Novel aminothiazolyl-functionalized phosphonium ionic liquid as a scavenger for toxic metal ions from aqueous media; mining to useful antibiotic candidates

Heavy metal ions (HMIs) induce sever toxic and carcinogenic aspects through many mechanisms, which are not still understood. Therefore, the aim of this paper is to explorer new simple and efficient HMIs scavenger. In this endeavor, we have successfully fabricated a new aminothiazolyl-functionalized phosphonium ionic liquid (HATPS) for HMIs (Ag(I), Cu(II), Zn(II), Fe(III)) scavenging applications. Moreover, the scavenging outputs were examined as new antibiotic candidates. The new scavenger exhibited excellent scavenging efficiency (up to 96% in the case of Ag(I) for an initial Ag(I) ions concentration of 0.03 M and at 0.03 M of scavenger dose) and can be easily regenerated and reused. The preference of HATPS over polymer-based scavengers could be attributed to its simplicity, real-time monitoring and shorter reaction time. Furthermore, HATPS was used efficiently as a spectrophotometric probe for determination of Fe(III) in aqueous media with LOD for Fe(III) of 0.322 ppm. The antimicrobial survey revealed that the scavenging outputs exhibited a moderate to excellent broad-spectrum antibacterial efficacy with preferable potency against E. coli agents (MICE.coli = 25.5-128.0 mu g/mL) than against S.aureus (MICs.(aureus) = 32.5-250.0 mu g/mL) but lower activity as fungicides. On the basis of our findings, HATPS may offer a precious methodology for Fe(III) detection in the environmental and biological samples. (C) 2019 Elsevier B.V. All rights reserved.