Use of IR Spectroscopy in Cancer Diagnosis. A Review

Results of studies of the use of FTIR spectroscopy in cancer diagnosis are reviewed. Materials studied include biological fluids, tissues, and model systems for studying experimental neoplasia. The methods for working with each system are described. A detailed description is given for the use of IR spectroscopy for cancer diagnosis and in the monitoring of cancer therapy for the evaluation of drug effectiveness and determination of the disease state. Statistical methods for processing the IR spectral data are presented. The main limitations to the use of IR spectroscopy for the diagnosis of oncological diseases and the potential for its introduction into clinical practice are described.