
Suna Onengut-Gumuscu et al.
NATURE GENETICS (2015)
The support of human genetic evidence for approved drug indications
Matthew R. Nelson et al.
NATURE GENETICS (2015)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Majid Nikpay et al.
NATURE GENETICS (2015)
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Kyle J. Gaulton et al.
NATURE GENETICS (2015)
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
Po-Ru Loh et al.
NATURE GENETICS (2015)
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Jian Yang et al.
NATURE GENETICS (2015)
An atlas of genetic correlations across human diseases and traits
Brendan Bulik-Sullivan et al.
NATURE GENETICS (2015)
Large-scale whole-genome sequencing of the Icelandic population
Daniel F. Gudbjartsson et al.
NATURE GENETICS (2015)
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Brendan K. Bulik-Sullivan et al.
NATURE GENETICS (2015)
Efficient Bayesian mixed-model analysis increases association power in large cohorts
Po-Ru Loh et al.
NATURE GENETICS (2015)
The genetics of diabetic complications
Emma Ahlqvist et al.
NATURE REVIEWS NEPHROLOGY (2015)
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
Melina Claussnitzer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Diagnostic utility of microarray testing in pregnancy loss
J. A. Rosenfeld et al.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2015)
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Adrian Cortes et al.
NATURE COMMUNICATIONS (2015)
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Jie Huang et al.
NATURE COMMUNICATIONS (2015)
Contribution of Large Region Joint Associations to Complex Traits Genetics
Guillaume Pare et al.
PLOS GENETICS (2015)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Thomas W. Winkler et al.
PLOS GENETICS (2015)
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
Cathie Sudlow et al.
PLOS MEDICINE (2015)
Second-generation PLINK: rising to the challenge of larger and richer datasets
Christopher C. Chang et al.
GIGASCIENCE (2015)
A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity
J. Philippe et al.
INTERNATIONAL JOURNAL OF OBESITY (2015)
Genetic Susceptibility Testing and Readiness to Control Weight: Results from a Randomized Controlled Trial
Susanne F. Meisel et al.
OBESITY (2015)
VEGAS2: Software for More Flexible Gene-Based Testing
Aniket Mishra et al.
TWIN RESEARCH AND HUMAN GENETICS (2015)
Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
Gina M. Peloso et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
KRLMM: an adaptive genotype calling method for common and low frequency variants
Ruijie Liu et al.
BMC BIOINFORMATICS (2014)
Using population isolates in genetic association studies
Konstantinos Hatzikotoulas et al.
BRIEFINGS IN FUNCTIONAL GENOMICS (2014)
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG Interferon-α-Based Regimens
A. J. Muir et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2014)
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update
L. B. Ramsey et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2014)
Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'
Patrick Deelen et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2014)
Genome-wide association tests of inversions with application to psoriasis
Jianzhong Ma et al.
HUMAN GENETICS (2014)
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
Amy L. Williams et al.
NATURE (2014)
An atlas of active enhancers across human cell types and tissues
Robin Andersson et al.
NATURE (2014)
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis et al.
NATURE (2014)
A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3
Aditya Murthy et al.
NATURE (2014)
Obesity-associated variants within FTO form long-range functional connections with IRX3
Scott Smemo et al.
NATURE (2014)
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Ida Moltke et al.
NATURE (2014)
Leveraging population admixture to characterize the heritability of complex traits
Noah Zaitlen et al.
NATURE GENETICS (2014)
Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer
Lars A. Forsberg et al.
NATURE GENETICS (2014)
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
Valgerdur Steinthorsdottir et al.
NATURE GENETICS (2014)
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Jason Flannick et al.
NATURE GENETICS (2014)
Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits
Paul L. Auer et al.
NATURE GENETICS (2014)
Quality control and conduct of genome-wide association meta-analyses
Thomas W. Winkler et al.
NATURE PROTOCOLS (2014)
Epistasis and quantitative traits: using model organisms to study gene-gene interactions
Trudy F. C. Mackay
NATURE REVIEWS GENETICS (2014)
Detecting epistasis in human complex traits
Wen-Hua Wei et al.
NATURE REVIEWS GENETICS (2014)
The contribution of genetic variants to disease depends on the ruler
John S. Witte et al.
NATURE REVIEWS GENETICS (2014)
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Giulio Genovese et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
Amit R. Majithia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
Maya Ghoussaini et al.
NATURE COMMUNICATIONS (2014)
Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations
Yun R. Li et al.
GENOME MEDICINE (2014)
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index
Clive J. Hoggart et al.
PLOS GENETICS (2014)
Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation
Taru Tukiainen et al.
PLOS GENETICS (2014)
Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers
Amy E. Taylor et al.
PLOS GENETICS (2014)
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake
Toshiko Tanaka et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2013)
Weight Loss after Gastric Bypass Is Associated with a Variant at 15q26.1
Ida J. Hatoum et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Fine Mapping and Identification of BMI Loci in African Americans
Jian Gong et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Beyond GWASs: Illuminating the Dark Road from Association to Function
Stacey L. Edwards et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Robust methods for population stratification in genome wide association studies
Li Liu et al.
BMC BIOINFORMATICS (2013)
Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study
Shona M. Kerr et al.
BMC MEDICAL GENETICS (2013)
Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
David Ellinghaus et al.
GASTROENTEROLOGY (2013)
Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease
C. J. Cardinale et al.
GENES AND IMMUNITY (2013)
Human Cardiovascular Disease IBC Chip-Wide Association with Weight Loss and Weight Regain in the Look AHEAD Trial
Jeanne M. McCaffery et al.
HUMAN HEREDITY (2013)
Challenges in reproducibility of genetic association studies: lessons learned from the obesity field
A. Li et al.
INTERNATIONAL JOURNAL OF OBESITY (2013)
Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications
Amelie Bonnefond et al.
NATURE GENETICS (2013)
iCOGS collection provides a collaborative model FOREWORD
Orli G. Bahcall
NATURE GENETICS (2013)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Sonja I. Berndt et al.
NATURE GENETICS (2013)
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity
Eleanor Wheeler et al.
NATURE GENETICS (2013)
The Genotype-Tissue Expression (GTEx) project
John Lonsdale et al.
NATURE GENETICS (2013)
Molecular genetic testing and the future of clinical genomics
Sara Huston Katsanis et al.
NATURE REVIEWS GENETICS (2013)
Bringing genome-wide association findings into clinical use
Teri A. Manolio
NATURE REVIEWS GENETICS (2013)
Contribution of Common PCSK1 Genetic Variants to Obesity in 8,359 Subjects from Multi-Ethnic American Population
Helene Choquet et al.
PLOS ONE (2013)
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
Megan L. Grove et al.
PLOS ONE (2013)
Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels
Gian Andri Thun et al.
PLOS GENETICS (2013)
Ubiquitous Polygenicity of Human Complex Traits: Genome-Wide Analysis of 49 Traits in Koreans
Jian Yang et al.
PLOS GENETICS (2013)
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
Melissa Beaudoin et al.
PLOS GENETICS (2013)
Inclusion of Gene-Gene and Gene-Environment Interactions Unlikely to Dramatically Improve Risk Prediction for Complex Diseases
Hugues Aschard et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
Five Years of GWAS Discovery
Peter M. Visscher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits
Samsiddhi Bhattacharjee et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
M3: an improved SNP calling algorithm for Illumina BeadArray data
Gengxin Li et al.
BIOINFORMATICS (2012)
optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants
T. S. Shah et al.
BIOINFORMATICS (2012)
zCall: a rare variant caller for array-based genotyping
Jacqueline I. Goldstein et al.
BIOINFORMATICS (2012)
Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity
John W. M. Creemers et al.
DIABETES (2012)
DNA microarray as a tool in establishing genetic relatedness-Current status and future prospects
Daniel Kling et al.
FORENSIC SCIENCE INTERNATIONAL-GENETICS (2012)
Fine-Scale Estimation of Location of Birth from Genome-Wide Single-Nucleotide Polymorphism Data
Clive J. Hoggart et al.
GENETICS (2012)
Annotation of functional variation in personal genomes using RegulomeDB
Alan P. Boyle et al.
GENOME RESEARCH (2012)
Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity
Julia S. El-Sayed Moustafa et al.
HUMAN MOLECULAR GENETICS (2012)
Human SH2B1 mutations are associated with maladaptive behaviors and obesity
Michael E. Doche et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
FTO genotype is associated with phenotypic variability of body mass index
Jian Yang et al.
NATURE (2012)
Reconstructing Native American population history
David Reich et al.
NATURE (2012)
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Atsuhiko Ichimura et al.
NATURE (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations
Yukinori Okada et al.
NATURE GENETICS (2012)
Meta-analysis identifies common variants associated with body mass index in east Asians
Wanqing Wen et al.
NATURE GENETICS (2012)
Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes
Amelie Bonnefond et al.
NATURE GENETICS (2012)
Detectable clonal mosaicism and its relationship to aging and cancer
Kevin B. Jacobs et al.
NATURE GENETICS (2012)
Detectable clonal mosaicism from birth to old age and its relationship to cancer
Cathy C. Laurie et al.
NATURE GENETICS (2012)
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
Jian Yang et al.
NATURE GENETICS (2012)
Mining electronic health records: towards better research applications and clinical care
Peter B. Jensen et al.
NATURE REVIEWS GENETICS (2012)
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
Lucas D. Ward et al.
NUCLEIC ACIDS RESEARCH (2012)
Psychological Responses to Genetic Testing for Weight Gain: A Vignette Study
Susanne F. Meisel et al.
OBESITY (2012)
The mystery of missing heritability: Genetic interactions create phantom heritability
Or Zuk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Chapter 11: Genome-Wide Association Studies
William S. Bush et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
Zari Dastani et al.
PLOS GENETICS (2012)
The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits
Benjamin F. Voight et al.
PLOS GENETICS (2012)
Genetics of Obesity: What have we Learned?
Helene Choquet et al.
CURRENT GENOMICS (2011)
A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes
G. Thanabalasingham et al.
DIABETOLOGIA (2011)
Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos
Nathan R. Treff et al.
FERTILITY AND STERILITY (2011)
Meta-Analysis of Gene-Environment Interaction: Joint Estimation of SNP and SNP x Environment Regression Coefficients
Alisa K. Manning et al.
GENETIC EPIDEMIOLOGY (2011)
A Fast Algorithm to Optimize SNP Prioritization for Gene-Gene and Gene-Environment Interactions
Wei Q. Deng et al.
GENETIC EPIDEMIOLOGY (2011)
Transethnic meta-analysis of genomewide association studies
Andrew P. Morris
GENETIC EPIDEMIOLOGY (2011)
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
Danielle M. Greenawalt et al.
GENOME RESEARCH (2011)
Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
Thomas J. Hoffmann et al.
GENOMICS (2011)
The answer is 17 years, what is the question: understanding time lags in translational research
Zoe Slote Morris et al.
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE (2011)
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
Patrick Brest et al.
NATURE GENETICS (2011)
A rare variant in MYH6 is associated with high risk of sick sinus syndrome
Hilma Holm et al.
NATURE GENETICS (2011)
Genotype and SNP calling from next-generation sequencing data
Rasmus Nielsen et al.
NATURE REVIEWS GENETICS (2011)
High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia
Dheeraj Malhotra et al.
NEURON (2011)
Genetic Polymorphisms in the Hypothalamic Pathway in Relation to Subsequent Weight Change - The DiOGenes Study
Huaidong Du et al.
PLOS ONE (2011)
Promise and pitfalls of the Immunochip
Adrian Cortes et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results
Naomi R. Wray et al.
PLOS BIOLOGY (2011)
Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals
Carl A. Anderson et al.
PLOS BIOLOGY (2011)
Interpretation of Association Signals and Identification of Causal Variants from Genome-wide Association Studies
Kai Wang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
A Versatile Gene-Based Test for Genome-wide Association Studies
Jimmy Z. Liu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
LocusZoom: regional visualization of genome-wide association scan results
Randall J. Pruim et al.
BIOINFORMATICS (2010)
METAL: fast and efficient meta-analysis of genomewide association scans
Cristen J. Willer et al.
BIOINFORMATICS (2010)
Successes of Genome-wide Association Studies
Robert J. Klein et al.
CELL (2010)
Strategies for Genetic Studies of Complex Diseases
Kai Wang et al.
CELL (2010)
Genetic Heterogeneity in Human Disease
Jon McClellan et al.
CELL (2010)
Assessment of High-Sensitivity C-Reactive Protein Levels as Diagnostic Discriminator of Maturity-Onset Diabetes of the Young Due to HNF1A Mutations
Katharine R. Owen et al.
DIABETES CARE (2010)
Maturity-onset diabetes of the young (MODY): how many cases are we missing?
B. M. Shields et al.
DIABETOLOGIA (2010)
A novel single-cell DNA fingerprinting method successfully distinguishes sibling human embryos
Nathan R. Treff et al.
FERTILITY AND STERILITY (2010)
Genome-Wide Meta-Analysis of Joint Tests for Genetic and Gene-Environment Interaction Effects
Hugues Aschard et al.
HUMAN HEREDITY (2010)
Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels
Qi Sun et al.
HUMAN MOLECULAR GENETICS (2010)
Large, rare chromosomal deletions associated with severe early-onset obesity
Elena G. Bochukova et al.
NATURE (2010)
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
R. G. Walters et al.
NATURE (2010)
Integrating common and rare genetic variation in diverse human populations
David M. Altshuler et al.
NATURE (2010)
Functional impact of global rare copy number variation in autism spectrum disorders
Dalila Pinto et al.
NATURE (2010)
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen et al.
NATURE (2010)
A map of human genome variation from population-scale sequencing
David Altshuler et al.
NATURE (2010)
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
Ju-Hyun Park et al.
NATURE GENETICS (2010)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes et al.
NATURE GENETICS (2010)
Common SNPs explain a large proportion of the heritability for human height
Jian Yang et al.
NATURE GENETICS (2010)
Overexpression of Fto leads to increased food intake and results in obesity
Chris Church et al.
NATURE GENETICS (2010)
cnvHap: an integrative population and haplotype-based multiplatform model of SNPs and CNVs
Lachlan J. M. Coin et al.
NATURE METHODS (2010)
Data quality control in genetic case-control association studies
Carl A. Anderson et al.
NATURE PROTOCOLS (2010)
Genome-wide association studies in diverse populations
Noah A. Rosenberg et al.
NATURE REVIEWS GENETICS (2010)
Genotype imputation for genome-wide association studies
Jonathan Marchini et al.
NATURE REVIEWS GENETICS (2010)
VIEWPOINT Missing heritability and strategies for finding the underlying causes of complex disease
Evan E. Eichler et al.
NATURE REVIEWS GENETICS (2010)
Genomewide Association Studies and Assessment of the Risk of Disease
Teri A. Manolio
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Linkage and Genome-wide Association Analysis of Obesity-related Phenotypes: Association of Weight With the MGAT1 Gene
Asa Johansson et al.
OBESITY (2010)
Biological Pathway-Based Genome-Wide Association Analysis Identified the Vasoactive Intestinal Peptide (VIP) Pathway Important for Obesity
Yong-Jun Liu et al.
OBESITY (2010)
Molecular Diagnosis of Neonatal Diabetes Mellitus Using Next-Generation Sequencing of the Whole Exome
Amelie Bonnefond et al.
PLOS ONE (2010)
Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor Gene Locus
Andre Scherag et al.
PLOS ONE (2010)
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration
Wei Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection
Sharon R. Grossman et al.
SCIENCE (2010)
The $1,000 genome, the $100,000 analysis?
Elaine R. Mardis
GENOME MEDICINE (2010)
Rare Variants Create Synthetic Genome-Wide Associations
Samuel P. Dickson et al.
PLOS BIOLOGY (2010)
A Genome-wide Association Study of Autism Reveals a Common Novel Risk Locus at 5p14.1
Deqiong Ma et al.
ANNALS OF HUMAN GENETICS (2009)
A Robust Genome-Wide Scan Statistic of the Wellcome Trust Case-Control Consortium
Jungnam Joo et al.
BIOMETRICS (2009)
Ten Putative Contributors to the Obesity Epidemic
Emily J. McAllister et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2009)
Haplotype-Based Analysis: A Summary of GAW16 Group 4 Analysis
Elizabeth Hauser et al.
GENETIC EPIDEMIOLOGY (2009)
Machine Learning in Genome-Wide Association Studies
Silke Szymczak et al.
GENETIC EPIDEMIOLOGY (2009)
Finding the missing heritability of complex diseases
Teri A. Manolio et al.
NATURE (2009)
Common genetic variants on 5p14.1 associate with autism spectrum disorders
Kai Wang et al.
NATURE (2009)
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
Dongliang Ge et al.
NATURE (2009)
Inactivation of the Fto gene protects from obesity
Julia Fischer et al.
NATURE (2009)
Reconstructing Indian population history
David Reich et al.
NATURE (2009)
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Cristen J. Willer et al.
NATURE GENETICS (2009)
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
David Meyre et al.
NATURE GENETICS (2009)
IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy
Vijayaprakash Suppiah et al.
NATURE GENETICS (2009)
Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C
Yasuhito Tanaka et al.
NATURE GENETICS (2009)
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
David-Alexandre Tregouet et al.
NATURE GENETICS (2009)
Human genetic variation and its contribution to complex traits
Kelly A. Frazer et al.
NATURE REVIEWS GENETICS (2009)
Bayesian statistical methods for genetic association studies
Matthew Stephens et al.
NATURE REVIEWS GENETICS (2009)
Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults
Marleen H. M. De Moor et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2009)
Genomewide Association Studies - Illuminating Biologic Pathways
Joel N. Hirschhorn
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Common Genetic Variation and Human Traits
David B. Goldstein
NEW ENGLAND JOURNAL OF MEDICINE (2009)
A Rare Variant in the Visfatin Gene (NAMPT/PBEF1) Is Associated With Protection From Obesity
Alexandra I. F. Blakemore et al.
OBESITY (2009)
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
Lucia A. Hindorff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
Sergey Nejentsev et al.
SCIENCE (2009)
Managing and Analyzing Next-Generation Sequence Data
Brent G. Richter et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size
Nicole Soranzo et al.
PLOS GENETICS (2009)
The Genome-wide Patterns of Variation Expose Significant Substructure in a Founder Population
Eveliina Jakkula et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1α are associated with C-reactive protein
Alexander P. Reiner et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Loci related to metabolic-syndrome pathways including LEPR, HNF1A, IL6R, and GCKR associate with plasma C-reactive protein:: The women's genome health study
Paul M. Ridker et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans
Anne-Kathrin Wermter et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Estimation of significance thresholds for genomewide association scans
Frank Dudbridge et al.
GENETIC EPIDEMIOLOGY (2008)
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
Itsik Pe'er et al.
GENETIC EPIDEMIOLOGY (2008)
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity
Yong-Jun Liu et al.
HUMAN MOLECULAR GENETICS (2008)
Genome-based prediction of common diseases: advances and prospects
A. Cecile J. W. Janssens et al.
HUMAN MOLECULAR GENETICS (2008)
The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals
N. Kurokawa et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors
Federico A. Monzon et al.
MODERN PATHOLOGY (2008)
Common nonsynonymous variants in PCSK1 confer risk of obesity
Michael Benzinou et al.
NATURE GENETICS (2008)
Genome-wide association analysis identifies 20 loci that influence adult height
Michael N. Weedon et al.
NATURE GENETICS (2008)
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Kazuki Yasuda et al.
NATURE GENETICS (2008)
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
Hiroyuki Unoki et al.
NATURE GENETICS (2008)
Many sequence variants affecting diversity of adult human height
Daniel F. Gudbjartsson et al.
NATURE GENETICS (2008)
Identification of ten loci associated with height highlights new biological pathways in human growth
Guillaume Lettre et al.
NATURE GENETICS (2008)
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs
Joshua M. Korn et al.
NATURE GENETICS (2008)
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
Mark I. McCarthy et al.
NATURE REVIEWS GENETICS (2008)
Heritability in the genomics era - concepts and misconceptions
Peter M. Visscher et al.
NATURE REVIEWS GENETICS (2008)
SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Discerning the ancestry of European Americans in genetic association studies
Alkes L. Price et al.
PLOS GENETICS (2008)
Genetic Mapping in Human Disease
David Altshuler et al.
SCIENCE (2008)
Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays
Nils Homer et al.
PLOS GENETICS (2008)
Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants
Anke Hinney et al.
PLOS ONE (2007)
Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma
Gudmar Thorleifsson et al.
SCIENCE (2007)
PLINK: A tool set for whole-genome association and population-based linkage analyses
Shaun Purcell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene
Fanny Stutzmann et al.
HUMAN MOLECULAR GENETICS (2007)
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases
A. Cecile J. W. Janssens et al.
GENETICS IN MEDICINE (2007)
A new multipoint method for genome-wide association studies by imputation of genotypes
Jonathan Marchini et al.
NATURE GENETICS (2007)
A multi-array multi-SNP genotyping algorithm for affymetrix SNP microarrays
Yuanyuan Xiao et al.
BIOINFORMATICS (2007)
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Paul R. Burton et al.
NATURE (2007)
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek et al.
NATURE (2007)
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
Jochen Hampe et al.
NATURE GENETICS (2007)
Why most published research findings are false
JPA Ioannidis
PLOS MEDICINE (2005)
Complement factor H polymorphism in age-related macular degeneration
RJ Klein et al.
SCIENCE (2005)
Complement factor H polymorphism and age-related macular degeneration
AO Edwards et al.
SCIENCE (2005)
Assessment and implications of linkage disequilibrium in genome-wide single-nucleotide polymorphism and microsatellite panels
EL Goode et al.
GENETIC EPIDEMIOLOGY (2005)
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
KE Lohmueller et al.
NATURE GENETICS (2003)
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
BG Challis et al.
HUMAN MOLECULAR GENETICS (2002)
Share Paper
