Related references
Note: Only part of the references are listed.Loss of cysteinyl-tRNA synthetase ( CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
M. Hayano et al.
CELL DEATH AND DIFFERENTIATION (2016)
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
Xiaofang Sun et al.
HEPATOLOGY (2016)
An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis
Wenli Guo et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2015)
An overview of molecular basis of iron metabolism regulation and the associated pathologies
Bruno Silva et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Hepcidin: regulation of the master iron regulator
Gautam Rishi et al.
BIOSCIENCE REPORTS (2015)
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells
David L. Schonberg et al.
CANCER CELL (2015)
The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells
Christophe Louandre et al.
CANCER LETTERS (2015)
Mechanism of the transferrin receptor 1 dysregulation in hepatocarcinogenesis
Iryna Kindrat et al.
CANCER RESEARCH (2015)
Hepcidin Regulation in Prostate and Its Disruption in Prostate Cancer
Lia Tesfay et al.
CANCER RESEARCH (2015)
Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses
Le Jiang et al.
CELL CYCLE (2015)
Disordered signaling governing ferroportin transcription favors breast cancer growth
Yue Chen et al.
CELLULAR SIGNALLING (2015)
Cancer cells with irons in the fire
Laura M. Bystrom et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
Mai Matsushita et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Glutaminolysis and Transferrin Regulate Ferroptosis
Minghui Gao et al.
MOLECULAR CELL (2015)
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang et al.
NATURE (2015)
HSPB1 as a novel regulator of ferroptotic cancer cell death
X. Sun et al.
ONCOGENE (2015)
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
Edna Ooko et al.
PHYTOMEDICINE (2015)
HDAC Inhibitors as Novel Anti-Cancer Therapeutics
Cristabelle Souza et al.
Recent Patents on Anti-Cancer Drug Discovery (2015)
Cellular and metabolic functions for autophagy in cancer cells
Candia M. Kenific et al.
TRENDS IN CELL BIOLOGY (2015)
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
Min-Young Kwon et al.
ONCOTARGET (2015)
Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin
Justin B. Goh et al.
SCIENTIFIC REPORTS (2015)
Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis
Joseph D. Mancias et al.
ELIFE (2015)
The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study
Antonio Maccio et al.
HAEMATOLOGICA (2015)
Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
Caiguo Zhang et al.
PROTEIN & CELL (2015)
Iron homeostasis in host defence and inflammation
Tomas Ganz et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Mechanistic and regulatory aspects of intestinal iron absorption
Sukru Gulec et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
Iron and Cancer Risk-A Systematic Review and Meta-analysis of the Epidemiological Evidence
Ana Fonseca-Nunes et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Disordered hepcidin-ferroportin signaling promotes breast cancer growth
Shuping Zhang et al.
CELLULAR SIGNALLING (2014)
Iron homeostasis and anemia markers in early breast cancer
Pierre-Jean Lamy et al.
CLINICA CHIMICA ACTA (2014)
Roles of the hepcidin-ferroportin axis and iron in cancer
Xian-Ning Wu et al.
EUROPEAN JOURNAL OF CANCER PREVENTION (2014)
Hepcidin and GDF15 in anemia of multiple myeloma
Shuchong Mei et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2014)
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
Rachid Skouta et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Anemia in diffuse large B-cell non-Hodgkin lymphoma: the role of interleukin-6, hepcidin and erythropoietin
Maria Chiara Tisi et al.
LEUKEMIA & LYMPHOMA (2014)
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Joseph D. Mancias et al.
NATURE (2014)
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
William E. Dowdle et al.
NATURE CELL BIOLOGY (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
The role of iron and reactive oxygen species in cell death
Scott J. Dixon et al.
NATURE CHEMICAL BIOLOGY (2014)
Synchronized renal tubular cell death involves ferroptosis
Andreas Linkermann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Scott J. Dixon et al.
ELIFE (2014)
The physiological functions of on regulatory proteins in iron homeostasis - an update
De-Liang Zhang et al.
FRONTIERS IN PHARMACOLOGY (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
Glutathione peroxidases
Regina Brigelius-Flohe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages
Ahmed A. Alkhateeb et al.
BREAST CANCER RESEARCH AND TREATMENT (2013)
Aminoferrocene-Based Prodrugs and Their Effects on Human Normal and Cancer Cells as Well as Bacterial Cells
Paul Marzenell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Alterations in expression profile of iron-related genes in colorectal cancer
Katarzyna Hamara et al.
MOLECULAR BIOLOGY REPORTS (2013)
Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin
Carolyn Sangokoya et al.
PLOS GENETICS (2013)
MicroRNA-210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes
Aijun Qiao et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
WNT signalling pathways as therapeutic targets in cancer
Jamie N. Anastas et al.
NATURE REVIEWS CANCER (2013)
Beyond TGFβ: roles of other TGFβ superfamily members in cancer
Lalage M. Wakefield et al.
NATURE REVIEWS CANCER (2013)
Iron and cancer: more ore to be mined
Suzy V. Torti et al.
NATURE REVIEWS CANCER (2013)
The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes
Weihong Hou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2012)
Hepcidin and iron homeostasis
Tomas Ganz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Mammalian iron metabolism and its control by iron regulatory proteins
Cole P. Anderson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Development of small-molecule probes that selectively kill cells induced to express mutant RAS
Michel Weiwer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Micromanaging Iron Homeostasis HYPOXIA-INDUCIBLE MICRO-RNA-210 SUPPRESSES IRON HOMEOSTASIS-RELATED PROTEINS
Yusuke Yoshioka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Aminoferrocene-Based Prodrugs Activated by Reactive Oxygen Species
Helen Hagen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Functions of DNA methylation: islands, start sites, gene bodies and beyond
Peter A. Jones
NATURE REVIEWS GENETICS (2012)
Hepcidin and Disorders of Iron Metabolism
Tomas Ganz et al.
ANNUAL REVIEW OF MEDICINE, VOL 62, 2011 (2011)
Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages
Nobuhiko Harada et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Regulation of cellular iron metabolism
Jian Wang et al.
BIOCHEMICAL JOURNAL (2011)
HEPCIDIN, ANAEMIA, AND PROSTATE CANCER
Toshihiko Tanno et al.
BJU INTERNATIONAL (2011)
Role of ferritin alterations in human breast cancer cells
Svitlana I. Shpyleva et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice
Matthew Taylor et al.
GASTROENTEROLOGY (2011)
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice
Mirco Castoldi et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
Alice T. Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Ferritin H induction by histone deacetylase inhibitors
Wei Wang et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen
Hany Onsy Habashy et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells
Immacolata Andolfo et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)
MicroRNA-196 Represses Bach1 Protein and Hepatitis C Virus Gene Expression in Human Hepatoma Cells Expressing Hepatitis C Viral Proteins
Weihong Hou et al.
HEPATOLOGY (2010)
miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period
Y. Liao et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
miR-214 Regulates Lactoferrin Expression and Pro-Apoptotic Function in Mammary Epithelial Cells
Yalin Liao et al.
JOURNAL OF NUTRITION (2010)
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
Frank Weinberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis
Zandra K. Pinnix et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Iron: An emerging factor in colorectal carcinogenesis
Anita C. G. Chua et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2010)
Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma
Takao Kamai et al.
BMC CANCER (2009)
Blinded by the Light: The Growing Complexity of p53
Karen H. Vousden et al.
CELL (2009)
MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2
Stephen Y. Chan et al.
CELL METABOLISM (2009)
miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation
Dale G. Schaar et al.
EXPERIMENTAL HEMATOLOGY (2009)
Ferritin Functions as a Proinflammatory Cytokine via Iron-Independent Protein Kinase C Zeta/Nuclear Factor KappaB-Regulated Signaling in Rat Hepatic Stellate Cells
Richard G. Ruddell et al.
HEPATOLOGY (2009)
An update on iron physiology
Manuel Munoz et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression
Constance Delaby et al.
BIOCHEMICAL JOURNAL (2008)
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
Wan Seok Yang et al.
CHEMISTRY & BIOLOGY (2008)
Increased hepcidin expression in colorectal carcinogenesis
Douglas G. Ward et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
A role for iron in Wnt signalling
M. J. Brookes et al.
ONCOGENE (2008)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
NATURE (2007)
The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer
Tracy R. Daniels et al.
CLINICAL IMMUNOLOGY (2006)
The transferrin receptor part II: Targeted delivery of therapeutic agents into cancer cells
Tracy R. Daniels et al.
CLINICAL IMMUNOLOGY (2006)
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis
KA O'Donnell et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
A role of SMAD4 in iron metabolism through the positive regulation of hepicidin expression
RH Wang et al.
CELL METABOLISM (2005)
Micrornas: Small RNAs with a big role in gene regulation
L He et al.
NATURE REVIEWS GENETICS (2004)
Signaling role of intracellular iron in NF-κB activation
SG Xiong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma et al.
CANCER CELL (2003)
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression
A Lymboussaki et al.
JOURNAL OF HEPATOLOGY (2003)
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
AT McKie et al.
MOLECULAR CELL (2000)