Journal
LIPIDS IN HEALTH AND DISEASE
Volume 18, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s12944-019-1039-y
Keywords
Arachidonic acid; Dietary survey; Docosahexaenoic acid; Eicosapentaenoic acid; Long-chain polyunsaturated fatty acid
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Long-chain polyunsaturated fatty acids (LCPUFAs) have important roles in physiological homeostasis. Numerous studies have provided extensive information about the roles of n-3 LCPUFA, such as docosahexaenoic acid and eicosapentaenoic acid. Arachidonic acid (ARA) is one of the major n-6 LCPUFAs and its biological aspects have been well studied. However, nutritional information for ARA is limited, especially in adult humans. This review presents a framework of dietary ARA intake and the effects of ARA supplementation on LCPUFA metabolism in adult humans, and the nutritional significance of ARA and LCPUFA is discussed.
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