Related references
Note: Only part of the references are listed.Ovarian Cancer Cells Commonly Exhibit Defective STING Signaling Which Affects Sensitivity to Viral Oncolysis
Nina Mari Gual Pimenta de Queiroz et al.
MOLECULAR CANCER RESEARCH (2019)
Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy
Daniel Shae et al.
NATURE NANOTECHNOLOGY (2019)
Cancer immunoediting and resistance to T cell-based immunotherapy
Jake S. O'Donnell et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles
Shannon Grabosch et al.
ONCOGENE (2019)
Syntenin1/MDA-9 (SDCBP) induces immune evasion in triple-negative breast cancer by upregulating PD-L1
Jing Liu et al.
BREAST CANCER RESEARCH AND TREATMENT (2018)
Cytosolic DNA Sensing in Organismal Tumor Control
Claire Vanpouille-Box et al.
CANCER CELL (2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies
Frederick Arce Vargas et al.
CANCER CELL (2018)
Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine
Yee Sun Tan et al.
CLINICAL CANCER RESEARCH (2018)
Combination and inducible adjuvants targeting nucleic acid sensors
Burcu Temizoz et al.
CURRENT OPINION IN PHARMACOLOGY (2018)
Cancer immunotherapy beyond immune checkpoint inhibitors
Julian A. Marin-Acevedo et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Gut microbiome modulates efficacy of immune checkpoint inhibitors
Ming Yi et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Chimeric antigen receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward
Jian Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Next generation of immune checkpoint therapy in cancer: new developments and challenges
Julian A. Marin-Acevedo et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Lessons learned from the blockade of immune checkpoints in cancer immunotherapy
Xiaolei Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors
Erhao Zhang et al.
MOLECULAR CANCER (2018)
Advances on chimeric antigen receptor-modified T-cell therapy for oncotherapy
Yanyu Pang et al.
MOLECULAR CANCER (2018)
Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy
David R. Wilson et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)
Anti-CTLA-4 therapy requires an Fc domain for efficacy
Jessica R. Ingram et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer
Samuel Alvarez-Arguedas et al.
TRANSLATIONAL RESEARCH (2018)
Targeting the IDO1 pathway in cancer: from bench to bedside
Ming Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Abscopal effect of radiotherapy combined with immune checkpoint inhibitors
Yang Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors
Ming Yi et al.
MOLECULAR CANCER (2018)
Role of the cGAS-STING pathway in cancer development and oncotherapeutic approaches
Li Teng Khoo et al.
EMBO REPORTS (2018)
Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
Assaf Marcus et al.
IMMUNITY (2018)
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Haipeng Liu et al.
NATURE (2018)
Design of amidobenzimidazole STING receptor agonists with systemic activity
Joshi M. Ramanjulu et al.
NATURE (2018)
Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
Kelsey E. Sivick et al.
CELL REPORTS (2018)
The role of neoantigen in immune checkpoint blockade therapy
Ming Yi et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2018)
Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer
Heather L. Kinkead et al.
JCI INSIGHT (2018)
Antigen processing and immune regulation in the response to tumours
Emma Reeves et al.
IMMUNOLOGY (2017)
Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors
Tyrel T. Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes
Silvia Cerboni et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
New development in CAR-T cell therapy
Zhenguang Wang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Checkpoint inhibitors in hematological malignancies
Chi Young Ok et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Chimeric antigen receptor T cells: a novel therapy for solid tumors
Shengnan Yu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death
Bridget Larkin et al.
JOURNAL OF IMMUNOLOGY (2017)
Fate of micronuclei and micronucleated cells
Henning Hintzsche et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2017)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Shane M. Harding et al.
NATURE (2017)
A STING-activating nanovaccine for cancer immunotherapy
Min Luo et al.
NATURE NANOTECHNOLOGY (2017)
Evolutionary Origins of cGAS-STING Signaling
Shally R. Margolis et al.
TRENDS IN IMMUNOLOGY (2017)
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Angel Garcia-Diaz et al.
CELL REPORTS (2017)
Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity
Casey R. Ager et al.
CANCER IMMUNOLOGY RESEARCH (2017)
A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice
Jeremy B. Foote et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Manipulation of Innate and Adaptive Immunity through Cancer Vaccines
Elias J. Sayour et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2017)
Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
Irene Scarfo et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Development and clinical application of anti-HER2 monoclonal and bispecific antibodies for cancer treatment
Shengnan Yu et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2017)
Incorporation of functional elements enhances the antitumor capacity of CAR T cells
Le Qin et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2017)
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System
Stefano Santaguida et al.
DEVELOPMENTAL CELL (2017)
Blocking interferon γ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis
Marc Corbera-Bellalta et al.
ANNALS OF THE RHEUMATIC DISEASES (2016)
The anti-proliferative effects of type I IFN involve STAT6-mediated regulation of SP1 and BCL6
Yu-An Hsu et al.
CANCER LETTERS (2016)
Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis
Tianli Xia et al.
CANCER RESEARCH (2016)
Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells
Chih-Hang Anthony Tang et al.
CANCER RESEARCH (2016)
STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
Henrique Lemos et al.
CANCER RESEARCH (2016)
Oncolytic virus therapy: A new era of cancer treatment at dawn
Hiroshi Fukuhara et al.
CANCER SCIENCE (2016)
The cGAS-STING Defense Pathway and Its Counteraction by Viruses
Zhe Ma et al.
CELL HOST & MICROBE (2016)
The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
Samantha S. W. Ho et al.
IMMUNITY (2016)
Recognition of Endogenous Nucleic Acids by the Innate Immune System
Axel Roers et al.
IMMUNITY (2016)
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons
Elizabeth. C. Carroll et al.
IMMUNITY (2016)
The host STING pathway at the interface of cancer and immunity
Leticia Corrales et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
The microbiome and innate immunity
Christoph A. Thaiss et al.
NATURE (2016)
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing
Qi Chen et al.
NATURE IMMUNOLOGY (2016)
Activation of STING requires palmitoylation at the Golgi
Kojiro Mukai et al.
NATURE COMMUNICATIONS (2016)
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
Tianli Xia et al.
CELL REPORTS (2016)
Established T Cell-Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade
Ellen Moore et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Biomarkers for the Clinical Use of PD-1/PD-L1 Inhibitors in Non-Small-Cell Lung Cancer A Review
Adrian G. Sacher et al.
JAMA ONCOLOGY (2016)
STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice
Zili Wang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
New perspectives on type I IFNs in cancer
Thomas F. Gajewski et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2015)
Cancer immunotherapy: harnessing the immune system to battle cancer
Yiping Yang
JOURNAL OF CLINICAL INVESTIGATION (2015)
Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma
Takashi Nakamura et al.
JOURNAL OF CONTROLLED RELEASE (2015)
cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response to Francisella Infection
Kelly M. Storek et al.
JOURNAL OF IMMUNOLOGY (2015)
Chromothripsis from DNA damage in micronuclei
Cheng-Zhong Zhang et al.
NATURE (2015)
Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
Dongjun Peng et al.
NATURE (2015)
Diverse roles of STING-dependent signaling on the development of cancer
J. Ahn et al.
ONCOGENE (2015)
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
Siqi Liu et al.
SCIENCE (2015)
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
Juan Fu et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells
Yu J. Shen et al.
Cell Reports (2015)
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
Leticia Corrales et al.
CELL REPORTS (2015)
Immune Escape Mechanisms as a Guide for Cancer Immunotherapy
Gregory L. Beatty et al.
CLINICAL CANCER RESEARCH (2015)
STING: infection, inflammation and cancer
Glen N. Barber
NATURE REVIEWS IMMUNOLOGY (2015)
RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Adeline R. Lam et al.
CANCER RESEARCH (2014)
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Seng-Ryong Woo et al.
IMMUNITY (2014)
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Liufu Deng et al.
IMMUNITY (2014)
STING-Mediated DNA Sensing Promotes Antitumor and Autoimmune Responses to Dying Cells
Jared Klarquist et al.
JOURNAL OF IMMUNOLOGY (2014)
Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1
Takayuki Abe et al.
JOURNAL OF VIROLOGY (2014)
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
John W. Schoggins et al.
NATURE (2014)
Inflammation-driven carcinogenesis is mediated through STING
Jeonghyun Ahn et al.
NATURE COMMUNICATIONS (2014)
STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment
Takayuki Ohkuri et al.
CANCER IMMUNOLOGY RESEARCH (2014)
STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer
Dinesh Chandra et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Cyclic [G(2′,5′) pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
Pu Gao et al.
CELL (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
Joseph Conlon et al.
JOURNAL OF IMMUNOLOGY (2013)
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
Andrea Ablasser et al.
NATURE (2013)
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
Andrea Ablasser et al.
NATURE (2013)
STING and the innate immune response to nucleic acids in the cytosol
Dara L. Burdette et al.
NATURE IMMUNOLOGY (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
Daxing Gao et al.
SCIENCE (2013)
Type I interferon response and innate immune sensing of cancer
Mercedes B. Fuertes et al.
TRENDS IN IMMUNOLOGY (2013)
Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma
Evan J. Lipson et al.
CLINICAL CANCER RESEARCH (2011)
STING is a direct innate immune sensor of cyclic di-GMP
Dara L. Burdette et al.
NATURE (2011)
Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice
Abdullah S. Madhun et al.
VACCINE (2011)
Phase II Study on the Addition of ASA404 (Vadimezan; 5,6-Dimethylxanthenone-4-Acetic Acid) to Docetaxel in CRMPC
Roberto Pili et al.
CLINICAL CANCER RESEARCH (2010)
Viral apoptosis is induced by IRF-3-mediated activation of Bax
Saurabh Chattopadhyay et al.
EMBO JOURNAL (2010)
Adjuvants for cancer vaccines
Thomas W. Dubensky et al.
SEMINARS IN IMMUNOLOGY (2010)
Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800 mg/m2 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
Mark J. McKeage et al.
LUNG CANCER (2009)
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Hiroki Ishikawa et al.
NATURE (2009)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong et al.
IMMUNITY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma
AS Jassar et al.
CANCER RESEARCH (2005)
Expression of CCR-7, MIP-3β, and Th-1 chemokines in type IIFN-induced monocyte-derived dendritic cells:: importance for the rapid acquisition of potent migratory and functional activities
S Parlato et al.
BLOOD (2001)
Abnormal nuclear shape in solid tumors reflects mitotic instability
D Gisselsson et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Share Paper
