Journal
JAPANESE JOURNAL OF APPLIED PHYSICS
Volume 58, Issue -, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.7567/1347-4065/ab088a
Keywords
-
Categories
Funding
- JSPS KAKENHI [JP15H03768]
- JST-CREST [JPMJCR14F3]
- JST-A-STEP
- Casio Science Promotion Foundation
- Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) Project from TUT
Ask authors/readers for more resources
We aimed to establish an ion channel measurement system using a charge transfer type ion image sensor on which an artificial lipid bilayer membrane was formed. A supported lipid bilayer (SLB) was formed on the K+-sensitive membrane composed of polyvinyl chloride on the ion image sensor. Fluid SLB fully covered the sensor surface and consequently reduced the output potential of the ion sensor, keeping the Nernst response of the ion sensor. We measured the time course after changing K+ concentrations before and after the formation of a SLB. The temporal response of the output potential was decelerated after the SLB formation, because ion diffusion to the sensor surface was shielded by the SLB. We demonstrated the ion channel reconstruction and inhibitor addition using gramicidin and Ca2+. (c) 2019 The Japan Society of Applied Physics
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available