Journal
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
Volume 42, Issue 9-10, Pages 238-248Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10826076.2019.1585615
Keywords
ADMET parameters; bioautography; lipophilicity; TLC in drug development
Funding
- Ministry of Education, Science and Technological Development of the Republic of Serbia [172008, 172017]
Ask authors/readers for more resources
Among widely used chromatographic methods modern thin-layer chromatography is not only the simplest to perform but is also considered as respectable analytical method in various phases of drug discovery and development processes such as monitoring of synthesis, identification of bioactive substances from various natural sources and their isolation and purification, determination of lipophilicity and other physico-chemical parameters, quantitative structure-activity relationship studies, bioautography, as well as qualitative and quantitative analysis of drugs and their metabolites. An overview of recently published papers dealing with application of thin-layer chromatography in medicinal chemistry is presented.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available