Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 11, Pages 6868-6878Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b00670
Keywords
-
Categories
Funding
- DST, India [EMR/2017/000319]
- DAE-BRNS [2018043702RP04978]
Ask authors/readers for more resources
A direct dehydrogenative cross-coupling of azoles [C(sp(2))-H] with dialkyl phosphites [P(O)-H] to access 2-phosphonated azoles using Cu(I)/Cu(II) as catalyst and K2S2O8/di-tert-butylperoxide as oxidant has been achieved. A remarkable advantage over reported procedures includes that oxazoles, imidazoles, benz(ox/othi/imid)azoles, and indole are found to react under optimized reaction conditions to provide corresponding adducts in high yields. The mechanistic insight of cross-coupling was obtained by deuterium kinetic isotope effect studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available