Journal
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 172, Issue -, Pages 444-450Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2019.02.002
Keywords
Bisphenol analogues; Urine; Preschool-aged children; Nanjing suburb; Cumulative risk assessment
Categories
Funding
- National Natural Science Foundation of China [21876207, 21507165, 21507036, 41503115]
- Central Public-interest Scientific Research Institution Basal Research Fund [GYZX170303]
- scientific research fund of the Second Institute of Oceanography, SOA [JG1414]
- Double First-class University Project [CPU2018GY21, 24]
- China Postdoctoral Science Foundation [2018M640540]
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Due to the extensive use in consumer products, the bisphenols (BPs) pollution in the environments has aggravated and people are frequently exposed to BPs. In this research, four BPs, i.e., bisphenol A (BPA), bisphenol F (BPF), bisphenol S (BPS) and bisphenol AF (BPAF), were determined in urine samples collected from Gaochun District preschool-age children and the concentrations, distribution profiles, potential sources and cumulative risk assessment of the target compounds were studied. Total concentrations of 4 BPs ranged from 2 to 3113.1 ng/L, with the average concentration of 648.6 ng/L. BPA was the predominant congener (accounting for 94%), followed by BPS. Correlation analysis indicated a negative relationship between BPA and BPAF (R = -0.273, p < 0.05). The estimated daily intakes suggested that young females were more sensitive to BPs. Moreover, the cumulative risk for hazard quotient (HQ) of BPA has been evaluated and the results showed that no high risk had occurred. It provided basic information on the occurrence and human exposure to urinary BPs of preschool aged children from Gaochun District.
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