Journal
ENVIRONMENTAL TOXICOLOGY
Volume 34, Issue 9, Pages 1043-1051Publisher
WILEY
DOI: 10.1002/tox.22775
Keywords
acetamiprid; Bombyx mori; midgut; growth and development
Categories
Funding
- Science & Technology support Program of Suzhou [SNG2017048]
- China Agriculture Research System [CARS-18-ZJ0106]
- Fund of SuZhou University of Science and Technology [XKZ2017001]
- Natural Science Fund for Colleges and Universities in Jiangsu Province [18KJB230004]
- Science & Technology support Program of Huzhou [2018GZ09]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
Ask authors/readers for more resources
Acetamiprid is widely used for agricultural pest control. However, it remains poorly understood whether the environmental residues of acetamiprid have the potential effects on economic insect. In this study, we evaluated the effects of acetamiprid on silkworm growth and development. The exposure to trace amounts of acetamiprid significantly decreased body weight, viability, and spinning ability. In addition, the activity of trypsin in the midgut was decreased after exposure. DGE and KEGG pathway enrichment analysis revealed that the significantly differentially expressed genes were mainly involved in nutrient metabolism, stress responses, and inflammation pathways. These results, in combination with hematoxylin-eosin staining and transmission electron microscopy, indicated that acetamiprid could cause oxidative damage to midgut, lead to inflammatory responses, and affect the activities of midgut digestive enzymes, thus resulting in abnormal growth and development. Our findings greatly contributed to the evaluation of the effects of acetamiprid residues on other nontarget beneficial insect.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available