Related references
Note: Only part of the references are listed.Expanding the base editing scope in rice by using Cas9 variants
Kai Hua et al.
PLANT BIOTECHNOLOGY JOURNAL (2019)
Metabolic engineering of microorganisms for production of aromatic compounds
Damla Huccetogullari et al.
MICROBIAL CELL FACTORIES (2019)
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos
Erwei Zuo et al.
SCIENCE (2019)
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice
Shuai Jin et al.
SCIENCE (2019)
BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
Wen Jiang et al.
CELL RESEARCH (2018)
MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae
Yikang Zhou et al.
METABOLIC ENGINEERING (2018)
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
Seuk-Min Ryu et al.
NATURE BIOTECHNOLOGY (2018)
Base editing with a Cpf1-cytidine deaminase fusion
Xiaosa Li et al.
NATURE BIOTECHNOLOGY (2018)
Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER
Brandon G. Wong et al.
NATURE BIOTECHNOLOGY (2018)
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
Luke W. Koblan et al.
NATURE BIOTECHNOLOGY (2018)
Heterozygous diploid and interspecies SCRaMbLEing
Michael J. Shen et al.
NATURE COMMUNICATIONS (2018)
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
Lena Hochrein et al.
NATURE COMMUNICATIONS (2018)
Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
B. A. Blount et al.
NATURE COMMUNICATIONS (2018)
Precise control of SCRaMbLE in synthetic haploid and diploid yeast
Bin Jia et al.
NATURE COMMUNICATIONS (2018)
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES
Zhouqing Luo et al.
NATURE COMMUNICATIONS (2018)
Photosynthetic Production of Sunscreen Shinorine Using an Engineered Cyanobacterium
Guang Yang et al.
ACS SYNTHETIC BIOLOGY (2018)
Mutually Orthogonal DNA Replication Systems In Vivo
Garri A. Arzumanyan et al.
ACS SYNTHETIC BIOLOGY (2018)
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
Johnny H. Hu et al.
NATURE (2018)
CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window
Shakked O. Halperin et al.
NATURE (2018)
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion
Xiao Wang et al.
NATURE BIOTECHNOLOGY (2018)
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
Jason M. Gehrke et al.
NATURE BIOTECHNOLOGY (2018)
Engineered CRISPR-Cas9 nuclease with expanded targeting space
Hiroshi Nishimasu et al.
SCIENCE (2018)
Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants
Lei Yang et al.
PROTEIN & CELL (2018)
Scalable, Continuous Evolution of Genes at Mutation Rates above Genomic Error Thresholds
Arjun Ravikumar et al.
CELL (2018)
Developing a low-cost milliliter-scale chemostat array for precise control of cellular growth
David Skelding et al.
QUANTITATIVE BIOLOGY (2018)
Directed Evolution: Bringing New Chemistry to Life
Frances H. Arnold
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Engineering microbial cell factories for the production of plant natural products: from design principles to industrial-scale production
Xiaonan Liu et al.
MICROBIAL CELL FACTORIES (2017)
Genetically programmed chiral organoborane synthesis
S. B. Jennifer Kan et al.
NATURE (2017)
Programmable base editing of A.T to G.C in genomic DNA without DNA cleavage
Nicole M. Gaudelli et al.
NATURE (2017)
Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
Y. Bill Kim et al.
NATURE BIOTECHNOLOGY (2017)
Evolution of a split RNA polymerase as a versatile biosensor platform
Jinyue Pu et al.
NATURE CHEMICAL BIOLOGY (2017)
Continuous directed evolution of aminoacyl-tRNA synthetases
David Bryson et al.
NATURE CHEMICAL BIOLOGY (2017)
A multiplex culture system for the long-term growth of fission yeast cells
Celine Callens et al.
YEAST (2017)
Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
Holly A. Rees et al.
NATURE COMMUNICATIONS (2017)
Maltose Utilization as a Novel Selection Strategy for Continuous Evolution of Microbes with Enhanced Metabolite Production
Shu-De Liu et al.
ACS SYNTHETIC BIOLOGY (2017)
Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T: A base editors with higher efficiency and product purity
Alexis C. Komor et al.
SCIENCE ADVANCES (2017)
Engineering 'cell robots' for parallel and highly sensitive screening of biomolecules under in vivo conditions
Lifu Song et al.
SCIENTIFIC REPORTS (2017)
Design and evolution of enzymes for non-natural chemistry
Stephan C. Hammer et al.
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY (2017)
Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
Ahmed H. Badran et al.
NATURE (2016)
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Alexis C. Komor et al.
NATURE (2016)
Targeted AIDID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells
Yunqing Ma et al.
NATURE METHODS (2016)
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells
Gaelen T. Hess et al.
NATURE METHODS (2016)
Ultrahigh-throughput-directed enzyme evolution by absorbance-activated droplet sorting (AADS)
Fabrice Gielen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
Keiji Nishida et al.
SCIENCE (2016)
Directed evolution of cytochrome c for carbon-silicon bond formation: Bringing silicon to life
S. B. Jennifer Kan et al.
SCIENCE (2016)
In vivo continuous evolution of genes and pathways in yeast
Nathan Crook et al.
NATURE COMMUNICATIONS (2016)
antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters
Tilmann Weber et al.
NUCLEIC ACIDS RESEARCH (2015)
A Low Cost, Customizable Turbidostat for Use in Synthetic Circuit Characterization
Chris N. Takahashi et al.
ACS SYNTHETIC BIOLOGY (2015)
Recent advances in the evolutionary engineering of industrial biocatalysts
James D. Winkler et al.
GENOMICS (2014)
An orthogonal DNA replication system in yeast
Arjun Ravikumar et al.
NATURE CHEMICAL BIOLOGY (2014)
Metabolic evolution of two reducing equivalent-conserving pathways for high-yield succinate production in Escherichia coli
Xinna Zhu et al.
METABOLIC ENGINEERING (2014)
Improving carotenoids production in yeast via adaptive laboratory evolution
Luis H. Reyes et al.
METABOLIC ENGINEERING (2014)
Evolution-guided optimization of biosynthetic pathways
Srivatsan Raman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Genomically encoded analog memory with precise in vivo DNA writing in living cell populations
Fahim Farzadfard et al.
SCIENCE (2014)
Bacterial Growth and Adaptation in Microdroplet Chemostats
Slawomir Jakiela et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Genome replication engineering assisted continuous evolution (GREACE) to improve microbial tolerance for biofuels production
Guodong Luan et al.
BIOTECHNOLOGY FOR BIOFUELS (2013)
Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition
Erdal Toprak et al.
NATURE PROTOCOLS (2013)
Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM
Shawn P. Finney-Manchester et al.
NUCLEIC ACIDS RESEARCH (2013)
Availability of public goods shapes the evolution of competing metabolic strategies
Herwig Bachmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Long-Term Dynamics of Adaptation in Asexual Populations
Michael J. Wiser et al.
SCIENCE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Synthetic RNA devices to expedite the evolution of metabolite-producing microbes
Jina Yang et al.
NATURE COMMUNICATIONS (2013)
Electrode-free picoinjection of microfluidic drops
Brian O'Donovan et al.
LAB ON A CHIP (2012)
Genomic analysis of a key innovation in an experimental Escherichia coli population
Zachary D. Blount et al.
NATURE (2012)
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
Erdal Toprak et al.
NATURE GENETICS (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Optimizing non-natural protein function with directed evolution
Eric M. Brustad et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture
Kevin S. Lee et al.
LAB ON A CHIP (2011)
Millifluidic droplet analyser for microbiology
Larysa Baraban et al.
LAB ON A CHIP (2011)
A system for the continuous directed evolution of biomolecules
Kevin M. Esvelt et al.
NATURE (2011)
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design
Jessica S. Dymond et al.
NATURE (2011)
Laboratory evolution of glutathione biosynthesis reveals natural compensatory pathways
Karthik Veeravalli et al.
NATURE CHEMICAL BIOLOGY (2011)
Machine learning methods for metabolic pathway prediction
Joseph M. Dale et al.
BMC BIOINFORMATICS (2010)
Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli
Hani Goodarzi et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
High-throughput injection with microfluidics using picoinjectors
Adam R. Abate et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria
Emily P. Balskus et al.
SCIENCE (2010)
Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate
Kaemwich Jantama et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Re-engineering Escherichia coli for ethanol production
L. P. Yomano et al.
BIOTECHNOLOGY LETTERS (2008)
Decompressing emulsion droplets favors coalescence
Nicolas Bremond et al.
PHYSICAL REVIEW LETTERS (2008)
Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli
Zachary D. Blount et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Recombineering with tolC as a Selectable/Counter-selectable Marker: remodeling the rRNA Operons of Escherichia coli
Joseph A. DeVito
NUCLEIC ACIDS RESEARCH (2008)
Production of L-alanine by metabolically engineered Escherichia coli
Xueli Zhang et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)
Methylglyoxal bypass identified as source of chiral contamination in L(+) and D(-)-lactate fermentations by recombinant Escherichia coli
T. B. Grabar et al.
BIOTECHNOLOGY LETTERS (2006)
Fermentation of 12% (w/v) glucose to 1.2 M lactate by Escherichia coli strain SZ194 using mineral salts medium
S Zhou et al.
BIOTECHNOLOGY LETTERS (2006)
Directed evolution of enzymes and biosynthetic pathways
Tyler W. Johannes et al.
CURRENT OPINION IN MICROBIOLOGY (2006)
Fermentation of 10% (w/v) sugar to D(-)-lactate by engineered Escherichia coli B
S Zhou et al.
BIOTECHNOLOGY LETTERS (2005)
Six groups of the OXY β-lactamase evolved over millions of years in Klebsiella oxytoca
C Fevre et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat
FK Balagaddé et al.
SCIENCE (2005)
Geometrically mediated breakup of drops in microfluidic devices
DR Link et al.
PHYSICAL REVIEW LETTERS (2004)
Use of genome-scale microbial models for metabolic engineering
KR Patil et al.
CURRENT OPINION IN BIOTECHNOLOGY (2004)
Gene regulation by riboswitches
M Mandal et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Directed evolution of enzymes for product chemistry
F Valetti et al.
NATURAL PRODUCT REPORTS (2004)
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I
M Camps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
In vivo mutagenesis by Escherichia coli DNA polymerase I -: Ile709 in motif a functions in base selection
A Shinkai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Prokaryotic DNA polymerase I: Evolution, structure, and base flipping mechanism for nucleotide selection
PH Patel et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Dynamic pattern formation in a vesicle-generating microfluidic device
T Thorsen et al.
PHYSICAL REVIEW LETTERS (2001)
Efficient gene targeted random mutagenesis in genetically stable Escherichia coli strains
Celine Fabret et al.
NUCLEIC ACIDS RESEARCH (2000)
Share Paper
