4.6 Article

Covalent modification of Cys-239 in -tubulin by small molecules as a strategy to promote tubulin heterodimer degradation

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices

Geuncheol Gil et al.

ACS CHEMICAL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

Harinath Doodhi et al.

CURRENT BIOLOGY (2016)

Article Multidisciplinary Sciences

Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule

Jianhong Yang et al.

NATURE COMMUNICATIONS (2016)

Review Chemistry, Medicinal

Recent developments in tubulin polymerization inhibitors: An overview

Ramandeep Kaur et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Pharmacology & Pharmacy

Characterization of the Covalent Binding of N-Phenyl-N′-(2-chloroethyl)ureas to β-Tubulin: Importance of Glu198 in Microtubule Stability

Sebastien Fortin et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)

Article Chemistry, Medicinal

Drugs That Target Dynamic Microtubules: A New Molecular Perspective

Richard A. Stanton et al.

MEDICINAL RESEARCH REVIEWS (2011)

Review Biotechnology & Applied Microbiology

Microtubule-binding agents: a dynamic field of cancer therapeutics

Charles Dumontet et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Review Oncology

Microtubules and resistance to tubulin-binding agents

Maria Kavallaris

NATURE REVIEWS CANCER (2010)

Article Pharmacology & Pharmacy

The Epothilones: How Pharmacology Relates to Clinical Utility

Laura Boehnke Michaud

ANNALS OF PHARMACOTHERAPY (2009)

Article Biochemistry & Molecular Biology

The microtubule-targeting agent T0070907 induces proteasomal degradation of tubulin

Gianni Harris et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Article Biochemistry & Molecular Biology

Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes

Lixin Mi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Covalent binding to tubulin by isothiocyanates - A mechanism of cell growth arrest and apoptosis

Lixin Mi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin

Paola Bargagna-Mohan et al.

CHEMISTRY & BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Structural basis for an unexpected mode of SERM-mediated ER antagonism

YL Wu et al.

MOLECULAR CELL (2005)

Review Biochemistry & Molecular Biology

Microtubule-targeted anticancer agents and apoptosis

KN Bhalla

ONCOGENE (2003)

Review Biochemistry & Molecular Biology

Microtubules, microtubule-interfering agents and apoptosis

F Mollinedo et al.

APOPTOSIS (2003)