Journal
13TH OESO WORLD CONFERENCE: THE ESOPHAGIOME I
Volume 1380, Issue -, Pages 58-66Publisher
BLACKWELL SCIENCE PUBL
DOI: 10.1111/nyas.13151
Keywords
esophagus; pain; pharmacology
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Funding
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [P30DK048522] Funding Source: NIH RePORTER
- NIDDK NIH HHS [P30 DK048522] Funding Source: Medline
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Treatment of esophageal pain remains a major challenge for the clinician. Although many patients have heartburn and may respond to proton pump inhibitors, there in an unmet need for other treatment modalities in patients where there are no obvious pathological findings. Although analgesics are the mainstay in esophageal pain treatment, many patients are nonresponders to these drugs. The current concise review focuses on other systems affecting pain processing, where better understanding may serve as a framework for therapy. These are the parasympathetic nervous system, exercise, and personality profiles. Finally, treatment with analgesics for functional chest pain remains a challenge, and an overview of treatment with antidepressive drugs is provided.
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