4.4 Review

Geographical structure of bat SARS-related coronaviruses

Journal

INFECTION GENETICS AND EVOLUTION
Volume 69, Issue -, Pages 224-229

Publisher

ELSEVIER
DOI: 10.1016/j.meegid.2019.02.001

Keywords

Bats; SARS; Geographical structure; Phylogeny; Host switch

Funding

  1. CAS Pioneer Hundred Talents Program
  2. WIV One-Three-Five Strategic Program [WIV-135-TP1]

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Bats are the natural reservoirs of severe acute respiratory syndrome coronavirus (SARS-CoV) which caused the outbreak of human SARS in 2002-2003. We introduce the genetic diversity of SARS-related coronaviruses (SARSr-CoVs) discovered in bats and provide insights on the bat origin of human SARS. We also analyze the viral geographical structure that may improve our understanding of the evolution of bat SARSr-CoVs.

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