Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2019, Issue 31-32, Pages 5424-5433Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201900526
Keywords
Flow chemistry; Heterocycles; Photochemistry; Pyocyanin; Natural products
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The synthesis of the naturally occurring toxin pyocyanin has been realized in a short 4 step sequence. The key photochemical reaction and isolation of the final product have been facilitated by the use of flow chemistry techniques and immobilised reagents. Using these procedures gram quantities of pyocyanin were easily prepared in high yield and purity.
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