Journal
JOURNAL OF SULFUR CHEMISTRY
Volume 40, Issue 5, Pages 469-478Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/17415993.2019.1602127
Keywords
Meldrum's acid; barbituric acid; acetylthiourea; arylglyoxal; 2-acetamido-4-arylthiazol-5-yl; one-pot three-component reaction
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An efficient method for the synthesis of 2-acetamido-4-arylthiazol-5-yl derivatives via a novel one-pot three-component reaction of arylglyoxals, 1,3-dicarbonyl compounds such as Meldrum's acid or barbituric acid, and acetylthiourea in ethanol is reported.
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