Journal
MOLECULES
Volume 24, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/molecules24071249
Keywords
trifluoromethylsulfides; trifluoromethylsulfoxides; oxidation; trifluoroperacetic acid; dihydrogen peroxide
Funding
- CNRS
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A simple and efficient protocol for the oxidation of trifluoromethyl, mono- and difluoromethyl sulfides to the corresponding sulfoxides without over-oxidation to sulfones, using TFPAA prepared in situ from trifluoroacetic acid and 15% H2O2 aqueous solution was developed. The methodology is suitable for a wide range of aromatic and aliphatic substrates in milligram and multigram scales.
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