4.7 Review

The role of autophagy in maintaining intestinal mucosal barrier

Related references

Note: Only part of the references are listed.
Review Cell Biology

Curcumin: A naturally occurring autophagy modulator

Abolfazl Shakeri et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Editorial Material Cell Biology

Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine

Elizabeth Delorme-Axford et al.

AUTOPHAGY (2018)

Article Biochemistry & Molecular Biology

Deficiency of Atg6 impairs beneficial effect of metformin on intestinal stem cell aging in Drosophila

Hyun-Jin Na et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Cell Biology

The autophagic network and cancer

Marissa D. Rybstein et al.

NATURE CELL BIOLOGY (2018)

Review Microbiology

Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier

Eric C. Martens et al.

NATURE REVIEWS MICROBIOLOGY (2018)

Review Immunology

Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease

Shu-Ling Wang et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Multidisciplinary Sciences

Autophagy maintains stem cells and intestinal homeostasis in Drosophila

Peter Nagy et al.

SCIENTIFIC REPORTS (2018)

Review Biochemistry & Molecular Biology

The role of autophagy in colitis-associated colorectal cancer

Yuhui Wu et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2018)

Article Gastroenterology & Hepatology

Global patterns and trends in colorectal cancer incidence and mortality

Melina Arnold et al.

Article Biochemistry & Molecular Biology

Salmonella Co-opts Host Cell Chaperone-mediated Autophagy for Intracellular Growth

Vikash Singh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Gastroenterology & Hepatology

Inflammatory Bowel Disease Drugs: A Focus on Autophagy

Kirsty M. Hooper et al.

JOURNAL OF CROHNS & COLITIS (2017)

Article Cell Biology

New insights into autophagosome-lysosome fusion

Shuhei Nakamura et al.

JOURNAL OF CELL SCIENCE (2017)

Review Biochemistry & Molecular Biology

Autophagosome Maturation and Fusion

Fulvio Reggiori et al.

JOURNAL OF MOLECULAR BIOLOGY (2017)

Review Pharmacology & Pharmacy

Targeting Free Radicals in Oxidative Stress-Related Human Diseases

Patrik Poprac et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2017)

Review Biochemistry & Molecular Biology

New Insights into Vitamin D and Autophagy in Inflammatory Bowel Diseases

Hyun-Woo Suh et al.

CURRENT MEDICINAL CHEMISTRY (2017)

Review Oncology

Targeting autophagy in cancer

Jean M. Mulcahy Levy et al.

NATURE REVIEWS CANCER (2017)

Review Cell Biology

Fine-tuning autophagy: from transcriptional to posttranslational regulation

Joelle Botti-Millet et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)

Article Multidisciplinary Sciences

TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells

Eun A. Ra et al.

NATURE COMMUNICATIONS (2016)

Review Immunology

The Mucosal Immune System and Its Regulation by Autophagy

Agnieszka M. Kabat et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Medicine, Research & Experimental

Role of autophagy in the regulation of epithelial cell junctions

Prashant Nighot et al.

TISSUE BARRIERS (2016)

Review Biochemistry & Molecular Biology

Autophagy and oxidative stress in cardiovascular diseases

Yu Mei et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Article Cell Biology

Secretory autophagy

Marisa Ponpuak et al.

CURRENT OPINION IN CELL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide

J. L. Duan et al.

FREE RADICAL RESEARCH (2015)

Article Biochemistry & Molecular Biology

Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Prashant K. Nighot et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Editorial Material Cell Biology

WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome

Tassula Proikas-Cezanne et al.

JOURNAL OF CELL SCIENCE (2015)

Review Immunology

Autophagy and autophagy-related proteins in the immune system

Shusaku T. Shibutani et al.

NATURE IMMUNOLOGY (2015)

Article Oncology

Autophagy in colorectal cancer: An important switch from physiology to pathology

Florin Burada et al.

WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2015)

Review Biochemistry & Molecular Biology

Oxidative stress and autophagy: the clash between damage and metabolic needs

G. Filomeni et al.

CELL DEATH AND DIFFERENTIATION (2015)

Article Gastroenterology & Hepatology

Mo1778 Abnormal Activation of Crinophagy in Crohn's Disease Paneth Cells

Elodie Thachil et al.

GASTROENTEROLOGY (2015)

Review Cell Biology

Autophagy and human diseases

Peidu Jiang et al.

CELL RESEARCH (2014)

Article Cell & Tissue Engineering

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

Ciara Metcalfe et al.

CELL STEM CELL (2014)

Review Biochemistry & Molecular Biology

Getting ready for building: signaling and autophagosome biogenesis

Adi Abada et al.

EMBO REPORTS (2014)

Article Gastroenterology & Hepatology

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

Aleksandar D. Kostic et al.

GASTROENTEROLOGY (2014)

Article Surgery

A Novel Role of Autophagy in Intestinal Epithelial Stem Cell Proliferation and Renewal

S. Shaffiey et al.

JOURNAL OF SURGICAL RESEARCH (2014)

Article Multidisciplinary Sciences

A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3

Aditya Murthy et al.

NATURE (2014)

Article Multidisciplinary Sciences

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Kara G. Lassen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Gastroenterology & Hepatology

Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation

Bo Liu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)

Article Microbiology

Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria

Jamaal L. Benjamin et al.

CELL HOST & MICROBE (2013)

Article Oncology

Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

Muthu Selvakumaran et al.

CLINICAL CANCER RESEARCH (2013)

Article Biochemistry & Molecular Biology

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

Khushbu K. Patel et al.

EMBO JOURNAL (2013)

Article Multidisciplinary Sciences

Paneth cells as a site of origin for intestinal inflammation

Timon E. Adolph et al.

NATURE (2013)

Review Cell Biology

Emerging regulation and functions of autophagy

Patricia Boya et al.

NATURE CELL BIOLOGY (2013)

Letter Medicine, General & Internal

Autophagy in Human Health and Disease REPLY

Augustine M. K. Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Medicine, General & Internal

MECHANISMS OF DISEASE Autophagy in Human Health and Disease

Augustine M. K. Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Pathology

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

Lyndsay Murrow et al.

Annual Review of Pathology-Mechanisms of Disease (2012)

Article Cell Biology

Autophagy is active in normal colon mucosa

Jean-Francois Groulx et al.

AUTOPHAGY (2012)

Article Biochemistry & Molecular Biology

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

Hachung Chung et al.

Review Immunology

Common alleles that influence autophagy and the risk for inflammatory bowel disease

Agnes Gardet et al.

CURRENT OPINION IN IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers

Javier Munoz et al.

EMBO JOURNAL (2012)

Review Gastroenterology & Hepatology

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

Natalie A. Molodecky et al.

GASTROENTEROLOGY (2012)

Article Oncology

Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells

Hisanori Miki et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2012)

Article Multidisciplinary Sciences

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake

Oemer H. Yilmaz et al.

NATURE (2012)

Review Physiology

Tight, Junction Pore and Leak Pathways: A Dynamic Duo

Le Shen et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)

Review Cell Biology

The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease

Susanne Billmann-Born et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Antimicrobial peptides important in innate immunity

Andreas Cederlund et al.

FEBS JOURNAL (2011)

Article Gastroenterology & Hepatology

Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection

Netanya G. Sandler et al.

GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Crohn's disease: NOD2, autophagy and ER stress converge

Teresa Fritz et al.

Article Multidisciplinary Sciences

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato et al.

NATURE (2011)

Review Multidisciplinary Sciences

Autophagy in immunity and inflammation

Beth Levine et al.

NATURE (2011)

Review Microbiology

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

Charles L. Bevins et al.

NATURE REVIEWS MICROBIOLOGY (2011)

Article Multidisciplinary Sciences

Succession of microbial consortia in the developing infant gut microbiome

Jeremy E. Koenig et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Multidisciplinary Sciences

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

Douglas R. Green et al.

SCIENCE (2011)

Review Gastroenterology & Hepatology

ER stress and the unfolded protein response in intestinal inflammation

Michael A. McGuckin et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)

Article Gastroenterology & Hepatology

Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis

Andrew A. Maynard et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)

Article Biochemistry & Molecular Biology

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

Hilla Weidberg et al.

EMBO JOURNAL (2010)

Review Cell Biology

Eaten alive: a history of macroautophagy

Zhifen Yang et al.

NATURE CELL BIOLOGY (2010)

Article Genetics & Heredity

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

Dermot P. B. McGovern et al.

NATURE GENETICS (2010)

Article Medicine, General & Internal

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease.

Jean Frederic Colombel et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Gastroenterology & Hepatology

Intestinal epithelial cells in inflammatory bowel diseases

Giulia Roda et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2010)

Review Immunology

Immune adaptations that maintain homeostasis with the intestinal microbiota

Lora V. Hooper et al.

NATURE REVIEWS IMMUNOLOGY (2010)

Article Gastroenterology & Hepatology

Early but not late administration of glucagon-like peptide-2 following ileo-cecal resection augments putative intestinal stem cell expansion

Aaron P. Garrison et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)

Review Physiology

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

Laurens G. van der Flier et al.

ANNUAL REVIEW OF PHYSIOLOGY (2009)

Review Biochemistry & Molecular Biology

The paradox of autophagy and its implication in cancer etiology and therapy

Avital Eisenberg-Lerner et al.

APOPTOSIS (2009)

Review Biochemistry & Molecular Biology

Epithelial cell-cell junctions and plasma membrane domains

Ben N. G. Giepmans et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Article Biochemistry & Molecular Biology

Autophagy Suppresses Tumorigenesis through Elimination of p62

Robin Mathew et al.

Editorial Material Gastroenterology & Hepatology

Paneth Cell Development, Differentiation, and Function: New Molecular Cues

Thaddeus S. Stappenbeck

GASTROENTEROLOGY (2009)

Review Immunology

Immune Responses to the Microbiota at the Intestinal Mucosal Surface

Breck A. Duerkop et al.

IMMUNITY (2009)

Article Immunology

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Geethanjali Pickert et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Article Cell Biology

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Review Immunology

Intestinal mucosal barrier function in health and disease

Jerrold R. Turner

NATURE REVIEWS IMMUNOLOGY (2009)

Review Immunology

The gut microbiota shapes intestinal immune responses during health and disease

June L. Round et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Editorial Material Cell Biology

Autophagy Gives a Nod and a Wink to the Inflammasome and Paneth Cells in Crohn's Disease

Vojo Deretic et al.

DEVELOPMENTAL CELL (2008)

Review Biochemistry & Molecular Biology

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy

Jiefei Geng et al.

EMBO REPORTS (2008)

Article Neurosciences

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways

Yunxiang Zhu et al.

JOURNAL OF PHYSIOLOGY-LONDON (2008)

Article Multidisciplinary Sciences

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

Tatsuya Saitoh et al.

NATURE (2008)

Article Genetics & Heredity

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Jeffrey C. Barrett et al.

NATURE GENETICS (2008)

Article Multidisciplinary Sciences

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

Shipra Vaishnava et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Autophagy gene-dependent clearance of apoptotic cells during embryonic development

Xueping Qu et al.

Article Gastroenterology & Hepatology

Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment

Jessica A. Clark et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)

Article Gastroenterology & Hepatology

Muc2-deficient mice spontaneously develop colitis, indicating that Muc2 is critical for colonic protection

Maria Van der Sluis et al.

GASTROENTEROLOGY (2006)

Article Multidisciplinary Sciences

Metagenomic analysis of the human distal gut microbiome

Steven R. Gill et al.

SCIENCE (2006)

Review Cell Biology

Autophagy and cancer therapy

Yasuko Kondo et al.

AUTOPHAGY (2006)

Review Immunology

The role of enterocytes in the intestinal barrier function and antigen uptake

V Snoeck et al.

MICROBES AND INFECTION (2005)

Article Multidisciplinary Sciences

Wnt signalling in stem cells and cancer

T Reya et al.

NATURE (2005)

Article Multidisciplinary Sciences

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

KS Kobayashi et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

Autophagy defends cells against invading group a Streptococcus

I Nakagawa et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

The intestinal epithelial stem cell

E Marshman et al.

BIOESSAYS (2002)

Review Biochemistry & Molecular Biology

The multifaceted Paneth cell

EM Porter et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2002)

Article Oncology

Stem cells: the intestinal stem cell as a paradigm

SP Bach et al.

CARCINOGENESIS (2000)