Journal
MAYO CLINIC PROCEEDINGS
Volume 94, Issue 5, Pages 864-874Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mayocp.2018.09.025
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- Boston Scientific
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Oral anticoagulation is the dominant strategy for stroke prevention in patients with nonvalvular atrial fibrillation. However, lifelong oral anticoagulation is associated with major issues including inappropriate dosing, nonadherence, and adverse effects. Therefore, efforts have been made to develop site-specific therapy aimed to occlude the left atrial appendage, the anatomical site accountable for more than 90% of nonvalvular atrial fibrillation-related ischemic strokes. This review focuses on the growing literature to put into perspective the risk-balance ratio of left atrial appendage occlusion. (C) 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc.
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