4.5 Article

N-Chlorosuccinimide (NCS)-N,N-dimethylformamide (DMF), a reagent for the oxidation of benzylic alcohols to aldehydes and ketones

Journal

MOLECULAR DIVERSITY
Volume 24, Issue 2, Pages 437-442

Publisher

SPRINGER
DOI: 10.1007/s11030-019-09954-3

Keywords

N-Chlorosuccinimide (NCS); N,N-Dimethylformamide (DMF); Benzylic alcohol; Oxidation

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The oxidation of benzylic alcohol to corresponding aldehyde and ketone using N-chlorosuccinimide (NCS)-N,N-dimethylformamide (DMF) has been described. This method gives easy access to the corresponding carbonyl compounds under metal-free conditions, without the use of corrosive reagent at ambient temperature in good yield.

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