Journal
JOURNAL OF CELL BIOLOGY
Volume 218, Issue 5, Pages 1429-1431Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201904069
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Funding
- Wellcome Trust/Department of Biotechnology India Alliance grant [IA/I/12/500523]
- Science and Engineering Research Board grant [EMR/2017/002273]
- Indian Institute of Science Education and Research Mohali
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Many different adaptor proteins activate the processivity of dynein-dynactin complexes and determine the specific cargo for retrograde transport by binding cargo receptors such as Rab GTP-binding (G) proteins. In this issue, Wang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806097) identify two GTPases that can function directly as dynein adaptors during endocytosis and are regulated by calcium.
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